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- W3210116712 abstract "Abstract Background Diffusion tensor imaging is a promising technique for determining the responsible lesion of cervical radiculopathy, but the selection and delineation of the region of interest (ROI) affects the results. To explore the impact of different ROI sketching methods on the repeatability and consistency of DTI measurement values in patients with cervical spondylotic radiculopathy (CSR). Methods This was a retrospective study that included CSR patients who underwent DTI imaging. The images were analyzed independently by two radiologists. Four delineation methods were used: free-hand method, maximum roundness, quadrilateral method, and multi-point averaging method. They re-examined the images 6 weeks later. To investigate the consistency between the two measurements and the reproducibility between two radiologists, the intra-class correlation coefficient (ICC) was used. Results A total of 42 CSR patients were enrolled in this study. The distribution of compressed nerve roots was five C4, eight C5, sixteen C6, eleven C7, and two C8. No difference was found among the four methods in fractional anisotropy (FA) or apparent diffusion coefficient (ADC), irrespective of radiologists. (all P>0.05). Similar results were observed between the first and second measurements (all P>0.05), but some significant differences were observed for radiologist 2 for the four-small rounds method (P=0.033). Between the two measurements and the two radiologists, the free-hand and single largest circle methods were the two methods with the highest ICC (all ICC >0.90). Conclusion For the delineation of DTI ROI in patients with CSR, the free-hand and single largest circle methods were the most consistent methods." @default.
- W3210116712 created "2021-11-08" @default.
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- W3210116712 date "2021-11-02" @default.
- W3210116712 modified "2023-10-16" @default.
- W3210116712 title "Comparison of Region-of-Interest Delineation Methods for Diffusion Tensor Imaging in Patients with Cervical Spondylotic Radiculopathy" @default.
- W3210116712 doi "https://doi.org/10.21203/rs.3.rs-1023507/v1" @default.
- W3210116712 hasPublicationYear "2021" @default.
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