Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210522267> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W3210522267 abstract "Abstract Background Hypertension is one of the major risk factors of cardiovascular events in patients with atrial fibrillation (AF). Low diastolic blood pressure (DBP) has been reported to be associated with the incidence of cardiovascular events, but current guidelines recommend an intensive blood pressure target of less than 130/80 mmHg for AF patients taking oral anticoagulants without mentioning the lower limits of DBP. Methods The Fushimi AF Registry is a community-based prospective survey of AF patients in a city of Japan. Follow-up data were available in 4,472 patients, and hypertensive patients who received prescription of any antihypertensive agents and whose systolic blood pressure was treated to less than 130 mmHg were available were examined (n=1,319). We divided the patients into four groups according to their DBP at baseline; G1 (DBP<60 mmHg, n=349), G2 (60≤DBP<70, n=434), G3 (70≤DBP<80, n=386) and G4 (80≤DBP, n=150), and compared the clinical background and outcomes among groups. Results The proportion of female was grater in G1 group, and the patients in G1 group were older. During the median follow-up of 2,458 days, in Kaplan-Meier analysis, the incidence rates of cardiovascular events (composite of cardiac death, ischemic stroke, systemic embolism, non-fatal myocardial infarction and heart failure hospitalization during follow up) were the highest in G1 group and the lowest in G3 group (G1: 7.2% per person-year vs. G2: 4.9% vs. G3: 2.2% vs. G4: 4.4%; p<0.01). Multivariate Cox proportional hazards regression analysis revealed that DBP was an independent determinant of cardiovascular events (G1 vs. G3; hazard ratio (HR): 1.96, 95% confidence intervals (CI): 1.39–2.76, G2 vs. G3; HR: 1.79, 95% CI: 1.28–2.50, G4 vs. G3; HR: 1.56, 95% CI: 0.99–2.45) (Figure 1). When we examined the association of DBP according to 10 mmHg increment, patients with excessively low DBP (<50 mmHg) had significantly higher incidence of cardiovascular events than patients with DBP of 70–79 mmHg (HR: 2.80, 95% CI: 1.81–4.33), and DBP exhibited J curve association with higher incidence of cardiovascular events (Figure 2). Conclusion In Japanese AF patients whose systolic blood pressure was treated to less than 130 mmHg, patients with excessively low DBP had significantly higher incidence of cardiovascular events, and DBP exhibited J curve association with higher incidence of cardiovascular events. FUNDunding Acknowledgement Type of funding sources: None." @default.
- W3210522267 created "2021-11-08" @default.
- W3210522267 creator A5002932814 @default.
- W3210522267 creator A5016164521 @default.
- W3210522267 creator A5022030714 @default.
- W3210522267 creator A5024550423 @default.
- W3210522267 creator A5032003867 @default.
- W3210522267 creator A5035471147 @default.
- W3210522267 creator A5043193338 @default.
- W3210522267 creator A5045471307 @default.
- W3210522267 creator A5052804510 @default.
- W3210522267 creator A5053158912 @default.
- W3210522267 creator A5067610161 @default.
- W3210522267 creator A5072002120 @default.
- W3210522267 creator A5074073864 @default.
- W3210522267 creator A5082103856 @default.
- W3210522267 creator A5083207179 @default.
- W3210522267 date "2021-10-01" @default.
- W3210522267 modified "2023-10-16" @default.
- W3210522267 title "The relationship between diastolic blood pressure and the risk of cardiovascular events in patients with atrial fibrillation whose systolic blood pressure was treated to less than 130 mmHg" @default.
- W3210522267 doi "https://doi.org/10.1093/eurheartj/ehab724.2387" @default.
- W3210522267 hasPublicationYear "2021" @default.
- W3210522267 type Work @default.
- W3210522267 sameAs 3210522267 @default.
- W3210522267 citedByCount "0" @default.
- W3210522267 crossrefType "journal-article" @default.
- W3210522267 hasAuthorship W3210522267A5002932814 @default.
