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• W3211808680 abstract "This chapter reviews the approach to translating new quantitative imaging (QI) methods to clinical trials, and ultimately to clinical practice. Starting from a review of requirements for new QI tools to be ready for translation, the steps involved in clinical translation are presented. This is followed by a discussion of the type of clinical trials used to test new QI tools. Quantitative imaging biomarkers have been discussed in several chapters of this book. Here, a discussion of the cancer biomarker applications to which QI tools can be applied is presented, and specific examples of QI tools brought to clinical trials are provided. Moving tools from advanced clinical trials to clinical practice has its own challenges. Several needs and requirements for this transition are presented, followed by a summary and future directions for QI method translation." @default.
• W3211808680 created "2021-11-22" @default.
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• W3211808680 date "2021-11-12" @default.
• W3211808680 modified "2023-09-26" @default.
• W3211808680 title "Clinical Translation and Adaption" @default.
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• W3211808680 doi "https://doi.org/10.1063/9780735423558_011" @default.
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