Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212864216> ?p ?o ?g. }
- W3212864216 endingPage "3068" @default.
- W3212864216 startingPage "3068" @default.
- W3212864216 abstract "The surface charge of iron oxide nanoparticles (IONPs) plays a critical role in the interactions between nanoparticles and biological components, which significantly affects their toxicity in vitro and in vivo. In this study, we synthesized three differently charged IONPs (negative, neutral, and positive) based on catechol-derived dopamine, polyethylene glycol, carboxylic acid, and amine groups, via reversible addition-fragmentation chain transfer-mediated polymerization (RAFT polymerization) and ligand exchange. The zeta potentials of the negative, neutral, and positive IONPs were -39, -0.6, and +32 mV, respectively, and all three IONPs showed long-term colloidal stability for three months in an aqueous solution without agglomeration. The cytotoxicity of the IONPs was studied by analyzing cell viability and morphological alteration in three human cell lines, A549, Huh-7, and SH-SY5Y. Neither IONP caused significant cellular damage in any of the three cell lines. Furthermore, the IONPs showed no acute toxicity in BALB/c mice, in hematological and histological analyses. These results indicate that our charged IONPs, having high colloidal stability and biocompatibility, are viable for bio-applications." @default.
- W3212864216 created "2021-11-22" @default.
- W3212864216 creator A5003417874 @default.
- W3212864216 creator A5006602557 @default.
- W3212864216 creator A5022948394 @default.
- W3212864216 creator A5035147466 @default.
- W3212864216 creator A5068092189 @default.
- W3212864216 creator A5083116678 @default.
- W3212864216 creator A5086898573 @default.
- W3212864216 date "2021-11-14" @default.
- W3212864216 modified "2023-10-07" @default.
- W3212864216 title "Charge-Modulated Synthesis of Highly Stable Iron Oxide Nanoparticles for In Vitro and In Vivo Toxicity Evaluation" @default.
- W3212864216 cites W1900489562 @default.
- W3212864216 cites W1914561039 @default.
- W3212864216 cites W1966805498 @default.
- W3212864216 cites W1972835273 @default.
- W3212864216 cites W1975523244 @default.
- W3212864216 cites W1986156969 @default.
- W3212864216 cites W1996242594 @default.
- W3212864216 cites W2001071466 @default.
- W3212864216 cites W2013855421 @default.
- W3212864216 cites W2026691184 @default.
- W3212864216 cites W2027876233 @default.
- W3212864216 cites W2029871153 @default.
- W3212864216 cites W2043400217 @default.
- W3212864216 cites W2047571912 @default.
- W3212864216 cites W2052609925 @default.
- W3212864216 cites W2059002480 @default.
- W3212864216 cites W2075741216 @default.
- W3212864216 cites W2085231987 @default.
- W3212864216 cites W2089732214 @default.
- W3212864216 cites W2097338689 @default.
- W3212864216 cites W2107708565 @default.
- W3212864216 cites W2118969052 @default.
- W3212864216 cites W2126346850 @default.
- W3212864216 cites W2153287190 @default.
- W3212864216 cites W2158491789 @default.
- W3212864216 cites W2220432301 @default.
- W3212864216 cites W2299520011 @default.
- W3212864216 cites W2315737460 @default.
- W3212864216 cites W2328002971 @default.
- W3212864216 cites W2344643292 @default.
- W3212864216 cites W2591295489 @default.
- W3212864216 cites W2760301900 @default.
- W3212864216 cites W2791467515 @default.
- W3212864216 cites W2805521463 @default.
- W3212864216 cites W3086338668 @default.
- W3212864216 cites W3195473935 @default.
- W3212864216 cites W3199415261 @default.
- W3212864216 cites W3199669985 @default.
- W3212864216 cites W3200911723 @default.
- W3212864216 cites W3207663493 @default.
- W3212864216 doi "https://doi.org/10.3390/nano11113068" @default.
- W3212864216 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8624538" @default.
- W3212864216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34835832" @default.
- W3212864216 hasPublicationYear "2021" @default.
- W3212864216 type Work @default.
- W3212864216 sameAs 3212864216 @default.
- W3212864216 citedByCount "7" @default.
- W3212864216 countsByYear W32128642162022 @default.
- W3212864216 countsByYear W32128642162023 @default.
- W3212864216 crossrefType "journal-article" @default.
- W3212864216 hasAuthorship W3212864216A5003417874 @default.
- W3212864216 hasAuthorship W3212864216A5006602557 @default.
- W3212864216 hasAuthorship W3212864216A5022948394 @default.
- W3212864216 hasAuthorship W3212864216A5035147466 @default.
- W3212864216 hasAuthorship W3212864216A5068092189 @default.
- W3212864216 hasAuthorship W3212864216A5083116678 @default.
- W3212864216 hasAuthorship W3212864216A5086898573 @default.
- W3212864216 hasBestOaLocation W32128642161 @default.
- W3212864216 hasConcept C109316439 @default.
- W3212864216 hasConcept C12554922 @default.
- W3212864216 hasConcept C147789679 @default.
- W3212864216 hasConcept C150903083 @default.
- W3212864216 hasConcept C155672457 @default.
- W3212864216 hasConcept C171250308 @default.
- W3212864216 hasConcept C178790620 @default.
- W3212864216 hasConcept C185592680 @default.
- W3212864216 hasConcept C192562407 @default.
- W3212864216 hasConcept C202751555 @default.
- W3212864216 hasConcept C207001950 @default.
- W3212864216 hasConcept C2776964284 @default.
- W3212864216 hasConcept C2777230088 @default.
- W3212864216 hasConcept C2777697756 @default.
- W3212864216 hasConcept C2778889443 @default.
- W3212864216 hasConcept C2780358262 @default.
- W3212864216 hasConcept C44228677 @default.
- W3212864216 hasConcept C521977710 @default.
- W3212864216 hasConcept C53227056 @default.
- W3212864216 hasConcept C55493867 @default.
- W3212864216 hasConcept C86181022 @default.
- W3212864216 hasConcept C86803240 @default.
- W3212864216 hasConceptScore W3212864216C109316439 @default.
- W3212864216 hasConceptScore W3212864216C12554922 @default.
- W3212864216 hasConceptScore W3212864216C147789679 @default.
- W3212864216 hasConceptScore W3212864216C150903083 @default.
- W3212864216 hasConceptScore W3212864216C155672457 @default.
- W3212864216 hasConceptScore W3212864216C171250308 @default.