FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212211507> ?p ?o ?g. }

• W3212211507 endingPage "5375" @default.
• W3212211507 startingPage "5375" @default.
• W3212211507 abstract "The surgical eradication of malignant glioma cells is theoretically impossible. Therefore, reducing the number of remaining tumor cells around the brain-tumor interface (BTI) is crucial for achieving satisfactory clinical results. The usefulness of fluorescence-guided resection for the treatment of malignant glioma was recently reported, but the detection of infiltrating tumor cells in the BTI using a surgical microscope is not realistic. Therefore, we have developed an intraoperative rapid fluorescence cytology system, and exploratorily evaluated its clinical feasibility for the management of malignant glioma.A total of 25 selected patients with malignant glioma (newly diagnosed: 17; recurrent: 8) underwent surgical resection under photodiagnosis using photosensitizer Talaporfin sodium and a semiconductor laser. Intraoperatively, a crush smear preparation was made from a tiny amount of tumor tissue, and the fluorescence emitted upon 620/660 nm excitation was evaluated rapidly using a compact fluorescence microscope in the operating theater.Fluorescence intensities of tumor tissues measured using a surgical microscope correlated with the tumor cell densities of tissues evaluated by measuring the red fluorescence emitted from the cytoplasm of tumor cells using a fluorescence microscope. A weak fluorescence indicated a reduction in the tumor cell density, whereas no fluorescence did not indicate the complete eradication of the tumor cells, but indicated that few tumor cells were emitting fluorescence.The rapid intraoperative detection of fluorescence from glioma cells using a compact fluorescence microscope was probably useful to evaluate the presence of tumor cells in the resection cavity walls, and could provide surgical implications for the more complete resection of malignant gliomas." @default.
• W3212211507 created "2021-11-22" @default.
• W3212211507 creator A5015110980 @default.
• W3212211507 creator A5015531938 @default.
• W3212211507 creator A5019628100 @default.
• W3212211507 creator A5087088096 @default.
• W3212211507 creator A5089897632 @default.
• W3212211507 date "2021-11-18" @default.
• W3212211507 modified "2023-09-26" @default.
• W3212211507 title "Preliminary Report: Rapid Intraoperative Detection of Residual Glioma Cell in Resection Cavity Walls Using a Compact Fluorescence Microscope" @default.
• W3212211507 cites W1523980033 @default.
• W3212211507 cites W1532262338 @default.
• W3212211507 cites W1574573897 @default.
• W3212211507 cites W1680005262 @default.
• W3212211507 cites W1792436552 @default.
• W3212211507 cites W1850380680 @default.
• W3212211507 cites W1882450096 @default.
• W3212211507 cites W1887747927 @default.
• W3212211507 cites W1964684229 @default.
• W3212211507 cites W1980719161 @default.
• W3212211507 cites W1982364032 @default.
• W3212211507 cites W1982531081 @default.
• W3212211507 cites W1983716918 @default.
• W3212211507 cites W1991872997 @default.
• W3212211507 cites W2007668137 @default.
• W3212211507 cites W2007878052 @default.
• W3212211507 cites W2012168402 @default.
• W3212211507 cites W2014265483 @default.
• W3212211507 cites W2029894128 @default.
• W3212211507 cites W2039455773 @default.
• W3212211507 cites W2042897518 @default.
• W3212211507 cites W2045165448 @default.
• W3212211507 cites W2055102924 @default.
• W3212211507 cites W2064214863 @default.
• W3212211507 cites W2077884169 @default.
• W3212211507 cites W2089488649 @default.
• W3212211507 cites W2103035005 @default.
• W3212211507 cites W2104816186 @default.
• W3212211507 cites W2125372543 @default.
• W3212211507 cites W2135282485 @default.
• W3212211507 cites W2150078661 @default.
• W3212211507 cites W2163989133 @default.
• W3212211507 cites W2166768000 @default.
• W3212211507 cites W2606489488 @default.
• W3212211507 cites W2742265809 @default.
• W3212211507 cites W2791561783 @default.
• W3212211507 cites W2914238890 @default.
• W3212211507 cites W2924811543 @default.
• W3212211507 cites W2954158150 @default.
• W3212211507 cites W3179642847 @default.
• W3212211507 doi "https://doi.org/10.3390/jcm10225375" @default.
• W3212211507 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8620805" @default.
• W3212211507 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34830662" @default.
• W3212211507 hasPublicationYear "2021" @default.
• W3212211507 type Work @default.
• W3212211507 sameAs 3212211507 @default.
• W3212211507 citedByCount "2" @default.
• W3212211507 countsByYear W32122115072023 @default.
• W3212211507 crossrefType "journal-article" @default.
• W3212211507 hasAuthorship W3212211507A5015110980 @default.
• W3212211507 hasAuthorship W3212211507A5015531938 @default.
• W3212211507 hasAuthorship W3212211507A5019628100 @default.
• W3212211507 hasAuthorship W3212211507A5087088096 @default.
• W3212211507 hasAuthorship W3212211507A5089897632 @default.
• W3212211507 hasBestOaLocation W32122115071 @default.
• W3212211507 hasConcept C120665830 @default.
• W3212211507 hasConcept C121332964 @default.
• W3212211507 hasConcept C142724271 @default.
• W3212211507 hasConcept C147080431 @default.
• W3212211507 hasConcept C169274487 @default.
• W3212211507 hasConcept C2778227246 @default.
• W3212211507 hasConcept C502942594 @default.
• W3212211507 hasConcept C67649825 @default.
• W3212211507 hasConcept C71924100 @default.
• W3212211507 hasConcept C91881484 @default.
• W3212211507 hasConceptScore W3212211507C120665830 @default.
• W3212211507 hasConceptScore W3212211507C121332964 @default.
• W3212211507 hasConceptScore W3212211507C142724271 @default.
• W3212211507 hasConceptScore W3212211507C147080431 @default.
• W3212211507 hasConceptScore W3212211507C169274487 @default.
• W3212211507 hasConceptScore W3212211507C2778227246 @default.
• W3212211507 hasConceptScore W3212211507C502942594 @default.
• W3212211507 hasConceptScore W3212211507C67649825 @default.
• W3212211507 hasConceptScore W3212211507C71924100 @default.
• W3212211507 hasConceptScore W3212211507C91881484 @default.
• W3212211507 hasIssue "22" @default.
• W3212211507 hasLocation W32122115071 @default.
• W3212211507 hasLocation W32122115072 @default.
• W3212211507 hasLocation W32122115073 @default.
• W3212211507 hasLocation W32122115074 @default.
• W3212211507 hasOpenAccess W3212211507 @default.
• W3212211507 hasPrimaryLocation W32122115071 @default.
• W3212211507 hasRelatedWork W1537873589 @default.
• W3212211507 hasRelatedWork W1549837555 @default.
• W3212211507 hasRelatedWork W1598789855 @default.
• W3212211507 hasRelatedWork W1999333779 @default.
• W3212211507 hasRelatedWork W2007543402 @default.
• W3212211507 hasRelatedWork W2023374948 @default.

• next