FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210194640> ?p ?o ?g. }

• W3210194640 endingPage "108760" @default.
• W3210194640 startingPage "108760" @default.
• W3210194640 abstract "Neurotransmission at chemical synapses relies on the calcium-induced fusion of synaptic vesicles with the presynaptic membrane. The distance of the synaptic vesicle to the calcium channels determines the release probability and consequently the postsynaptic signal. Suitable models of the process need to capture both the mean and the variance observed in electrophysiological measurements of the postsynaptic current. In this work, we propose a method to directly compute the exact first- and second-order moments for signals generated by a linear reaction network under convolution with an impulse response function, rendering computationally expensive numerical simulations of the underlying stochastic counting process obsolete. We show that the autocorrelation of the process is central for the calculation of the filtered signal's second-order moments, and derive a system of PDEs for the cross-correlation functions (including the autocorrelations) of linear reaction networks with time-dependent rates. Finally, we employ our method to efficiently compare different spatial coarse graining approaches for a specific model of synaptic vesicle fusion. Beyond the application to neurotransmission processes, the developed theory can be applied to any linear reaction system that produces a filtered stochastic signal." @default.
• W3210194640 created "2021-11-08" @default.
• W3210194640 creator A5013730423 @default.
• W3210194640 creator A5019520155 @default.
• W3210194640 creator A5047265098 @default.
• W3210194640 creator A5057954330 @default.
• W3210194640 date "2022-01-01" @default.
• W3210194640 modified "2023-10-16" @default.
• W3210194640 title "Variance of filtered signals: Characterization for linear reaction networks and application to neurotransmission dynamics" @default.
• W3210194640 cites W1642251103 @default.
• W3210194640 cites W1964731537 @default.
• W3210194640 cites W1989721214 @default.
• W3210194640 cites W2021091726 @default.
• W3210194640 cites W2038556096 @default.
• W3210194640 cites W2040423213 @default.
• W3210194640 cites W2043098233 @default.
• W3210194640 cites W2058081413 @default.
• W3210194640 cites W2073391931 @default.
• W3210194640 cites W2082484689 @default.
• W3210194640 cites W2090662268 @default.
• W3210194640 cites W2099426010 @default.
• W3210194640 cites W2101310282 @default.
• W3210194640 cites W2118749647 @default.
• W3210194640 cites W2119179178 @default.
• W3210194640 cites W2123355036 @default.
• W3210194640 cites W2127535453 @default.
• W3210194640 cites W2128014106 @default.
• W3210194640 cites W2145654105 @default.
• W3210194640 cites W2151210215 @default.
• W3210194640 cites W2154100802 @default.
• W3210194640 cites W2563548139 @default.
• W3210194640 cites W2578173289 @default.
• W3210194640 cites W2771230123 @default.
• W3210194640 cites W2897284309 @default.
• W3210194640 cites W2901308272 @default.
• W3210194640 cites W2918514104 @default.
• W3210194640 cites W3007037284 @default.
• W3210194640 cites W3104744823 @default.
• W3210194640 cites W3106262409 @default.
• W3210194640 cites W3135825807 @default.
• W3210194640 doi "https://doi.org/10.1016/j.mbs.2021.108760" @default.
• W3210194640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34883103" @default.
• W3210194640 hasPublicationYear "2022" @default.
• W3210194640 type Work @default.
• W3210194640 sameAs 3210194640 @default.
• W3210194640 citedByCount "3" @default.
• W3210194640 countsByYear W32101946402023 @default.
• W3210194640 crossrefType "journal-article" @default.
• W3210194640 hasAuthorship W3210194640A5013730423 @default.
• W3210194640 hasAuthorship W3210194640A5019520155 @default.
• W3210194640 hasAuthorship W3210194640A5047265098 @default.
• W3210194640 hasAuthorship W3210194640A5057954330 @default.
• W3210194640 hasConcept C105795698 @default.
• W3210194640 hasConcept C106131492 @default.
• W3210194640 hasConcept C11413529 @default.
• W3210194640 hasConcept C121332964 @default.
• W3210194640 hasConcept C134306372 @default.
• W3210194640 hasConcept C139722471 @default.
• W3210194640 hasConcept C170493617 @default.
• W3210194640 hasConcept C185592680 @default.
• W3210194640 hasConcept C186060115 @default.
• W3210194640 hasConcept C197341189 @default.
• W3210194640 hasConcept C200170125 @default.
• W3210194640 hasConcept C31972630 @default.
• W3210194640 hasConcept C33923547 @default.
• W3210194640 hasConcept C41008148 @default.
• W3210194640 hasConcept C5297727 @default.
• W3210194640 hasConcept C55493867 @default.
• W3210194640 hasConcept C62520636 @default.
• W3210194640 hasConcept C70836080 @default.
• W3210194640 hasConcept C72279823 @default.
• W3210194640 hasConcept C86803240 @default.
• W3210194640 hasConceptScore W3210194640C105795698 @default.
• W3210194640 hasConceptScore W3210194640C106131492 @default.
• W3210194640 hasConceptScore W3210194640C11413529 @default.
• W3210194640 hasConceptScore W3210194640C121332964 @default.
• W3210194640 hasConceptScore W3210194640C134306372 @default.
• W3210194640 hasConceptScore W3210194640C139722471 @default.
• W3210194640 hasConceptScore W3210194640C170493617 @default.
• W3210194640 hasConceptScore W3210194640C185592680 @default.
• W3210194640 hasConceptScore W3210194640C186060115 @default.
• W3210194640 hasConceptScore W3210194640C197341189 @default.
• W3210194640 hasConceptScore W3210194640C200170125 @default.
• W3210194640 hasConceptScore W3210194640C31972630 @default.
• W3210194640 hasConceptScore W3210194640C33923547 @default.
• W3210194640 hasConceptScore W3210194640C41008148 @default.
• W3210194640 hasConceptScore W3210194640C5297727 @default.
• W3210194640 hasConceptScore W3210194640C55493867 @default.
• W3210194640 hasConceptScore W3210194640C62520636 @default.
• W3210194640 hasConceptScore W3210194640C70836080 @default.
• W3210194640 hasConceptScore W3210194640C72279823 @default.
• W3210194640 hasConceptScore W3210194640C86803240 @default.
• W3210194640 hasFunder F4320320879 @default.
• W3210194640 hasLocation W32101946401 @default.
• W3210194640 hasLocation W32101946402 @default.
• W3210194640 hasOpenAccess W3210194640 @default.
• W3210194640 hasPrimaryLocation W32101946401 @default.
• W3210194640 hasRelatedWork W1583330846 @default.

• next