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- W321243036 abstract "Primary immune deficiency diseases are inherited diseases resulting from genetic defects that affect the development or function of one or more components of the immune system, leading to an increased susceptibility to infection and, in some cases, to cancer, autoimmune or allergic disease. The main function of the immune system is protection against invading microorganisms (bacteria, viruses, fungi, and parasites) that cause disease (pathogenic microorganisms or pathogens). In addition, it must destroy any of the body's own cells that develop into cancer. The genetic defects that alter any of the components of the immune system result in an enhanced susceptibility to infection and in some cases, an inability to kill cancer cells or a dysregulation of the immune system leading to autoimmune or allergic disease. These immunodeficiency diseases demonstrate the importance of each of the altered components of the immune system. This article describes some of the known genetic immunodeficiency diseases, each of which illustrates the role of different molecules and cell populations in immunity." @default.
- W321243036 created "2016-06-24" @default.
- W321243036 creator A5047049034 @default.
- W321243036 date "2014-01-01" @default.
- W321243036 modified "2023-09-27" @default.
- W321243036 title "Human Primary Immunodeficiencies" @default.
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- W321243036 doi "https://doi.org/10.1016/b978-0-12-801238-3.00122-7" @default.
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