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- W3210242722 abstract "目的 探究北京地区首诊于急诊科的急性心肌梗死(acute myocardial infarction,AMI)后并发急性心力衰竭(acute heart failure,AHF)患者5年生存状况以及预后相关影响因素.方法 将北京地区AHF注册登记研究中AMI后并发AHF的患者纳入研究,以5年全因死亡作为终点对患者进行随访,构建多因素Cox风险比例回归模型,探究影响AMI后并发AHF患者5年全因死亡的独立危险因素.结果 共计395例患者纳入研究,245例(62％)于5年随访期内死亡.入院时心率(HR=1.006,95％CI:1.001～1.011,P=0.022)、左心室前壁心肌梗死(HR=1.383,95％CI:1.058～1.806,P=0.017)、Killip心功能分级Ⅳ级(HR=1.836,95％CI:1.246～2.704,P=0.002)、并发心房颤动(HR=1.402,95％CI:1.010～1.945,P=0.043)、既往慢性肾脏病(HR=1.753,95％CI:1.235～2.488,P=0.002)、卒中或短暂性脑缺血发作病史(HR=1.272,95％CI:0.865～1.277,P=0.088)、脑钠肽/N-末端脑钠肽前体水平位于第三分位数(HR=1.597,95％CI:1.026～2.486,P=0.038)为5年全因死亡的独立危险因素;血清钠水平(HR=0.978,95％CI:0.956～1.001,P=0.064)、接受再灌注治疗(HR=0.558,95％CI:0.412～0.755,P<0.001)、随访期间坚持服用利尿剂(HR=0.626,95％CI:0.433～0.905,P=0.013)、β-受体阻滞剂(HR=0.455,95％CI:0.329～0.628,P<0.001)、抗血小板药物(HR=0.521,95％CI:0.381～0.714,P<0.001)以及他汀类药物(HR=0.650,95％CI:0.477～0.886,P=0.006)为独立保护性因素.结论 AMI后并发AHF患者接受再灌注治疗及其他指南推荐的药物治疗比例偏低,远期预后差,通过规范诊疗措施有希望改善患者的长期预后." @default.
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- W3210242722 date "2021-01-01" @default.
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- W3210242722 title "Risk factors and long-term outcome of patients presenting to emergency departments with acute heart failure after acute myocardial infarction" @default.
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