FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212496640> ?p ?o ?g. }

• W3212496640 endingPage "76" @default.
• W3212496640 startingPage "71" @default.
• W3212496640 abstract "Severe aortic stenosis (AS) is often characterized by myocardial interstitial fibrosis. Myocardial interstitial fibrosis, classically measured by magnetic resonance imaging, was also shown to be accurately measured by computed tomography (CT)-derived extracellular volume fraction (ECVF). Serum albumin (SA) level (g/dl) has been shown to correlate with ECVF among patients with heart failure and preserved ejection fraction. Our objective was to evaluate the association between SA and ECVF among patients with severe symptomatic AS. Patients with symptomatic severe AS who were evaluated as candidates for intervention between 2016 and 2018 were enrolled prospectively. All patients underwent precontrast and postcontrast CT for estimating myocardial ECVF. Valid ambulatory SA within 6 weeks of the cardiac CT were obtained and classified as (tertiles) <3.8, 3.8 to 4.19, and ≥4.2 g/dl. Patients with acute systemic illness at the time of the albumin test were excluded. The study included 68 patients, mean age 81 ± 6 years, 53% women. Patients with lower SA were more likely to have chronic renal failure, previous percutaneous coronary interventions, and a reduced functional class. The mean ECVF (%) in the study cohort was 41 ± 12%, significantly higher among the patients in the lower SA level groups (50 ± 12% vs 38 ± 7% vs 33 ± 9% in the <3.8 g/dl, 3.8 to 4.19 g/dl and ≥4.2 g/dl groups respectively, p for trend <0.001). A statistically significant inverse correlation was found between SA levels and ECVF (r −0.7, p <0.001). Multivariable analysis showed significant independent association between low SA and ECVF. In conclusion, the SA level is inversely associated with CT-derived ECVF in patients with severe AS. Severe aortic stenosis (AS) is often characterized by myocardial interstitial fibrosis. Myocardial interstitial fibrosis, classically measured by magnetic resonance imaging, was also shown to be accurately measured by computed tomography (CT)-derived extracellular volume fraction (ECVF). Serum albumin (SA) level (g/dl) has been shown to correlate with ECVF among patients with heart failure and preserved ejection fraction. Our objective was to evaluate the association between SA and ECVF among patients with severe symptomatic AS. Patients with symptomatic severe AS who were evaluated as candidates for intervention between 2016 and 2018 were enrolled prospectively. All patients underwent precontrast and postcontrast CT for estimating myocardial ECVF. Valid ambulatory SA within 6 weeks of the cardiac CT were obtained and classified as (tertiles) <3.8, 3.8 to 4.19, and ≥4.2 g/dl. Patients with acute systemic illness at the time of the albumin test were excluded. The study included 68 patients, mean age 81 ± 6 years, 53% women. Patients with lower SA were more likely to have chronic renal failure, previous percutaneous coronary interventions, and a reduced functional class. The mean ECVF (%) in the study cohort was 41 ± 12%, significantly higher among the patients in the lower SA level groups (50 ± 12% vs 38 ± 7% vs 33 ± 9% in the <3.8 g/dl, 3.8 to 4.19 g/dl and ≥4.2 g/dl groups respectively, p for trend <0.001). A statistically significant inverse correlation was found between SA levels and ECVF (r −0.7, p <0.001). Multivariable analysis showed significant independent association between low SA and ECVF. In conclusion, the SA level is inversely associated with CT-derived ECVF in patients with severe AS." @default.
• W3212496640 created "2021-11-22" @default.
• W3212496640 creator A5017657656 @default.
• W3212496640 creator A5028079332 @default.
• W3212496640 creator A5036710578 @default.
• W3212496640 creator A5039021929 @default.
• W3212496640 creator A5039789130 @default.
• W3212496640 creator A5041314036 @default.
• W3212496640 creator A5049278377 @default.
• W3212496640 creator A5051776383 @default.
• W3212496640 creator A5082629418 @default.
• W3212496640 date "2022-01-01" @default.
• W3212496640 modified "2023-09-27" @default.
• W3212496640 title "Relation of Serum Albumin Levels to Myocardial Extracellular Volume in Patients With Severe Aortic Stenosis" @default.
• W3212496640 cites W173091792 @default.
• W3212496640 cites W1809056726 @default.
• W3212496640 cites W1974796215 @default.
• W3212496640 cites W1983330058 @default.
• W3212496640 cites W1983338129 @default.
• W3212496640 cites W2007790334 @default.
• W3212496640 cites W2025383517 @default.
