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- W3211051061 abstract "The development of high-throughput technology has provided a reliable technical guarantee for an increased amount of available data on biological networks. Network alignment is used to analyze these data to identify conserved functional network modules and understand evolutionary relationships across species. Thus, an efficient computational network aligner is needed for network alignment. In this paper, the classic bat algorithm is discretized and applied to the network alignment. The bat algorithm initializes the population randomly and then searches for the optimal solution iteratively. Based on the bat algorithm, the global pairwise alignment algorithm BatAlign is proposed. In BatAlign, the individual velocity and the position are represented by a discrete code. BatAlign uses a search algorithm based on objective function that uses the number of conserved edges as the objective function. The similarity between the networks is used to initialize the population. The experimental results showed that the algorithm was able to match proteins with high functional consistency and reach a relatively high topological quality." @default.
- W3211051061 created "2021-11-08" @default.
- W3211051061 creator A5001926598 @default.
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- W3211051061 date "2021-11-03" @default.
- W3211051061 modified "2023-09-27" @default.
- W3211051061 title "Pairwise Biological Network Alignment Based on Discrete Bat Algorithm" @default.
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- W3211051061 doi "https://doi.org/10.1155/2021/5548993" @default.
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- W3211051061 hasPublicationYear "2021" @default.
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