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• W3211148132 abstract "Background: Hyperlipidemia is a condition where there is an increase or decrease in the lipid fraction in the blood due to a metabolic disorder of the lipid itself. The lipid fraction that experienced abnormalities was usually an increase in total cholesterol, triglycerides, LDL cholesterol and a decrease in HDL cholesterol (Perkeni, 2015). Anthocyanin compounds are one of the flavonoid compounds that have the potential as an alternative therapy for dyslipidemia. The leaves of red chicken (Amaranthus tricolor L.) contain anthocyanin compounds that can be used as an alternative therapy for hyperlipidemia.Objective: To determine the effect of red spinach leaf extract (Amaranthus tricolor L.) on LDL and HDL blood of white wistar rats induced by a high-fat diet.Methodology: Methods Reviewing articles according to the issue to be studied. It was carried out according to the PICOST analysis, namely population, intervention, comparison, output, study and times from 583 selected journals and 5 journals. Results: Literature from 5 journals contained 5 journals discussing red spinach leaf extract (Amaranthus tricolor L.) (100%), 5 journals discussing high-fat diets (100%), 4 journals discussing blood LDL (80%) and 3 journals. discussed blood HDL (60%). Conclusion: The administration of red spinach leaf extract (Amaranthus tricolor L.) affected the blood LDL of rats at a dose of 200 mg/kg BW to 800 mg/kg BW and HDL rat blood at a dose of 200 mg/kg BW to 400 mg/kg BW . ABSTRAK Latar Belakang : Hiperlipidemia adalah keadaan dimana terjadinya peningkatan ataupun penurunan fraksi lipid dalam darah karena adanya suatu kelainan metabolisme dari lipid itu sendiri. Fraksi lipid yang mengalami kelainan biasanya adalah kenaikan kadar kolesterol total, trigliserida Keywords: High Fat Diet, LDL, HDL, Red Spinach Leaf Extract , kolesterol LDL dan penurunan dari kolesterol HDL (Perkeni, 2015). Senyawa antosianin merupakan salah satu senyawa flavonoid yang dapat berpotensi sebagai terapi alternatif untuk dislipidemia. Pada daun ayam merah (Amaranthus tricolor L.) terdapat senyawaantosianin yang dapat digunakan sebagai terapi alternative hiperlipidemia.Tujuan : Mengetahui pengaruh pemberian ekstrak daun bayam merah (Amaranthus tricolor L.) terhadap LDL dan HDL darah tikus putih wistar yang diinduksi diet tinggi lemak.Metodologi : Melakukan telaah artikel sesuai dengan issue yang akan diteliti. Dilakukan sesuai dengan analisis PICOST yaitu population, intervention, comparation, output, studi dan times dari 583 jurnal terpilih 5 jurnal.Hasil : Literature dari 5 jurnal terdapat 5 jurnal yang membahas tentang ekstrak daun bayam merah (Amaranthus tricolor L.) (100%), 5 jurnal membahas diet tinggi lemak (100%), 4 jurnal membahas LDL darah (80%) dan 3 jurnal membahas HDL darah (60%).Kesimpulan : Pemberian ekstrak daun bayam merah (Amaranthus tricolor L.) berpengaruh terhadap LDL darah tikus dengan dosis pemberian 200 mg/kg BB hingga 800 mg/kg BB dan HDL darah tikus dengan dosis pemberian 200 mg/kg BB hingga 400 mg/kg BB. Kata kunci : Diet Tinggi Lemak, LDL, HDL, Ekstrak Daun Bayam Merah" @default.
• W3211148132 created "2021-11-08" @default.
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• W3211148132 date "2021-10-31" @default.
• W3211148132 modified "2023-09-24" @default.
• W3211148132 title "PENGARUH PEMBERIAN EKSTRAK DAUN BAYAM MERAH (Amaranthus tricolor L.) TERHADAP KADAR LDL DAN HDL PADA TIKUS PUTIH (Rattus norvegicus) GALUR WISTAR JANTAN YANG DIBERI DIET TINGGI LEMAK" @default.
• W3211148132 doi "https://doi.org/10.33024/jkm.v7i4.4619" @default.
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