Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210197474> ?p ?o ?g. }
- W3210197474 endingPage "1840" @default.
- W3210197474 startingPage "1840" @default.
- W3210197474 abstract "Bacterial infections constitute a threat to public health as antibiotics are becoming less effective due to the emergence of antimicrobial resistant strains and biofilm and persister formation. Antimicrobial peptides (AMPs) are considered excellent alternatives to antibiotics; however, they suffer from limitations related to their peptidic nature and possible toxicity. The present review critically evaluates the chemical characteristics and antibacterial effects of lipid and polymeric AMP delivery systems and coatings that offer the promise of enhancing the efficacy of AMPs, reducing their limitations and prolonging their half-life. Unfortunately, the antibacterial activities of these systems and coatings have mainly been evaluated in vitro against planktonic bacteria in less biologically relevant conditions, with only some studies focusing on the antibiofilm activities of the formulated AMPs and on the antibacterial effects in animal models. Further improvements of lipid and polymeric AMP delivery systems and coatings may involve the functionalization of these systems to better target the infections and an analysis of the antibacterial activities in biologically relevant environments. Based on the available data we proposed which polymeric AMP delivery system or coatings could be profitable for the treatment of the different hard-to-treat infections, such as bloodstream infections and catheter- or implant-related infections." @default.
- W3210197474 created "2021-11-08" @default.
- W3210197474 creator A5038766887 @default.
- W3210197474 creator A5039744686 @default.
- W3210197474 creator A5062066729 @default.
- W3210197474 creator A5089282036 @default.
- W3210197474 date "2021-11-02" @default.
- W3210197474 modified "2023-09-27" @default.
- W3210197474 title "Current Advances in Lipid and Polymeric Antimicrobial Peptide Delivery Systems and Coatings for the Prevention and Treatment of Bacterial Infections" @default.
- W3210197474 cites W1564553363 @default.
- W3210197474 cites W1842609426 @default.
- W3210197474 cites W195513463 @default.
- W3210197474 cites W1968265961 @default.
- W3210197474 cites W1968302138 @default.
- W3210197474 cites W1968418753 @default.
- W3210197474 cites W1975993453 @default.
- W3210197474 cites W1976610230 @default.
- W3210197474 cites W1979973356 @default.
- W3210197474 cites W1985429081 @default.
- W3210197474 cites W1989126381 @default.
- W3210197474 cites W1989309635 @default.
- W3210197474 cites W1991074335 @default.
- W3210197474 cites W1994147782 @default.
- W3210197474 cites W1998021083 @default.
- W3210197474 cites W1998624315 @default.
- W3210197474 cites W2003275588 @default.
- W3210197474 cites W2006512709 @default.
- W3210197474 cites W2007693496 @default.
- W3210197474 cites W2010312818 @default.
- W3210197474 cites W2013161496 @default.
- W3210197474 cites W2024342748 @default.
- W3210197474 cites W2024663449 @default.
- W3210197474 cites W2030574023 @default.
- W3210197474 cites W2033181557 @default.
- W3210197474 cites W2037797952 @default.
- W3210197474 cites W2039248354 @default.
- W3210197474 cites W2045359131 @default.
- W3210197474 cites W2045897279 @default.
- W3210197474 cites W2045927909 @default.
- W3210197474 cites W2047580124 @default.
- W3210197474 cites W2050877797 @default.
- W3210197474 cites W2052327379 @default.
- W3210197474 cites W2054602599 @default.
- W3210197474 cites W2054643418 @default.
- W3210197474 cites W2056205811 @default.
- W3210197474 cites W2058449852 @default.
- W3210197474 cites W2061831048 @default.
- W3210197474 cites W2063912388 @default.
- W3210197474 cites W2064659525 @default.
- W3210197474 cites W2067018811 @default.
- W3210197474 cites W2067412807 @default.
- W3210197474 cites W2070101741 @default.
- W3210197474 cites W2072515072 @default.
- W3210197474 cites W2074630757 @default.
- W3210197474 cites W2074906023 @default.
- W3210197474 cites W2076105958 @default.
- W3210197474 cites W2078683291 @default.
- W3210197474 cites W2079078103 @default.
- W3210197474 cites W2079685904 @default.
- W3210197474 cites W2079793032 @default.
- W3210197474 cites W2082811360 @default.
- W3210197474 cites W2084388967 @default.
- W3210197474 cites W2091233468 @default.
- W3210197474 cites W2092858957 @default.
- W3210197474 cites W2094847571 @default.
- W3210197474 cites W2095211254 @default.
- W3210197474 cites W2095279529 @default.
- W3210197474 cites W2095578934 @default.
- W3210197474 cites W2096669060 @default.
- W3210197474 cites W2097603366 @default.
- W3210197474 cites W2099356975 @default.
- W3210197474 cites W2102502090 @default.
- W3210197474 cites W2102857711 @default.
- W3210197474 cites W2103548070 @default.
- W3210197474 cites W2105489185 @default.
- W3210197474 cites W2113890306 @default.
- W3210197474 cites W2113983379 @default.
- W3210197474 cites W2115163071 @default.
- W3210197474 cites W2117770375 @default.
- W3210197474 cites W2125347207 @default.
- W3210197474 cites W2132295292 @default.
- W3210197474 cites W2134928186 @default.
- W3210197474 cites W2135367449 @default.
- W3210197474 cites W2138361094 @default.
- W3210197474 cites W2138749846 @default.
- W3210197474 cites W2139326763 @default.
- W3210197474 cites W2143619605 @default.
- W3210197474 cites W2144081123 @default.
- W3210197474 cites W2147116036 @default.
- W3210197474 cites W2150918607 @default.
- W3210197474 cites W2151402786 @default.
- W3210197474 cites W2153572893 @default.
- W3210197474 cites W2155482026 @default.
- W3210197474 cites W2155941624 @default.
- W3210197474 cites W2170686133 @default.
- W3210197474 cites W2187976253 @default.
- W3210197474 cites W2189865585 @default.
- W3210197474 cites W2190138846 @default.