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• W3210256462 abstract "We demonstrate that ischemia-reperfusion injury occurs in all livers during NMP, though there are notable differences in gene expression between functional and nonfunctional livers. We further demonstrate that activation of the liver’s repair and homeostasis mechanisms through autophagy plays a vital role in the graft’s response to injury and may impact liver function. These findings indicate that liver autophagy might be a key therapeutic target for rehabilitating the function of severely injured or untransplantable livers." @default.
• W3210256462 created "2021-11-08" @default.
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• W3210256462 date "2022-01-01" @default.
• W3210256462 modified "2023-10-01" @default.
• W3210256462 title "Activation of autophagy during normothermic machine perfusion of discarded livers is associated with improved hepatocellular function" @default.
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• W3210256462 doi "https://doi.org/10.1152/ajpgi.00266.2021" @default.
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