Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209734272> ?p ?o ?g. }
- W3209734272 endingPage "105253" @default.
- W3209734272 startingPage "105253" @default.
- W3209734272 abstract "To investigate the composition and function of ocular surface microbiome in healthy people from different altitudes.Thirty-two healthy people living in a high altitude region and 30 sex- and age-matched individuals living in a low altitude region were enrolled. Samples were collected from the lower conjunctival sac of one randomly chosen eye for each participant. 16S rRNA sequencing was conducted to study the bacterial community composition and predict gene function using PICRUSt software.Microbial diversity and richness was significantly decreased in samples from highlanders as calculated by Abundance-based Coverage Estimator (ACE) index, Chao1 index, and observed-species index (all p < 0.01). Principle coordinate analysis (PCoA) suggested significantly distinct clustering of the conjunctival sac bacterial communities between two groups (p = 0.03), especially the dominant genera. The relative abundances of Corynebacterium, Staphylococcus, and Anaerococcus were significantly enriched in highlanders, while those of Pseudomonas and Massilia were significantly decreased as compared with lowlanders (p < 0.01). In the functional annotation analysis, we found that 74 gene pathways, mainly in metabolism, differed in abundance. Pathways related to immune system diseases and infectious diseases were also enriched in highlanders.The composition and function of ocular surface microbiome in highlanders were distinct from those of lowlanders and our study may provide a reference catalog of the healthy conjunctival microbiome in highlanders." @default.
- W3209734272 created "2021-11-08" @default.
- W3209734272 creator A5015566428 @default.
- W3209734272 creator A5018350804 @default.
- W3209734272 creator A5024583859 @default.
- W3209734272 creator A5025167152 @default.
- W3209734272 creator A5044698860 @default.
- W3209734272 creator A5046044171 @default.
- W3209734272 creator A5051522793 @default.
- W3209734272 creator A5055306594 @default.
- W3209734272 creator A5057272677 @default.
- W3209734272 creator A5066102428 @default.
- W3209734272 creator A5085130854 @default.
- W3209734272 date "2021-12-01" @default.
- W3209734272 modified "2023-09-27" @default.
- W3209734272 title "Ocular microbial diversity, community structure, and function at high altitude" @default.
- W3209734272 cites W1972635216 @default.
- W3209734272 cites W1980143346 @default.
- W3209734272 cites W1981886354 @default.
- W3209734272 cites W1988821718 @default.
- W3209734272 cites W1989889539 @default.
- W3209734272 cites W1996690280 @default.
- W3209734272 cites W2003788503 @default.
- W3209734272 cites W2003895213 @default.
- W3209734272 cites W2017695421 @default.
- W3209734272 cites W2021079591 @default.
- W3209734272 cites W2073778161 @default.
- W3209734272 cites W2079643983 @default.
- W3209734272 cites W2080505182 @default.
- W3209734272 cites W2083618487 @default.
- W3209734272 cites W2095061901 @default.
- W3209734272 cites W2110300022 @default.
- W3209734272 cites W2131186249 @default.
- W3209734272 cites W2133856765 @default.
- W3209734272 cites W2143774628 @default.
- W3209734272 cites W2306621981 @default.
- W3209734272 cites W2316435817 @default.
- W3209734272 cites W2324897069 @default.
- W3209734272 cites W2338221131 @default.
- W3209734272 cites W2366175660 @default.
- W3209734272 cites W2529584280 @default.
- W3209734272 cites W2581864892 @default.
- W3209734272 cites W2590373630 @default.
- W3209734272 cites W2593928562 @default.
- W3209734272 cites W2737787547 @default.
- W3209734272 cites W2743596823 @default.
- W3209734272 cites W2750198255 @default.
- W3209734272 cites W2884639403 @default.
- W3209734272 cites W2909017506 @default.
- W3209734272 cites W2921565902 @default.
- W3209734272 cites W2921651523 @default.
- W3209734272 cites W2977822602 @default.
- W3209734272 cites W2988813668 @default.
- W3209734272 cites W2990782368 @default.
- W3209734272 cites W2992781282 @default.
- W3209734272 cites W3000940056 @default.
- W3209734272 cites W3005788008 @default.
- W3209734272 cites W3009017872 @default.
- W3209734272 cites W3042736690 @default.
- W3209734272 cites W3112239941 @default.
- W3209734272 doi "https://doi.org/10.1016/j.micpath.2021.105253" @default.
- W3209734272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34687837" @default.
- W3209734272 hasPublicationYear "2021" @default.
- W3209734272 type Work @default.
- W3209734272 sameAs 3209734272 @default.
- W3209734272 citedByCount "7" @default.
- W3209734272 countsByYear W32097342722022 @default.
- W3209734272 countsByYear W32097342722023 @default.
- W3209734272 crossrefType "journal-article" @default.
- W3209734272 hasAuthorship W3209734272A5015566428 @default.
- W3209734272 hasAuthorship W3209734272A5018350804 @default.
- W3209734272 hasAuthorship W3209734272A5024583859 @default.
- W3209734272 hasAuthorship W3209734272A5025167152 @default.
- W3209734272 hasAuthorship W3209734272A5044698860 @default.
- W3209734272 hasAuthorship W3209734272A5046044171 @default.
- W3209734272 hasAuthorship W3209734272A5051522793 @default.
- W3209734272 hasAuthorship W3209734272A5055306594 @default.
- W3209734272 hasAuthorship W3209734272A5057272677 @default.
- W3209734272 hasAuthorship W3209734272A5066102428 @default.
- W3209734272 hasAuthorship W3209734272A5085130854 @default.
- W3209734272 hasConcept C104317684 @default.
- W3209734272 hasConcept C122325731 @default.
- W3209734272 hasConcept C143121216 @default.
- W3209734272 hasConcept C15151743 @default.
- W3209734272 hasConcept C18903297 @default.
- W3209734272 hasConcept C23913935 @default.
- W3209734272 hasConcept C2524010 @default.
- W3209734272 hasConcept C30968088 @default.
- W3209734272 hasConcept C33923547 @default.
- W3209734272 hasConcept C42407357 @default.
- W3209734272 hasConcept C53565203 @default.
- W3209734272 hasConcept C54355233 @default.
- W3209734272 hasConcept C6350597 @default.
- W3209734272 hasConcept C77077793 @default.
- W3209734272 hasConcept C86803240 @default.
- W3209734272 hasConcept C90856448 @default.
- W3209734272 hasConceptScore W3209734272C104317684 @default.
- W3209734272 hasConceptScore W3209734272C122325731 @default.