FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3209968163> ?p ?o ?g. }

• W3209968163 abstract "Objective: The genetic markers for the detection or treatment of cervical squamous cell carcinoma (CESC) are not yet complete. This study aimed to identify the role of MSMO1 (Alternative name: SC4MOL) in the occurrence and development of CESC. Methods: We evaluated the significance of MSMO1 expression in CESC by using analysis of a public dataset from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database. Oncomine and GEPIA2 were used to validate MSMO1 as an independent prognostic factor in CESC. Multiple tools were used to analyze the factors and functions associated with MSMO1, such as methylation, miRNA, and co-expressed genes. Furthermore, TIMER and TISIDB were used to study the relationship between MSMO1 expression and immunization in CESC. Results: MSMO1 was highly expressed in tumor specimens and could be used as an independent prognostic factor of CESC (p < 0.05). But Casiopeinas chemotherapeutics and p63 loss could reduce the expression of MSMO1. The level of methylation MSMO1 was significantly increased in tumor tissues but there was an insignificant effect on the prognosis. MSMO1 was also closely related to hsa-miR-23a-3p, hsa-miR-23b-3p, hsa-miR-130b-3p, and gene IDI1. Specifically, the expression level of MSMO1 had a significant negative correlation with the infiltration level of CD4+T cells, Macrophages, Neutrophils, and DCs in CESC. In addition, GSEA identified differential enrichment in systemic lupus erythematosus, vascular smooth muscle contraction, cytokine receptor interaction, focal adhesion, chemokine signaling pathway, and Leishmania infection pathway in KEGG. Conclusion: Our findings provide evidence of the implications of MSMO1 in tumors, suggesting that MSMO1 is a promising prognostic biomarker in CESC." @default.
• W3209968163 created "2021-11-08" @default.
• W3209968163 creator A5020380510 @default.
• W3209968163 creator A5030451110 @default.
• W3209968163 creator A5030591164 @default.
• W3209968163 creator A5030942972 @default.
• W3209968163 creator A5037328671 @default.
• W3209968163 creator A5064844857 @default.
• W3209968163 creator A5068274975 @default.
• W3209968163 creator A5086825261 @default.
• W3209968163 date "2021-10-25" @default.
• W3209968163 modified "2023-10-16" @default.
• W3209968163 title "The Clinical Significance and Immunization of MSMO1 in Cervical Squamous Cell Carcinoma Based on Bioinformatics Analysis" @default.
• W3209968163 cites W1506033400 @default.
• W3209968163 cites W2022063628 @default.
• W3209968163 cites W2026570544 @default.
• W3209968163 cites W2031431146 @default.
• W3209968163 cites W2037851943 @default.
• W3209968163 cites W2059073003 @default.
• W3209968163 cites W2081736014 @default.
• W3209968163 cites W2092566559 @default.
• W3209968163 cites W2101117089 @default.
• W3209968163 cites W2117977572 @default.
• W3209968163 cites W2141170380 @default.
• W3209968163 cites W2161053574 @default.
• W3209968163 cites W2588493576 @default.
• W3209968163 cites W2736730167 @default.
• W3209968163 cites W2755716296 @default.
• W3209968163 cites W2779695949 @default.
• W3209968163 cites W2900569176 @default.
• W3209968163 cites W2915433652 @default.
• W3209968163 cites W3028304854 @default.
• W3209968163 cites W3088047010 @default.
• W3209968163 doi "https://doi.org/10.3389/fgene.2021.705851" @default.
• W3209968163 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8573162" @default.
• W3209968163 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34759952" @default.
• W3209968163 hasPublicationYear "2021" @default.
• W3209968163 type Work @default.
• W3209968163 sameAs 3209968163 @default.
• W3209968163 citedByCount "4" @default.
• W3209968163 countsByYear W32099681632022 @default.
• W3209968163 countsByYear W32099681632023 @default.
• W3209968163 crossrefType "journal-article" @default.
• W3209968163 hasAuthorship W3209968163A5020380510 @default.
• W3209968163 hasAuthorship W3209968163A5030451110 @default.
• W3209968163 hasAuthorship W3209968163A5030591164 @default.
• W3209968163 hasAuthorship W3209968163A5030942972 @default.
• W3209968163 hasAuthorship W3209968163A5037328671 @default.
• W3209968163 hasAuthorship W3209968163A5064844857 @default.
• W3209968163 hasAuthorship W3209968163A5068274975 @default.
• W3209968163 hasAuthorship W3209968163A5086825261 @default.
• W3209968163 hasBestOaLocation W32099681631 @default.
• W3209968163 hasConcept C104317684 @default.
• W3209968163 hasConcept C121608353 @default.
• W3209968163 hasConcept C126322002 @default.
• W3209968163 hasConcept C13373296 @default.
• W3209968163 hasConcept C143998085 @default.
• W3209968163 hasConcept C145059251 @default.
• W3209968163 hasConcept C150194340 @default.
• W3209968163 hasConcept C152724338 @default.
• W3209968163 hasConcept C162317418 @default.
• W3209968163 hasConcept C203014093 @default.
• W3209968163 hasConcept C2776914184 @default.
• W3209968163 hasConcept C2778220009 @default.
• W3209968163 hasConcept C33288867 @default.
• W3209968163 hasConcept C502942594 @default.
• W3209968163 hasConcept C54355233 @default.
• W3209968163 hasConcept C60644358 @default.
• W3209968163 hasConcept C71924100 @default.
• W3209968163 hasConcept C86803240 @default.
• W3209968163 hasConceptScore W3209968163C104317684 @default.
• W3209968163 hasConceptScore W3209968163C121608353 @default.
• W3209968163 hasConceptScore W3209968163C126322002 @default.
• W3209968163 hasConceptScore W3209968163C13373296 @default.
• W3209968163 hasConceptScore W3209968163C143998085 @default.
• W3209968163 hasConceptScore W3209968163C145059251 @default.
• W3209968163 hasConceptScore W3209968163C150194340 @default.
• W3209968163 hasConceptScore W3209968163C152724338 @default.
• W3209968163 hasConceptScore W3209968163C162317418 @default.
• W3209968163 hasConceptScore W3209968163C203014093 @default.
• W3209968163 hasConceptScore W3209968163C2776914184 @default.
• W3209968163 hasConceptScore W3209968163C2778220009 @default.
• W3209968163 hasConceptScore W3209968163C33288867 @default.
• W3209968163 hasConceptScore W3209968163C502942594 @default.
• W3209968163 hasConceptScore W3209968163C54355233 @default.
• W3209968163 hasConceptScore W3209968163C60644358 @default.
• W3209968163 hasConceptScore W3209968163C71924100 @default.
• W3209968163 hasConceptScore W3209968163C86803240 @default.
• W3209968163 hasLocation W32099681631 @default.
• W3209968163 hasLocation W32099681632 @default.
• W3209968163 hasLocation W32099681633 @default.
• W3209968163 hasLocation W32099681634 @default.
• W3209968163 hasLocation W32099681635 @default.
• W3209968163 hasOpenAccess W3209968163 @default.
• W3209968163 hasPrimaryLocation W32099681631 @default.
• W3209968163 hasRelatedWork W1983904394 @default.
• W3209968163 hasRelatedWork W1988455047 @default.
• W3209968163 hasRelatedWork W2009966535 @default.
• W3209968163 hasRelatedWork W2026631764 @default.
• W3209968163 hasRelatedWork W2077423437 @default.

• next