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• W3211680147 abstract "Branched-chain amino acids (BCAAs) have different immunity-related functions. Thus, BCAAs require evaluation in terms of their plasma concentration ratio. Eighty healthy participants and 57 patients with community-acquired pneumonia were enrolled. Samples from the healthy participants were collected after 12-h fasting; samples from the community-acquired pneumonia group were collected 2-3 h after lunch, during the acute (day 0) and convalescent (day 7) phases. The coefficient a of the regression line (Y = aX + b) of each BCAA plasma concentration was calculated from healthy participants and fixed, and each intercept b was calculated from the plasma concentration of each BCAA pair. Isoleucine levels increased; no significant changes in leucine concentrations were observed between healthy participants and pneumonia patients on days 0 and 7. In female participants in the pneumonia group, valine concentrations decreased on day 0. The isoleucine concentration was relatively higher than the leucine concentration on day 7 when evaluated with b. Changes in b on days 0 and 7 differed between men and women. There were sex-related differences in the plasma concentration ratios of BCAAs evaluated by b, which indicates a possible sex-related difference in the metabolic response to bacterial infection." @default.
• W3211680147 created "2021-11-22" @default.
• W3211680147 creator A5066964089 @default.
• W3211680147 date "2022-01-01" @default.
• W3211680147 modified "2023-09-25" @default.
• W3211680147 title "Changes in plasma-concentration ratios of branched-chain amino acids in acute and convalescent phases of bacterial pneumonia" @default.
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• W3211680147 doi "https://doi.org/10.3164/jcbn.21-95" @default.
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