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• W3211806559 endingPage "68" @default.
• W3211806559 startingPage "61" @default.
• W3211806559 abstract "Despite significant progress in our understanding of the etiology and pathophysiology of Hirschsprung disease (HSCR), early and accurate diagnosis and operative management can be challenging. Moreover, long-term morbidity following surgery, including fecal incontinence, constipation, and Hirschsprung-associated enterocolitis (HAEC), remains problematic. Recent advances applying state-of-the art imaging for visualization of the enteric nervous system and utilizing neuronal stem cells to replace the missing enteric neurons and glial cells offer the possibility of a promising new future for patients with HSCR. In this review, we summarize recent research advances that may one day offer novel approaches for the diagnosis and management of this disease." @default.
• W3211806559 created "2021-11-22" @default.
• W3211806559 creator A5024394546 @default.
• W3211806559 creator A5027979899 @default.
• W3211806559 creator A5088864992 @default.
• W3211806559 date "2022-09-01" @default.
• W3211806559 modified "2023-10-03" @default.
• W3211806559 title "Opportunities for novel diagnostic and cell-based therapies for Hirschsprung disease" @default.
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