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• W3210603669 abstract "We determined the influence of gastro-oesophageal reflux disease (GERD) on quality of life (QOL) before and after functional-endoscopic-sinus-surgery (FESS) for chronic rhinosinusitis (CRS).Medically-recalcitrant CRS patients were recruited prior to FESS. GERD was diagnosed endoscopically. QOL was compared between patients with vs without GERD at baseline and one-year post-FESS.Of 187 CRS patients receiving FESS, 40 had GERD. Pre-operative QOL was significantly worse in CRS patients with vs without GERD. Pre-operative GERD health-related QOL (GERD-HRQL) and reflux symptom index (RSI) scores were both correlated with pre-operative SNOT-22 scores. Compared with non-GERD CRS patients, GERD patients demonstrated larger SNOT-22 improvements after FESS, such that post-operative SNOT-22 values were no longer significantly different between GERD and non-GERD groups. However, post-FESS, in patients with CRS without nasal polyps (unlike those with nasal polyps), the GERD (vs non-GERD) group suffered from greater sleep dysfunction and otologic/facial symptoms.Compared to CRS patients without GERD, those with GERD experienced poorer pre-operative QOL and greater QOL improvement after FESS.Associazione della malattia da reflusso gastroesofageo e la qualità di vita dei pazienti affetti da rinosinusite cronica.Abbiamo determinato l’impatto della malattia da reflusso gastroesofageo (GERD) sulla qualità della vita (QOL) prima e dopo chirurgia endoscopica funzionale nasosinusale (FESS) nel trattamento della rinosinusite cronica (CRS).I pazienti con CRS refrattari alle terapie mediche sono stati reclutati prima della FESS. La diagnosi di GERD è stata raggiunta endoscopicamente. La qualità della vita è stata confrontata tra pazienti con e senza GERD al basale e a un anno dopo la FESS.Dei 187 pazienti con CRS sottoposti a FESS, 40 erano affetti da GERD. La qualità della vita prima dell’intervento era significativamente peggiore nei pazienti affetti da CRS e con GERD rispetto a quelli senza GERD. I punteggi preoperatori della qualità della vita in relazione alla GERD (GERD-HRQL) e dell’indice dei sintomi da reflusso (RSI) sono stati correlati ciascuno con i punteggi SNOT-22 preoperatori. Rispetto ai pazienti con CRS senza GERD, i pazienti con GERD hanno dimostrato miglioramenti della SNOT-22 più significativi dopo trattamento FESS, i valori SNOT-22 postoperatori non erano più significativamente differenti tra i gruppi con GERD e senza GERD. Tuttavia, dopo la FESS, nei pazienti con CRS senza poliposi nasale (a differenza di quelli con poliposi nasale), il gruppo GERD (contro non-GERD) ha avuto una maggiore disfunzione del sonno e sintomi otologici/facciali.Rispetto ai pazienti con CRS senza GERD, quelli con GERD hanno beneficiato di un miglioramento della QOL maggiore dopo trattamento FESS." @default.
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• W3210603669 date "2021-10-01" @default.
• W3210603669 modified "2023-09-26" @default.
• W3210603669 title "Association of gastro-oesophageal reflux disease and quality of life in patients with chronic rhinosinusitis" @default.
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• W3210603669 doi "https://doi.org/10.14639/0392-100x-n1491" @default.
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