Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212121014> ?p ?o ?g. }
- W3212121014 endingPage "189" @default.
- W3212121014 startingPage "179" @default.
- W3212121014 abstract "Zaire Ebola virus (EBOV) is a member of the Filoviridae family. Infection with EBOV causes Ebola virus disease (EVD) characterized by excessive inflammation, lymphocyte death, coagulopathy, and multi-organ failure. In 2019, the FDA-approved the first anti-EBOV vaccine, rVSV-EBOV-GP (Ervebo® by Merck). This live-recombinant vaccine confers both prophylactic and therapeutic protection to nonhuman primates and humans. While mechanisms conferring prophylactic protection are well-investigated, those underlying protection conferred shortly before and after exposure to EBOV remain poorly understood. In this review, we review data from in vitro and in vivo studies analyzing early immune responses to rVSV-EBOV-GP and discuss the role of innate immune activation in therapeutic protection." @default.
- W3212121014 created "2021-11-22" @default.
- W3212121014 creator A5010470121 @default.
- W3212121014 creator A5068812777 @default.
- W3212121014 date "2021-12-01" @default.
- W3212121014 modified "2023-10-15" @default.
- W3212121014 title "Therapeutic vaccination strategies against EBOV by rVSV-EBOV-GP: the role of innate immunity" @default.
- W3212121014 cites W1603558825 @default.
- W3212121014 cites W1614627200 @default.
- W3212121014 cites W1814034318 @default.
- W3212121014 cites W1851894328 @default.
- W3212121014 cites W1966742128 @default.
- W3212121014 cites W1978479952 @default.
- W3212121014 cites W1980009575 @default.
- W3212121014 cites W1990751805 @default.
- W3212121014 cites W1996868126 @default.
- W3212121014 cites W1997001042 @default.
- W3212121014 cites W1997344007 @default.
- W3212121014 cites W1998424117 @default.
- W3212121014 cites W1998998882 @default.
- W3212121014 cites W2015999301 @default.
- W3212121014 cites W2019168201 @default.
- W3212121014 cites W2019682512 @default.
- W3212121014 cites W2019730880 @default.
- W3212121014 cites W2021377837 @default.
- W3212121014 cites W2030292647 @default.
- W3212121014 cites W2036927742 @default.
- W3212121014 cites W2038501005 @default.
- W3212121014 cites W2040453631 @default.
- W3212121014 cites W2040688497 @default.
- W3212121014 cites W2046182783 @default.
- W3212121014 cites W2046899427 @default.
- W3212121014 cites W2050813818 @default.
- W3212121014 cites W2052207335 @default.
- W3212121014 cites W2053384955 @default.
- W3212121014 cites W2060344297 @default.
- W3212121014 cites W2073132779 @default.
- W3212121014 cites W2077674909 @default.
- W3212121014 cites W2080374377 @default.
- W3212121014 cites W2083053620 @default.
- W3212121014 cites W2093141813 @default.
- W3212121014 cites W2094644220 @default.
- W3212121014 cites W2094993149 @default.
- W3212121014 cites W2099019634 @default.
- W3212121014 cites W2100827617 @default.
- W3212121014 cites W2102286438 @default.
- W3212121014 cites W2106522343 @default.
- W3212121014 cites W2106522948 @default.
- W3212121014 cites W2108394482 @default.
- W3212121014 cites W2108807439 @default.
- W3212121014 cites W2109187406 @default.
- W3212121014 cites W2109450812 @default.
- W3212121014 cites W2115174286 @default.
- W3212121014 cites W2115930490 @default.
- W3212121014 cites W2117096640 @default.
- W3212121014 cites W2120231116 @default.
- W3212121014 cites W2123674634 @default.
- W3212121014 cites W2125615308 @default.
- W3212121014 cites W2126685173 @default.
- W3212121014 cites W2128406623 @default.
- W3212121014 cites W2130268772 @default.
- W3212121014 cites W2133003848 @default.
- W3212121014 cites W2141122594 @default.
- W3212121014 cites W2146500588 @default.
- W3212121014 cites W2146986766 @default.
- W3212121014 cites W2152076520 @default.
- W3212121014 cites W2153028137 @default.
- W3212121014 cites W2153485954 @default.
- W3212121014 cites W2158734363 @default.
- W3212121014 cites W2159660583 @default.
- W3212121014 cites W2159723028 @default.
- W3212121014 cites W2161081629 @default.
- W3212121014 cites W2162358220 @default.
- W3212121014 cites W2164769880 @default.
- W3212121014 cites W2288202420 @default.
- W3212121014 cites W2293882857 @default.
- W3212121014 cites W2319030588 @default.
- W3212121014 cites W2344740792 @default.
- W3212121014 cites W2400532519 @default.
- W3212121014 cites W2414786904 @default.
- W3212121014 cites W2460973666 @default.
- W3212121014 cites W2466534784 @default.
- W3212121014 cites W2502823729 @default.
- W3212121014 cites W2507513922 @default.
- W3212121014 cites W2511385092 @default.
- W3212121014 cites W2541841360 @default.
- W3212121014 cites W2544612685 @default.
- W3212121014 cites W2564361602 @default.
- W3212121014 cites W2599269106 @default.
- W3212121014 cites W2605238696 @default.
- W3212121014 cites W2606044283 @default.
- W3212121014 cites W2607100304 @default.
- W3212121014 cites W2616989718 @default.
- W3212121014 cites W2617689720 @default.
- W3212121014 cites W2617891408 @default.
- W3212121014 cites W2624564619 @default.
- W3212121014 cites W2744632602 @default.
- W3212121014 cites W2750120956 @default.