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• W3212328564 abstract "DNA-encoded libraries (DELs) offer great promise for the discovery of new ligands for proteins. Many current reactions used for DEL synthesis do not proceed efficiently over a wide range of substrates. Combining a diverse array of multicomponent reactions with micellar-promoted Suzuki-Miyaura cross-coupling provides a strategy for synthesizing highly diverse DELs with exceptionally high fidelity. These results demonstrate that the micellar Suzuki-Miyaura reaction has exceptional functional group tolerance and broad applicability." @default.
• W3212328564 created "2021-11-22" @default.
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• W3212328564 date "2021-11-24" @default.
• W3212328564 modified "2023-09-26" @default.
• W3212328564 title "Functional Group Tolerance of a Micellar on-DNA Suzuki–Miyaura Cross-Coupling Reaction for DNA-Encoded Library Design" @default.
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• W3212328564 doi "https://doi.org/10.1021/acs.joc.1c02259" @default.
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