FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212478730> ?p ?o ?g. }

• W3212478730 endingPage "106023" @default.
• W3212478730 startingPage "106023" @default.
• W3212478730 abstract "Although both vitamin D deficiency and obesity are highly prevalent in the UAE, the role of vitamin D metabolites in mediating obesity-related adverse health effects is not clear. We aimed to assess the role of vitamin D metabolites as potential mediators in the association between obesity, inflammation and metabolic risk factors.277 participants who were part of a randomized controlled trial had their assessment that included clinical, anthropometric and physical activity data at baseline and at 6 months. Blood and urine samples were taken for measurements of serum 25(OH)D, 25(OH)D metabolites including 25(OH)D3), 25(OH)D2), 1,25(OH)2D3, 3-Epi-D3), metabolic and inflammatory markers and related biochemical variables. Multiple regression analysis used to assess the role of 25(OH)D metabolites in mediating the effect of increasing body mass index (BMI) on inflammation and metabolic risk factors.Overall, 277 participants with complete 6 months follow up with a mean (±SD) age of 41 ± 12 and 204 (74%) female were included in the study. Blood pressure, inflammatory, metabolic and lipid profile markers significantly increased in overweight and obese subjects compared to subjects with normal BMI both at baseline and at 6 months (p < 0.05). 25(OH)D revealed significant association with age, gender, HbA1c and type 2 diabetes (p < 0.05). No statistically significant changes in any of 25(OH)D metabolites assessed. Multivariate analysis revealed significant and independent associations between BMI and important inflammatory and metabolic risk factors (p < 0.05). No similar association observed with 25(OH)D metabolites.Although we found significant association between 25(OH)D and prevalence of type 2 diabetes, we found no evidence however to support a role of 25(OH)D metabolites in mediating the effect of BMI on inflammatory or metabolic risk factors." @default.
• W3212478730 created "2021-11-22" @default.
• W3212478730 creator A5001515790 @default.
• W3212478730 creator A5058344417 @default.
• W3212478730 creator A5065018778 @default.
• W3212478730 creator A5069128871 @default.
• W3212478730 date "2022-01-01" @default.
• W3212478730 modified "2023-09-30" @default.
• W3212478730 title "Vitamin D [25(OH)D] metabolites and epimers in obese subject: Interaction and correlations with adverse metabolic health risk factors" @default.
• W3212478730 cites W1964198697 @default.
• W3212478730 cites W1967386430 @default.
• W3212478730 cites W1980897423 @default.
• W3212478730 cites W1991736636 @default.
• W3212478730 cites W2042264409 @default.
• W3212478730 cites W2092450600 @default.
• W3212478730 cites W2109509305 @default.
• W3212478730 cites W2109726000 @default.
• W3212478730 cites W2117706634 @default.
• W3212478730 cites W2122945494 @default.
• W3212478730 cites W2137528384 @default.
• W3212478730 cites W2153372980 @default.
• W3212478730 cites W2183392429 @default.
• W3212478730 cites W229236060 @default.
• W3212478730 cites W2578853902 @default.
• W3212478730 cites W2793715941 @default.
• W3212478730 cites W2891363291 @default.
• W3212478730 cites W2895313196 @default.
• W3212478730 cites W2910974504 @default.
• W3212478730 cites W2947268657 @default.
• W3212478730 cites W2948994757 @default.
• W3212478730 cites W2980008083 @default.
• W3212478730 cites W2998808413 @default.
• W3212478730 cites W3013984341 @default.
• W3212478730 cites W3090780683 @default.
• W3212478730 cites W3112309355 @default.
• W3212478730 cites W3165273823 @default.
• W3212478730 cites W798202581 @default.
• W3212478730 doi "https://doi.org/10.1016/j.jsbmb.2021.106023" @default.
• W3212478730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34774725" @default.
• W3212478730 hasPublicationYear "2022" @default.
• W3212478730 type Work @default.
• W3212478730 sameAs 3212478730 @default.
• W3212478730 citedByCount "4" @default.
• W3212478730 countsByYear W32124787302022 @default.
• W3212478730 countsByYear W32124787302023 @default.
• W3212478730 crossrefType "journal-article" @default.
• W3212478730 hasAuthorship W3212478730A5001515790 @default.
• W3212478730 hasAuthorship W3212478730A5058344417 @default.
• W3212478730 hasAuthorship W3212478730A5065018778 @default.
• W3212478730 hasAuthorship W3212478730A5069128871 @default.
• W3212478730 hasConcept C124490489 @default.
• W3212478730 hasConcept C126322002 @default.
• W3212478730 hasConcept C134018914 @default.
• W3212478730 hasConcept C197934379 @default.
• W3212478730 hasConcept C2776940978 @default.
• W3212478730 hasConcept C2780221984 @default.
• W3212478730 hasConcept C2780578515 @default.
• W3212478730 hasConcept C2780586474 @default.
• W3212478730 hasConcept C42407357 @default.
• W3212478730 hasConcept C511355011 @default.
• W3212478730 hasConcept C71924100 @default.
• W3212478730 hasConceptScore W3212478730C124490489 @default.
• W3212478730 hasConceptScore W3212478730C126322002 @default.
• W3212478730 hasConceptScore W3212478730C134018914 @default.
• W3212478730 hasConceptScore W3212478730C197934379 @default.
• W3212478730 hasConceptScore W3212478730C2776940978 @default.
• W3212478730 hasConceptScore W3212478730C2780221984 @default.
• W3212478730 hasConceptScore W3212478730C2780578515 @default.
• W3212478730 hasConceptScore W3212478730C2780586474 @default.
• W3212478730 hasConceptScore W3212478730C42407357 @default.
• W3212478730 hasConceptScore W3212478730C511355011 @default.
• W3212478730 hasConceptScore W3212478730C71924100 @default.
• W3212478730 hasFunder F4320323593 @default.
• W3212478730 hasFunder F4320335082 @default.
• W3212478730 hasLocation W32124787301 @default.
• W3212478730 hasLocation W32124787302 @default.
• W3212478730 hasOpenAccess W3212478730 @default.
• W3212478730 hasPrimaryLocation W32124787301 @default.
• W3212478730 hasRelatedWork W1866091461 @default.
• W3212478730 hasRelatedWork W1903601530 @default.
• W3212478730 hasRelatedWork W2000335303 @default.
• W3212478730 hasRelatedWork W2047277250 @default.
• W3212478730 hasRelatedWork W2363570094 @default.
• W3212478730 hasRelatedWork W2403825624 @default.
• W3212478730 hasRelatedWork W2625095604 @default.
• W3212478730 hasRelatedWork W2777447650 @default.
• W3212478730 hasRelatedWork W4380150467 @default.
• W3212478730 hasRelatedWork W8959992 @default.
• W3212478730 hasVolume "215" @default.
• W3212478730 isParatext "false" @default.
• W3212478730 isRetracted "false" @default.
• W3212478730 magId "3212478730" @default.
• W3212478730 workType "article" @default.