FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3210879314> ?p ?o ?g. }

• W3210879314 endingPage "1430" @default.
• W3210879314 startingPage "1420" @default.
• W3210879314 abstract "The continued increase in prevalence of methamphetamine use in the United States has resulted in a significant increase in the number of patients entering treatment for methamphetamine use. However, no robustly efficacious pharmacologic treatment for methamphetamine use or withdrawal has been identified to date after stopping methamphetamine use.Given the association between methamphetamine withdrawal and relapse during early treatment, this study tested a controlled d-amphetamine withdrawal paradigm among methamphetamine-using individuals.Treatment-seeking adults who used methamphetamine (N = 34; 47% female; 100% white) were enrolled in a 4-week, randomized, double-blind, placebo-controlled trial in a residential setting, in which all participants were maintained on d-amphetamine (30 mg BID) during week 1, then half were switched to placebo during weeks 2-3. All participants received placebo during week 4. Outcomes included vital signs, withdrawal, cravings for methamphetamine, mood, and cognition. Bivariate analyses tested treatment group differences on baseline demographic and outcome variables. Repeated measures models examined main and interaction effects of treatment over time.Participants were successfully randomized and safely stabilized on d-amphetamine. Craving for methamphetamine increased during weeks 2-3 in the placebo group relative to those on d-amphetamine. Interactions with age and heart rate were noted.To our knowledge, this is the first double-blind, placebo-controlled trial measuring pharmacologic effects of abruptly stopping controlled d-amphetamine administration in adults who use methamphetamine. Results support the potential of this withdrawal paradigm to further examine the efficacy of pharmacologic agents in ameliorating methamphetamine withdrawal symptoms." @default.
• W3210879314 created "2021-11-08" @default.
• W3210879314 creator A5028101780 @default.
• W3210879314 creator A5049508145 @default.
• W3210879314 creator A5054472146 @default.
• W3210879314 creator A5065177032 @default.
• W3210879314 creator A5070830846 @default.
• W3210879314 creator A5085436481 @default.
• W3210879314 date "2021-10-26" @default.
• W3210879314 modified "2023-10-16" @default.
• W3210879314 title "Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial" @default.
• W3210879314 cites W1639710292 @default.
• W3210879314 cites W1788132277 @default.
• W3210879314 cites W1879399529 @default.
• W3210879314 cites W1919196553 @default.
• W3210879314 cites W1969661654 @default.
• W3210879314 cites W1983201778 @default.
• W3210879314 cites W2003590685 @default.
• W3210879314 cites W2014166026 @default.
• W3210879314 cites W2020540700 @default.
• W3210879314 cites W2021375486 @default.
• W3210879314 cites W2021534324 @default.
• W3210879314 cites W2025984191 @default.
• W3210879314 cites W2040276248 @default.
• W3210879314 cites W2041505696 @default.
• W3210879314 cites W2052464626 @default.
• W3210879314 cites W2054713470 @default.
• W3210879314 cites W2062542275 @default.
• W3210879314 cites W2082962210 @default.
• W3210879314 cites W2114496529 @default.
• W3210879314 cites W2114613490 @default.
• W3210879314 cites W2117052590 @default.
• W3210879314 cites W2120912266 @default.
• W3210879314 cites W2134799962 @default.
• W3210879314 cites W2135222861 @default.
• W3210879314 cites W2136772960 @default.
• W3210879314 cites W2145470773 @default.
• W3210879314 cites W2158252144 @default.
• W3210879314 cites W2158265853 @default.
• W3210879314 cites W2160070901 @default.
• W3210879314 cites W2160512845 @default.
• W3210879314 cites W2941530449 @default.
• W3210879314 cites W3118735640 @default.
• W3210879314 cites W4247665917 @default.
• W3210879314 doi "https://doi.org/10.1177/02698811211050563" @default.
• W3210879314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34697965" @default.
• W3210879314 hasPublicationYear "2021" @default.
• W3210879314 type Work @default.
• W3210879314 sameAs 3210879314 @default.
• W3210879314 citedByCount "2" @default.
• W3210879314 countsByYear W32108793142022 @default.
• W3210879314 crossrefType "journal-article" @default.
• W3210879314 hasAuthorship W3210879314A5028101780 @default.
• W3210879314 hasAuthorship W3210879314A5049508145 @default.
• W3210879314 hasAuthorship W3210879314A5054472146 @default.
• W3210879314 hasAuthorship W3210879314A5065177032 @default.
• W3210879314 hasAuthorship W3210879314A5070830846 @default.
• W3210879314 hasAuthorship W3210879314A5085436481 @default.
• W3210879314 hasBestOaLocation W32108793142 @default.
• W3210879314 hasConcept C118552586 @default.
• W3210879314 hasConcept C126322002 @default.
• W3210879314 hasConcept C142724271 @default.
• W3210879314 hasConcept C15744967 @default.
• W3210879314 hasConcept C168563851 @default.
• W3210879314 hasConcept C204787440 @default.
• W3210879314 hasConcept C27081682 @default.
• W3210879314 hasConcept C2777193897 @default.
• W3210879314 hasConcept C2779541405 @default.
• W3210879314 hasConcept C2780376393 @default.
• W3210879314 hasConcept C2780733359 @default.
• W3210879314 hasConcept C42219234 @default.
• W3210879314 hasConcept C48856860 @default.
• W3210879314 hasConcept C513476851 @default.
• W3210879314 hasConcept C71924100 @default.
• W3210879314 hasConceptScore W3210879314C118552586 @default.
• W3210879314 hasConceptScore W3210879314C126322002 @default.
• W3210879314 hasConceptScore W3210879314C142724271 @default.
• W3210879314 hasConceptScore W3210879314C15744967 @default.
• W3210879314 hasConceptScore W3210879314C168563851 @default.
• W3210879314 hasConceptScore W3210879314C204787440 @default.
• W3210879314 hasConceptScore W3210879314C27081682 @default.
• W3210879314 hasConceptScore W3210879314C2777193897 @default.
• W3210879314 hasConceptScore W3210879314C2779541405 @default.
• W3210879314 hasConceptScore W3210879314C2780376393 @default.
• W3210879314 hasConceptScore W3210879314C2780733359 @default.
• W3210879314 hasConceptScore W3210879314C42219234 @default.
• W3210879314 hasConceptScore W3210879314C48856860 @default.
• W3210879314 hasConceptScore W3210879314C513476851 @default.
• W3210879314 hasConceptScore W3210879314C71924100 @default.
• W3210879314 hasFunder F4320337375 @default.
• W3210879314 hasIssue "11" @default.
• W3210879314 hasLocation W32108793141 @default.
• W3210879314 hasLocation W32108793142 @default.
• W3210879314 hasLocation W32108793143 @default.
• W3210879314 hasOpenAccess W3210879314 @default.
• W3210879314 hasPrimaryLocation W32108793141 @default.
• W3210879314 hasRelatedWork W1982340927 @default.
• W3210879314 hasRelatedWork W2002748398 @default.

• next