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- W3212492724 abstract "The objective of this research was to analyze the protective effect of indole-3-carbinol against the stomach injury induced by acetylsalicylic acid. Male rats were randomly divided into eight groups of six animals in each group. Control group, OMP group, I3C group, OMP+I3C group, AA group, AA+OMP group, AA+I3C group, and AA+OMP+I3C group. The control rats were received distilled water and the experimental rats were received AA at a dose of 500 mg/kg body weight, OMP at a dose of 20 mg/kg body weight, and I3C at a dose of 50 mg/kg body weight either alone or in combination with each other, orally for seven consecutive days. Results of the present study showed ulcer protection in indole-3-cabinol treated rats was confirmed by histoarchitecture, which was comprised of the reduced size of ulcer crater and restoration of mucosal epithelium. Thus, reduced neutrophil infiltration, antiapoptotic and antioxidant action have a pivotal role in the gastroprotective effect of indole-3-carbinol. Keywords: Histopathological; Stomach; Acetylsalicylic acid; Indole-3-carbinol; Rats" @default.
- W3212492724 created "2021-11-22" @default.
- W3212492724 creator A5031313887 @default.
- W3212492724 date "2021-08-25" @default.
- W3212492724 modified "2023-09-26" @default.
- W3212492724 title "The Protective Effects of Indole-3-carbinol on Stomach Injury in Rats" @default.
- W3212492724 doi "https://doi.org/10.36811/ljbs.2021.110070" @default.
- W3212492724 hasPublicationYear "2021" @default.
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