FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3211263571> ?p ?o ?g. }

• W3211263571 endingPage "1056" @default.
• W3211263571 startingPage "1051" @default.
• W3211263571 abstract "The rearrangements t(8;21)(q22;22) and inv(16)(p13q22) are two of the most frequently seen in acute myeloid leukaemia (AML), accounting for 8% and 4% of cases respectively. Detection of these abnormalities is important for disease management as both are associated with good responses to conventional chemotherapy and prolonged disease-free survival. Recent reports using reverse transcriptase polymerase chain reaction (RT-PCR) suggest that significant proportions of AML cases without a visible t(8;21) or inv(16) show expression of an abnormal fusion gene transcript and, consequently, they could not be detected using conventional cytogenetic analysis alone. We present here a four centre study involving 412 cases of AML screened using both standard cytogenetics and RT-PCR for AML1–ETO and CBFβ–MYH11. We detected a cytogenetic t(8;21) in 31 out of 412 (7·5%) cases and an inv(16) or t(16;16) variant in 27 out of 412 (6·6%) cases. RT-PCR detected only two cases (0·5%) of cryptic t(8;21) and no instances of cryptic inv(16). Both cryptic t(8;21) cases had the classic M2 FAB morphology for this type of disease. Our data concur with the established FAB type distribution of the rearrangements and indicate that cryptic t(8;21) and inv(16) may be much less frequent than reported elsewhere." @default.
• W3211263571 created "2021-11-08" @default.
• W3211263571 creator A5017554622 @default.
• W3211263571 creator A5017556550 @default.
• W3211263571 creator A5030464941 @default.
• W3211263571 creator A5034599124 @default.
• W3211263571 creator A5045977249 @default.
• W3211263571 creator A5048327114 @default.
• W3211263571 creator A5049266962 @default.
• W3211263571 creator A5058440801 @default.
• W3211263571 creator A5061362160 @default.
• W3211263571 creator A5067453135 @default.
• W3211263571 creator A5068730540 @default.
• W3211263571 creator A5079949206 @default.
• W3211263571 creator A5083734125 @default.
• W3211263571 date "2000-12-01" @default.
• W3211263571 modified "2023-10-16" @default.
• W3211263571 title "Cytogenetically cryptic AML1-ETO and CBFβ-MYH11 gene rearrangements: incidence in 412 cases of acute myeloid leukaemia" @default.
• W3211263571 cites W1524671781 @default.
• W3211263571 cites W1533510727 @default.
• W3211263571 cites W1534965621 @default.
• W3211263571 cites W1585200975 @default.
• W3211263571 cites W186058819 @default.
• W3211263571 cites W189744589 @default.
• W3211263571 cites W2005546361 @default.
• W3211263571 cites W2007495772 @default.
• W3211263571 cites W2015709946 @default.
• W3211263571 cites W2017662524 @default.
• W3211263571 cites W2036280246 @default.
• W3211263571 cites W2039992877 @default.
• W3211263571 cites W2047480444 @default.
• W3211263571 cites W2053487253 @default.
• W3211263571 cites W2068728784 @default.
• W3211263571 cites W2073200414 @default.
• W3211263571 cites W2074974156 @default.
• W3211263571 cites W2075368200 @default.
• W3211263571 cites W2089453424 @default.
• W3211263571 cites W2145713590 @default.
• W3211263571 cites W2147213204 @default.
• W3211263571 cites W2150113701 @default.
• W3211263571 cites W2280905264 @default.
• W3211263571 cites W2396904655 @default.
• W3211263571 cites W4240875696 @default.
• W3211263571 cites W4253820256 @default.
• W3211263571 doi "https://doi.org/10.1111/j.1365-2141.2000.02474.x" @default.
• W3211263571 hasPublicationYear "2000" @default.
• W3211263571 type Work @default.
• W3211263571 sameAs 3211263571 @default.
• W3211263571 citedByCount "5" @default.
• W3211263571 countsByYear W32112635712013 @default.
• W3211263571 countsByYear W32112635712018 @default.
• W3211263571 countsByYear W32112635712022 @default.
• W3211263571 crossrefType "journal-article" @default.
• W3211263571 hasAuthorship W3211263571A5017554622 @default.
• W3211263571 hasAuthorship W3211263571A5017556550 @default.
• W3211263571 hasAuthorship W3211263571A5030464941 @default.
• W3211263571 hasAuthorship W3211263571A5034599124 @default.
• W3211263571 hasAuthorship W3211263571A5045977249 @default.
• W3211263571 hasAuthorship W3211263571A5048327114 @default.
• W3211263571 hasAuthorship W3211263571A5049266962 @default.
• W3211263571 hasAuthorship W3211263571A5058440801 @default.
• W3211263571 hasAuthorship W3211263571A5061362160 @default.
• W3211263571 hasAuthorship W3211263571A5067453135 @default.
• W3211263571 hasAuthorship W3211263571A5068730540 @default.
• W3211263571 hasAuthorship W3211263571A5079949206 @default.
• W3211263571 hasAuthorship W3211263571A5083734125 @default.
• W3211263571 hasBestOaLocation W32112635711 @default.
• W3211263571 hasConcept C104317684 @default.
• W3211263571 hasConcept C111829193 @default.
• W3211263571 hasConcept C120665830 @default.
• W3211263571 hasConcept C121332964 @default.
• W3211263571 hasConcept C138626823 @default.
• W3211263571 hasConcept C153911025 @default.
• W3211263571 hasConcept C156719811 @default.
• W3211263571 hasConcept C174475383 @default.
• W3211263571 hasConcept C203014093 @default.
• W3211263571 hasConcept C2778274637 @default.
• W3211263571 hasConcept C2778729363 @default.
• W3211263571 hasConcept C2779282312 @default.
• W3211263571 hasConcept C2992511266 @default.
• W3211263571 hasConcept C30481170 @default.
• W3211263571 hasConcept C49105822 @default.
• W3211263571 hasConcept C54355233 @default.
• W3211263571 hasConcept C61511704 @default.
• W3211263571 hasConcept C86803240 @default.
• W3211263571 hasConceptScore W3211263571C104317684 @default.
• W3211263571 hasConceptScore W3211263571C111829193 @default.
• W3211263571 hasConceptScore W3211263571C120665830 @default.
• W3211263571 hasConceptScore W3211263571C121332964 @default.
• W3211263571 hasConceptScore W3211263571C138626823 @default.
• W3211263571 hasConceptScore W3211263571C153911025 @default.
• W3211263571 hasConceptScore W3211263571C156719811 @default.
• W3211263571 hasConceptScore W3211263571C174475383 @default.
• W3211263571 hasConceptScore W3211263571C203014093 @default.
• W3211263571 hasConceptScore W3211263571C2778274637 @default.
• W3211263571 hasConceptScore W3211263571C2778729363 @default.
• W3211263571 hasConceptScore W3211263571C2779282312 @default.
• W3211263571 hasConceptScore W3211263571C2992511266 @default.

• next