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- W3210056426 abstract "Introduction: Incidentally detected gallbladder cancers (IGBC) in the UK form a miniscule proportion of the total number of cholecystectomies performed for benign gallbladder disease. However, the time, money and resources required to perform a histopathological evaluation of gall bladder specimens is considerable. The S- Gallop study examines if selective histological examination is feasible and if so aims to formulate a prospective protocol for the same. Methods: This is a retrospective multi-centre study involving 13 hospitals across South West England. Preliminary analyses of data from six of these centres has been done. All patients who underwent elective cholecystectomies for benign gallbladder disease in 10 years between January 2009 and December 2018 were included in the study. Their demographics, clinicopathological details and histological data were evaluated. Results: There were 23,165 cholecystectomies (16406 female; F:M=2.4:1) performed for ostensibly benign disease. Median age for cholecystectomy was 52.0 years. IGBC was discovered in only 67 cases. (27 female; F: M= 2:1). Median age for patients with incidental malignant histology was 77.5 years. All except 7 of these were adenocarcinomas. Conclusion: Analysis of the preliminary data of cholecystectomy for benign gallbladder disease points to demographic and clinicopathological differences between those with histologically proven benign disease and those proven to have a gallbladder malignancy.This data, if formulated into a protocol for selective histological examination, stands to save the National Health Service (NHS) in the UK upwards of 5 million pounds a year." @default.
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- W3210056426 date "2021-01-01" @default.
- W3210056426 modified "2023-10-14" @default.
- W3210056426 title "Tenability of selective histological examination of gallbladders following cholecystectomy operation: preliminary results of the S- GALLOP study" @default.
- W3210056426 doi "https://doi.org/10.1016/j.hpb.2021.08.239" @default.
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