- W3210522267 hasAuthorship W3210522267A5016164521 @default.
- W3210522267 hasAuthorship W3210522267A5022030714 @default.
- W3210522267 hasAuthorship W3210522267A5024550423 @default.
- W3210522267 hasAuthorship W3210522267A5032003867 @default.
- W3210522267 hasAuthorship W3210522267A5035471147 @default.
- W3210522267 hasAuthorship W3210522267A5043193338 @default.
- W3210522267 hasAuthorship W3210522267A5045471307 @default.
- W3210522267 hasAuthorship W3210522267A5052804510 @default.
- W3210522267 hasAuthorship W3210522267A5053158912 @default.
- W3210522267 hasAuthorship W3210522267A5067610161 @default.
- W3210522267 hasAuthorship W3210522267A5072002120 @default.
- W3210522267 hasAuthorship W3210522267A5074073864 @default.
- W3210522267 hasAuthorship W3210522267A5082103856 @default.
- W3210522267 hasAuthorship W3210522267A5083207179 @default.
- W3210522267 hasBestOaLocation W32105222671 @default.
- W3210522267 hasConcept C120665830 @default.
- W3210522267 hasConcept C121332964 @default.
- W3210522267 hasConcept C126322002 @default.
- W3210522267 hasConcept C127413603 @default.
- W3210522267 hasConcept C164705383 @default.
- W3210522267 hasConcept C2778198053 @default.
- W3210522267 hasConcept C2779161974 @default.
- W3210522267 hasConcept C2780645631 @default.
- W3210522267 hasConcept C500558357 @default.
- W3210522267 hasConcept C57900726 @default.
- W3210522267 hasConcept C61511704 @default.
- W3210522267 hasConcept C71924100 @default.
- W3210522267 hasConcept C78519656 @default.
- W3210522267 hasConcept C84393581 @default.
- W3210522267 hasConceptScore W3210522267C120665830 @default.
- W3210522267 hasConceptScore W3210522267C121332964 @default.
- W3210522267 hasConceptScore W3210522267C126322002 @default.
- W3210522267 hasConceptScore W3210522267C127413603 @default.
- W3210522267 hasConceptScore W3210522267C164705383 @default.
- W3210522267 hasConceptScore W3210522267C2778198053 @default.
- W3210522267 hasConceptScore W3210522267C2779161974 @default.
- W3210522267 hasConceptScore W3210522267C2780645631 @default.
- W3210522267 hasConceptScore W3210522267C500558357 @default.
- W3210522267 hasConceptScore W3210522267C57900726 @default.
- W3210522267 hasConceptScore W3210522267C61511704 @default.
- W3210522267 hasConceptScore W3210522267C71924100 @default.
- W3210522267 hasConceptScore W3210522267C78519656 @default.
- W3210522267 hasConceptScore W3210522267C84393581 @default.
- W3210522267 hasIssue "Supplement_1" @default.
- W3210522267 hasLocation W32105222671 @default.
- W3210522267 hasOpenAccess W3210522267 @default.
- W3210522267 hasPrimaryLocation W32105222671 @default.
- W3210522267 hasRelatedWork W2049397185 @default.
- W3210522267 hasRelatedWork W2067977631 @default.
- W3210522267 hasRelatedWork W2073453392 @default.
- W3210522267 hasRelatedWork W2125804349 @default.
- W3210522267 hasRelatedWork W2300086221 @default.
- W3210522267 hasRelatedWork W2348720246 @default.
- W3210522267 hasRelatedWork W2399063111 @default.
- W3210522267 hasRelatedWork W2789232128 @default.
- W3210522267 hasRelatedWork W2917172139 @default.
- W3210522267 hasRelatedWork W3029306217 @default.
- W3210522267 hasVolume "42" @default.
- W3210522267 isParatext "false" @default.
- W3210522267 isRetracted "false" @default.
- W3210522267 magId "3210522267" @default.
- W3210522267 workType "article" @default.