FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209888963> ?p ?o ?g. }

• W3209888963 endingPage "2981" @default.
• W3209888963 startingPage "2973" @default.
• W3209888963 abstract "The most suitable method for predicting the glomerular filtration rate (GFR) in obesity is currently debated. Therefore, multiple GFR/creatinine clearance prediction methods were applied to (morbidly) obese and nonobese patients ranging from moderate renal impairment to glomerular hyperfiltration and their predictions were rated based on observed fosfomycin pharmacokinetics, as this model drug is exclusively eliminated via glomerular filtration.The GFR/creatinine clearance predictions via the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Modification of Diet in Renal Disease (MDRD; indexed and de-indexed by body surface area) and creatinine clearance via the Cockcroft-Gault formula (CLCRCG ) using different body size descriptors were compared to the fosfomycin clearance (CLFOF ) from 30 surgical patients (body mass index = 20.1-52.0 kg m-2 ), receiving 8000 mg as intravenous infusion.The concordance between CLFOF and creatinine clearance predictions was highest for CLCRCG employing either ideal body weight or adjusted body weight (if body mass >1.3 ideal body weight; CLCRCG_ABW-Schwartz , concordance-correlation coefficient [95% confidence interval] = 0.474 [0.156; 0.703], CCC) and GFR predictions via the de-indexed MDRD equation (concordance-correlation coefficient = 0.452 [0.137; 0.685]). The proportion of predicted GFR values within ±30% of the observed CLFOF (P30 = 72.3-76.7%) was only marginally lower than the reported P30 in the original CKD-EPI and MDRD publications (P30 = 84.1-90.0%).This analysis represents a successful proof-of-concept for evaluating GFR/creatinine clearance prediction methods: Across all body mass index classes CLCRCG_ABW-Schwartz or the de-indexed MDRD were most suitable for predicting creatinine clearance/GFR also in (morbidly) obese, CKD stage <3B individuals in therapeutic use. Their application is proposed in optimising doses for vital therapies in obese patients requiring monitoring of renal function (e.g. methotrexate dosing)." @default.
• W3209888963 created "2021-11-08" @default.
• W3209888963 creator A5007358380 @default.
• W3209888963 creator A5009945042 @default.
• W3209888963 creator A5031210648 @default.
• W3209888963 creator A5031983636 @default.
• W3209888963 creator A5055130996 @default.
• W3209888963 creator A5059755226 @default.
• W3209888963 creator A5067875437 @default.
• W3209888963 creator A5083247553 @default.
• W3209888963 creator A5089731984 @default.
• W3209888963 creator A5090466009 @default.
• W3209888963 date "2021-11-11" @default.
• W3209888963 modified "2023-09-27" @default.
• W3209888963 title "Evaluating prediction methods for glomerular filtration to optimise drug doses in obese and nonobese patients" @default.
• W3209888963 cites W1505595226 @default.
• W3209888963 cites W1550111394 @default.
• W3209888963 cites W1898569443 @default.
• W3209888963 cites W1965708830 @default.
• W3209888963 cites W1969640272 @default.
• W3209888963 cites W1977623079 @default.
• W3209888963 cites W1989525615 @default.
• W3209888963 cites W1991703638 @default.
• W3209888963 cites W1999402843 @default.
• W3209888963 cites W1999868780 @default.
• W3209888963 cites W2003056396 @default.
• W3209888963 cites W2004460025 @default.
• W3209888963 cites W2008770307 @default.
• W3209888963 cites W2020387733 @default.
• W3209888963 cites W2022379644 @default.
• W3209888963 cites W2030833828 @default.
• W3209888963 cites W2035138138 @default.
• W3209888963 cites W2036789134 @default.
• W3209888963 cites W2036846365 @default.
• W3209888963 cites W2059412778 @default.
• W3209888963 cites W2067387902 @default.
• W3209888963 cites W2070659825 @default.
• W3209888963 cites W2073742622 @default.
• W3209888963 cites W2084224378 @default.
• W3209888963 cites W2090746383 @default.
• W3209888963 cites W2093470872 @default.
• W3209888963 cites W2105225330 @default.
• W3209888963 cites W2107564745 @default.
• W3209888963 cites W2118625269 @default.
• W3209888963 cites W2131674147 @default.
• W3209888963 cites W2133750711 @default.
• W3209888963 cites W2142472196 @default.
• W3209888963 cites W2146841626 @default.
• W3209888963 cites W2148791322 @default.
• W3209888963 cites W2149199918 @default.
• W3209888963 cites W2153899710 @default.
• W3209888963 cites W2155080636 @default.
• W3209888963 cites W2155965977 @default.
• W3209888963 cites W22549871 @default.
• W3209888963 cites W2293035635 @default.
• W3209888963 cites W2313339984 @default.
• W3209888963 cites W2433440740 @default.
• W3209888963 cites W2725188872 @default.
• W3209888963 cites W2790726559 @default.
• W3209888963 cites W2893673243 @default.
• W3209888963 cites W2911413417 @default.
• W3209888963 cites W2944127871 @default.
• W3209888963 cites W2949083889 @default.
• W3209888963 cites W2956359130 @default.
• W3209888963 cites W2987819628 @default.
• W3209888963 cites W3127293440 @default.
• W3209888963 doi "https://doi.org/10.1111/bcp.15115" @default.
• W3209888963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34688225" @default.
• W3209888963 hasPublicationYear "2021" @default.
• W3209888963 type Work @default.
• W3209888963 sameAs 3209888963 @default.
• W3209888963 citedByCount "5" @default.
• W3209888963 countsByYear W32098889632022 @default.
• W3209888963 countsByYear W32098889632023 @default.
• W3209888963 crossrefType "journal-article" @default.
• W3209888963 hasAuthorship W3209888963A5007358380 @default.
• W3209888963 hasAuthorship W3209888963A5009945042 @default.
• W3209888963 hasAuthorship W3209888963A5031210648 @default.
• W3209888963 hasAuthorship W3209888963A5031983636 @default.
• W3209888963 hasAuthorship W3209888963A5055130996 @default.
• W3209888963 hasAuthorship W3209888963A5059755226 @default.
• W3209888963 hasAuthorship W3209888963A5067875437 @default.
• W3209888963 hasAuthorship W3209888963A5083247553 @default.
• W3209888963 hasAuthorship W3209888963A5089731984 @default.
• W3209888963 hasAuthorship W3209888963A5090466009 @default.
• W3209888963 hasBestOaLocation W32098889631 @default.
• W3209888963 hasConcept C105795698 @default.
• W3209888963 hasConcept C112705442 @default.
• W3209888963 hasConcept C126322002 @default.
• W3209888963 hasConcept C126894567 @default.
• W3209888963 hasConcept C134018914 @default.
• W3209888963 hasConcept C159641895 @default.
• W3209888963 hasConcept C160798450 @default.
• W3209888963 hasConcept C2777501473 @default.
• W3209888963 hasConcept C2778653478 @default.
• W3209888963 hasConcept C2780221984 @default.
• W3209888963 hasConcept C2780306776 @default.
• W3209888963 hasConcept C2781059462 @default.

• next