FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210054414> ?p ?o ?g. }

• W3210054414 endingPage "S154" @default.
• W3210054414 startingPage "S153" @default.
• W3210054414 abstract "Age and medical co-morbidities are well-known risk factors for need for hospitalization in COVID-19. It is unclear whether, and which, baseline echocardiographic abnormalities may refine triage in the emergency department beyond clinical risk factors, and hence help identify patients at higher risk for need for hospitalization. We aimed to investigate echocardiographic variables associated with risk of hospitalization in COVID-19 patients. Electronic health records (EHR) were screened retrospectively to identify adults with a positive COVID-19 test throughout St. Luke’s University Health Network from March 1, 2020-October 31, 2020, and had a transthoracic echocardiogram (TTE) within 15-180 days prior. Baseline medical co-morbidities and echocardiographic variables were compared between patients stratified by hospitalization. Continuous variables were compared using Student’s t-test or Mann-Whitney U-test; categorical variables using the χ 2-test or Fisher’s Exact test. Univariate logistic regression was used to select significant predictors for multivariate analysis. Backward stepwise logistic regression was performed to identify predictors of need for hospitalization, a surrogate for mild versus moderate-severe disease. 193 patients met inclusion criteria (83 hospitalized). Mean TTE to COVID19 positivity time was 86±52 days. Hospitalized patients were older and more likely to suffer co-morbidities (Table 1). Age, medical co-morbidities and several echocardiographic variables predicted need for hospitalization. Multivariate analysis revealed age, coronary disease, COPD, and left atrial (LA) enlargement (≥4 cm) independently predicting hospitalization with excellent discrimination (AUC 0.809, figure 1). Estimates plots are depicted in Figure 2. We present, to our knowledge the first cohort indicating that LA enlargement, in a largely unselected population, is an independent marker of need for hospitalization (a surrogate for worse than mild disease) among COVID-19 patients, and could perhaps be considered in addition to clinical risk assessment in the ED, when available. Being “upstream” from the left ventricle (LV), LA enlargement is an indicator of sustained LV pressure and/or volume overload resulting from diverse etiologies, including hypertension, valvular heart disease, and ischemic heart disease. Hence, LA size has long been known to be an independent predictor of cardiovascular events, stroke, and all-cause mortality among patients with underlying cardiovascular disease as well as the general population. Importantly, LA diameter emerged as a more powerful predictor than LV hypertrophy of COVID-19 severity, as indicated by need for hospitalization.View Large Image Figure ViewerDownload Hi-res image Download (PPT)View Large Image Figure ViewerDownload Hi-res image Download (PPT)" @default.
• W3210054414 created "2021-11-08" @default.
• W3210054414 creator A5005083010 @default.
• W3210054414 creator A5007249025 @default.
• W3210054414 creator A5041659095 @default.
• W3210054414 creator A5043812167 @default.
• W3210054414 creator A5054894674 @default.
• W3210054414 creator A5071276861 @default.
• W3210054414 creator A5071685914 @default.
• W3210054414 creator A5068577270 @default.
• W3210054414 date "2021-10-01" @default.
• W3210054414 modified "2023-10-14" @default.
• W3210054414 title "382 Can Pre-Morbid Echocardiography, Beyond Clinical Risk Factors, Predict Need for Hospitalizing in COVID-19 Patients?" @default.
• W3210054414 doi "https://doi.org/10.1016/j.annemergmed.2021.09.397" @default.
• W3210054414 hasPublicationYear "2021" @default.
• W3210054414 type Work @default.
• W3210054414 sameAs 3210054414 @default.
• W3210054414 citedByCount "0" @default.
• W3210054414 crossrefType "journal-article" @default.
• W3210054414 hasAuthorship W3210054414A5005083010 @default.
• W3210054414 hasAuthorship W3210054414A5007249025 @default.
• W3210054414 hasAuthorship W3210054414A5041659095 @default.
• W3210054414 hasAuthorship W3210054414A5043812167 @default.
• W3210054414 hasAuthorship W3210054414A5054894674 @default.
• W3210054414 hasAuthorship W3210054414A5068577270 @default.
• W3210054414 hasAuthorship W3210054414A5071276861 @default.
• W3210054414 hasAuthorship W3210054414A5071685914 @default.
• W3210054414 hasBestOaLocation W32100544141 @default.
• W3210054414 hasConcept C116675565 @default.
• W3210054414 hasConcept C126322002 @default.
• W3210054414 hasConcept C159047783 @default.
• W3210054414 hasConcept C164705383 @default.
• W3210054414 hasConcept C177713679 @default.
• W3210054414 hasConcept C2779134260 @default.
• W3210054414 hasConcept C3006700255 @default.
• W3210054414 hasConcept C3007834351 @default.
• W3210054414 hasConcept C3008058167 @default.
• W3210054414 hasConcept C524204448 @default.
• W3210054414 hasConcept C71924100 @default.
• W3210054414 hasConceptScore W3210054414C116675565 @default.
• W3210054414 hasConceptScore W3210054414C126322002 @default.
• W3210054414 hasConceptScore W3210054414C159047783 @default.
• W3210054414 hasConceptScore W3210054414C164705383 @default.
• W3210054414 hasConceptScore W3210054414C177713679 @default.
• W3210054414 hasConceptScore W3210054414C2779134260 @default.
• W3210054414 hasConceptScore W3210054414C3006700255 @default.
• W3210054414 hasConceptScore W3210054414C3007834351 @default.
• W3210054414 hasConceptScore W3210054414C3008058167 @default.
• W3210054414 hasConceptScore W3210054414C524204448 @default.
• W3210054414 hasConceptScore W3210054414C71924100 @default.
• W3210054414 hasIssue "4" @default.
• W3210054414 hasLocation W32100544141 @default.
• W3210054414 hasLocation W32100544142 @default.
• W3210054414 hasLocation W32100544143 @default.
• W3210054414 hasOpenAccess W3210054414 @default.
• W3210054414 hasPrimaryLocation W32100544141 @default.
• W3210054414 hasRelatedWork W3009669391 @default.
• W3210054414 hasRelatedWork W3020699490 @default.
• W3210054414 hasRelatedWork W3036314732 @default.
• W3210054414 hasRelatedWork W3084498529 @default.
• W3210054414 hasRelatedWork W3176864053 @default.
• W3210054414 hasRelatedWork W3198183218 @default.
• W3210054414 hasRelatedWork W4205317059 @default.
• W3210054414 hasRelatedWork W4206669628 @default.
• W3210054414 hasRelatedWork W4292098121 @default.
• W3210054414 hasRelatedWork W4382894326 @default.
• W3210054414 hasVolume "78" @default.
• W3210054414 isParatext "false" @default.
• W3210054414 isRetracted "false" @default.
• W3210054414 magId "3210054414" @default.
• W3210054414 workType "article" @default.