FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3211961844> ?p ?o ?g. }

• W3211961844 endingPage "677" @default.
• W3211961844 startingPage "671" @default.
• W3211961844 abstract "For complex clinical cases where a parasitic infection is suspected, it can be difficult for clinicians to recommend an appropriate laboratory test. These tests are usually pathogen-specific and require a certain degree of suspicion for the precise etiology. A recently described assay, the universal parasite diagnostic (UPDx) can potentially provide a diagnosis of any parasite present in a specimen. Using primers that amplify DNA from all eukaryotes, UPDx differentiates several parasitic infections in blood by amplicon-based next-generation sequencing (NGS) of the 18S rDNA locus. As the state's public health reference laboratory, the Parasitology Laboratory at the Wadsworth Center (Albany, NY) receives specimens from patients who have potentially encountered a wide variety of parasites. As such, the ability to differentiate several blood parasites using a single assay is of interest. We assessed UPDx for its ability to confirm parasitic infections for 20 specimens that were previously identified by real-time PCR (RT-PCR). This included specimens positive for Babesia microti, Trypanosoma cruzi, Leishmania tropica, various Plasmodium species, and specimens comprising mixed Plasmodium sp. infections. Results obtained using UPDx were largely concordant with the RT-PCR assays. A T. cruzi positive specimen was negative by UPDx and for two mixed Plasmodium sp. infections only one species was detected. The results obtained for other specimens were concordant. We conclude that UPDx shows promise for the detection of blood parasites in diagnostic laboratories. As NGS becomes cheaper, assays like UPDx will become increasingly amenable to use in clinical settings." @default.
• W3211961844 created "2021-11-22" @default.
• W3211961844 creator A5004342536 @default.
• W3211961844 creator A5005950630 @default.
• W3211961844 creator A5020607971 @default.
• W3211961844 creator A5022996015 @default.
• W3211961844 creator A5028835317 @default.
• W3211961844 creator A5079550098 @default.
• W3211961844 creator A5090379285 @default.
• W3211961844 date "2022-02-02" @default.
• W3211961844 modified "2023-09-26" @default.
• W3211961844 title "Assessing an Adaptation of the Universal Parasite Diagnostic Assay for Bloodborne Parasites in a US State Public Health Laboratory" @default.
• W3211961844 cites W1994066209 @default.
• W3211961844 cites W2000482654 @default.
• W3211961844 cites W2027664140 @default.
• W3211961844 cites W2030202766 @default.
• W3211961844 cites W2058484100 @default.
• W3211961844 cites W2067167893 @default.
• W3211961844 cites W2069995906 @default.
• W3211961844 cites W2091849099 @default.
• W3211961844 cites W2107581952 @default.
• W3211961844 cites W2147686473 @default.
• W3211961844 cites W2151383102 @default.
• W3211961844 cites W2153352280 @default.
• W3211961844 cites W2547511573 @default.
• W3211961844 cites W2606260341 @default.
• W3211961844 cites W2891992621 @default.
• W3211961844 cites W2949066112 @default.
• W3211961844 cites W3118784002 @default.
• W3211961844 doi "https://doi.org/10.4269/ajtmh.21-0707" @default.
• W3211961844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34749306" @default.
• W3211961844 hasPublicationYear "2022" @default.
• W3211961844 type Work @default.
• W3211961844 sameAs 3211961844 @default.
• W3211961844 citedByCount "1" @default.
• W3211961844 countsByYear W32119618442023 @default.
• W3211961844 crossrefType "journal-article" @default.
• W3211961844 hasAuthorship W3211961844A5004342536 @default.
• W3211961844 hasAuthorship W3211961844A5005950630 @default.
• W3211961844 hasAuthorship W3211961844A5020607971 @default.
• W3211961844 hasAuthorship W3211961844A5022996015 @default.
• W3211961844 hasAuthorship W3211961844A5028835317 @default.
• W3211961844 hasAuthorship W3211961844A5079550098 @default.
• W3211961844 hasAuthorship W3211961844A5090379285 @default.
• W3211961844 hasBestOaLocation W32119618441 @default.
• W3211961844 hasConcept C104317684 @default.
• W3211961844 hasConcept C112418997 @default.
• W3211961844 hasConcept C136764020 @default.
• W3211961844 hasConcept C159047783 @default.
• W3211961844 hasConcept C190612196 @default.
• W3211961844 hasConcept C203014093 @default.
• W3211961844 hasConcept C2775867548 @default.
• W3211961844 hasConcept C2777625466 @default.
• W3211961844 hasConcept C2778048844 @default.
• W3211961844 hasConcept C2778371730 @default.
• W3211961844 hasConcept C2778675580 @default.
• W3211961844 hasConcept C41008148 @default.
• W3211961844 hasConcept C42972112 @default.
• W3211961844 hasConcept C49105822 @default.
• W3211961844 hasConcept C54355233 @default.
• W3211961844 hasConcept C71924100 @default.
• W3211961844 hasConcept C71928629 @default.
• W3211961844 hasConcept C8185291 @default.
• W3211961844 hasConcept C82157600 @default.
• W3211961844 hasConcept C86803240 @default.
• W3211961844 hasConcept C90856448 @default.
• W3211961844 hasConceptScore W3211961844C104317684 @default.
• W3211961844 hasConceptScore W3211961844C112418997 @default.
• W3211961844 hasConceptScore W3211961844C136764020 @default.
• W3211961844 hasConceptScore W3211961844C159047783 @default.
• W3211961844 hasConceptScore W3211961844C190612196 @default.
• W3211961844 hasConceptScore W3211961844C203014093 @default.
• W3211961844 hasConceptScore W3211961844C2775867548 @default.
• W3211961844 hasConceptScore W3211961844C2777625466 @default.
• W3211961844 hasConceptScore W3211961844C2778048844 @default.
• W3211961844 hasConceptScore W3211961844C2778371730 @default.
• W3211961844 hasConceptScore W3211961844C2778675580 @default.
• W3211961844 hasConceptScore W3211961844C41008148 @default.
• W3211961844 hasConceptScore W3211961844C42972112 @default.
• W3211961844 hasConceptScore W3211961844C49105822 @default.
• W3211961844 hasConceptScore W3211961844C54355233 @default.
• W3211961844 hasConceptScore W3211961844C71924100 @default.
• W3211961844 hasConceptScore W3211961844C71928629 @default.
• W3211961844 hasConceptScore W3211961844C8185291 @default.
• W3211961844 hasConceptScore W3211961844C82157600 @default.
• W3211961844 hasConceptScore W3211961844C86803240 @default.
• W3211961844 hasConceptScore W3211961844C90856448 @default.
• W3211961844 hasIssue "2" @default.
• W3211961844 hasLocation W32119618441 @default.
• W3211961844 hasLocation W32119618442 @default.
• W3211961844 hasLocation W32119618443 @default.
• W3211961844 hasOpenAccess W3211961844 @default.
• W3211961844 hasPrimaryLocation W32119618441 @default.
• W3211961844 hasRelatedWork W1990377559 @default.
• W3211961844 hasRelatedWork W2027533988 @default.
• W3211961844 hasRelatedWork W2115720251 @default.
• W3211961844 hasRelatedWork W2117123380 @default.
• W3211961844 hasRelatedWork W2136738350 @default.

• next