• W3212496640 cites W2027082110 @default.
• W3212496640 cites W2035446068 @default.
• W3212496640 cites W2102775774 @default.
• W3212496640 cites W2120095987 @default.
• W3212496640 cites W2123124648 @default.
• W3212496640 cites W2136811556 @default.
• W3212496640 cites W2180244730 @default.
• W3212496640 cites W2317184793 @default.
• W3212496640 cites W2460608843 @default.
• W3212496640 cites W2567057146 @default.
• W3212496640 cites W2736888189 @default.
• W3212496640 cites W2767726095 @default.
• W3212496640 cites W2792619404 @default.
• W3212496640 cites W2800769506 @default.
• W3212496640 cites W2944335205 @default.
• W3212496640 cites W2973749867 @default.
• W3212496640 cites W2990724953 @default.
• W3212496640 cites W3000710027 @default.
• W3212496640 cites W3005476393 @default.
• W3212496640 cites W3089713237 @default.
• W3212496640 cites W3112747434 @default.
• W3212496640 cites W3135510918 @default.
• W3212496640 cites W3157543224 @default.
• W3212496640 doi "https://doi.org/10.1016/j.amjcard.2021.09.044" @default.
• W3212496640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34772478" @default.
• W3212496640 hasPublicationYear "2022" @default.
• W3212496640 type Work @default.
• W3212496640 sameAs 3212496640 @default.
• W3212496640 citedByCount "0" @default.
• W3212496640 crossrefType "journal-article" @default.
• W3212496640 hasAuthorship W3212496640A5017657656 @default.
• W3212496640 hasAuthorship W3212496640A5028079332 @default.
• W3212496640 hasAuthorship W3212496640A5036710578 @default.
• W3212496640 hasAuthorship W3212496640A5039021929 @default.
• W3212496640 hasAuthorship W3212496640A5039789130 @default.
• W3212496640 hasAuthorship W3212496640A5041314036 @default.
• W3212496640 hasAuthorship W3212496640A5049278377 @default.
• W3212496640 hasAuthorship W3212496640A5051776383 @default.
• W3212496640 hasAuthorship W3212496640A5082629418 @default.
• W3212496640 hasConcept C126322002 @default.
• W3212496640 hasConcept C126838900 @default.
• W3212496640 hasConcept C143409427 @default.
• W3212496640 hasConcept C164705383 @default.
• W3212496640 hasConcept C2778198053 @default.
• W3212496640 hasConcept C2780007028 @default.
• W3212496640 hasConcept C2780559512 @default.
• W3212496640 hasConcept C3018763269 @default.
• W3212496640 hasConcept C35785553 @default.
• W3212496640 hasConcept C71924100 @default.
• W3212496640 hasConcept C78085059 @default.
• W3212496640 hasConceptScore W3212496640C126322002 @default.
• W3212496640 hasConceptScore W3212496640C126838900 @default.
• W3212496640 hasConceptScore W3212496640C143409427 @default.
• W3212496640 hasConceptScore W3212496640C164705383 @default.
• W3212496640 hasConceptScore W3212496640C2778198053 @default.
• W3212496640 hasConceptScore W3212496640C2780007028 @default.
• W3212496640 hasConceptScore W3212496640C2780559512 @default.
• W3212496640 hasConceptScore W3212496640C3018763269 @default.
• W3212496640 hasConceptScore W3212496640C35785553 @default.
• W3212496640 hasConceptScore W3212496640C71924100 @default.
• W3212496640 hasConceptScore W3212496640C78085059 @default.
• W3212496640 hasLocation W32124966401 @default.
• W3212496640 hasLocation W32124966402 @default.
• W3212496640 hasOpenAccess W3212496640 @default.
• W3212496640 hasPrimaryLocation W32124966401 @default.
• W3212496640 hasRelatedWork W1660427814 @default.
• W3212496640 hasRelatedWork W2051712573 @default.
• W3212496640 hasRelatedWork W2091139515 @default.
• W3212496640 hasRelatedWork W2319805938 @default.
• W3212496640 hasRelatedWork W2322527785 @default.
• W3212496640 hasRelatedWork W2355594703 @default.
• W3212496640 hasRelatedWork W3033076790 @default.
• W3212496640 hasRelatedWork W3155674270 @default.
• W3212496640 hasRelatedWork W3187572025 @default.
• W3212496640 hasRelatedWork W4367182379 @default.
• W3212496640 hasVolume "163" @default.
• W3212496640 isParatext "false" @default.

• next