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• W3210056831 endingPage "817" @default.
• W3210056831 startingPage "811" @default.
• W3210056831 abstract "Cyclic lipopeptides are substances with a high potential to act as antimicrobial agents. Jagaricin, produced by Janthinobacterium agaricidamnosum DSM 9628 and discovered in 2012, is a new member of this class with promising antifungal properties. However, further experiments to investigate future applications and/or conduct chemical derivatization to change properties and toxicity are impossible due to the limited access to jagaricin. Besides a high jagaricin concentration at the end of the fermentation process, a suitable downstream process is essential to generate appropriate amounts with the desired purity. In contrast to other amphiphilic molecules, jagaricin cannot be separated by foam fractionation since it is mainly attached to the surface of the microbial biomass. This technical report presents an overall process chain consisting of 11 individual steps to generate jagaricin in gram scale with a purity of over 95%." @default.
• W3210056831 created "2021-11-08" @default.
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• W3210056831 date "2021-10-27" @default.
• W3210056831 modified "2023-10-15" @default.
• W3210056831 title "Scalable downstream method for the cyclic lipopetide jagaricin" @default.
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• W3210056831 doi "https://doi.org/10.1002/elsc.202100079" @default.
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