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- W3211435451 abstract "For developmental processes, we know most of the gene networks controlling specific cell responses. We still have to determine how these networks cooperate and how signals become integrated. The JNK pathway is one of the key elements modulating cellular responses during development. Yet, we still know little about how the core components of the pathway interact with additional regulators or how this network modulates cellular responses in the whole organism in homeostasis or during tissue morphogenesis. We have performed a promoter analysis, searching for potential regulatory sequences of puckered (puc) and identified different specific enhancers directing gene expression in different tissues and at different developmental times. Remarkably, some of these domains respond to the JNK activity, but not all. Altogether, these analyses show that puc expression regulation is very complex and that JNK activities participate in non-previously known processes during the development of Drosophila." @default.
- W3211435451 created "2021-11-22" @default.
- W3211435451 creator A5009492471 @default.
- W3211435451 creator A5042019510 @default.
- W3211435451 date "2021-11-11" @default.
- W3211435451 modified "2023-09-25" @default.
- W3211435451 title "Dissection of the Regulatory Elements of the Complex Expression Pattern of Puckered, a Dual-Specificity JNK Phosphatase" @default.
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- W3211435451 doi "https://doi.org/10.3390/ijms222212205" @default.
- W3211435451 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8623796" @default.
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- W3211435451 hasPublicationYear "2021" @default.
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