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• W3209911683 abstract "Significance For plants grown in a crowded environment, PHYTOCHROME INTERACTING FACTOR 7 (PIF7) plays a critical role by initiating a series of adaptive growth responses. Here, we demonstrate that, in addition to transcription activity and subcellular localization, the PIF7 protein level, which is stringently regulated, is also important for shade avoidance responses. We identified two ubiquitin-specific proteases, UBP12 and UBP13, which positively regulate rapid plant growth in response to shade light. These two ubiquitin proteases directly interact with PIF7 and protect the latter from destruction by 26S proteasomes. The dynamic changes of PIF7 abundance regulated by UBP12 and UBP13 provide insight into the roles of posttranslational modifications of PIF7 in integrating environmental changes with endogenous responses." @default.
• W3209911683 created "2021-11-08" @default.
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• W3209911683 date "2021-11-03" @default.
• W3209911683 modified "2023-10-12" @default.
• W3209911683 title "Ubiquitin-specific proteases UBP12 and UBP13 promote shade avoidance response by enhancing PIF7 stability" @default.
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• W3209911683 doi "https://doi.org/10.1073/pnas.2103633118" @default.
• W3209911683 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8609341" @default.
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