Matches in SemOpenAlex for { <https://semopenalex.org/work/W3212912059> ?p ?o ?g. }
- W3212912059 endingPage "100942" @default.
- W3212912059 startingPage "100942" @default.
- W3212912059 abstract "The heterogeneity and plasticity of muscle fibers are essential for the athletic performance of horses, mainly at the adaption of exercises and the effect on muscle diseases. Skeletal muscle fibers can be generally distinguished by their characteristics of contraction as slow and fast type myofibers. The diversity of contractile properties and metabolism enable skeletal muscles to respond to the variable functional requirements. We investigated the muscle fiber composition and metabolic enzyme activities of splenius muscle and gluteus medius muscle from Mongolian horses. The deep RNA-seq analysis of detecting differentially expressed mRNAs, lncRNAs, circRNAs and their correlation analysis from two muscles were performed. Splenius muscle and gluteus medius muscle from Mongolian horses showed a high divergence of myofiber compositions and metabolic enzyme activities. Corresponding to their phenotypic characteristics, 57 differentially expressed long noncoding RNAs and 12 differentially expressed circle RNAs were found between two muscles. The analysis results indicate multiple binding sites were detected in lncRNAs and circRNAs with myofiber-specific expressed miRNAs. Among which we found significant correlations between the above noncoding RNAs, miRNAs, their target genes, myofiber-specific developmental transcript factors, and sarcomere genes. We suggest that the ceRNA mechanism of differentially expressed noncoding RNAs by acting as miRNA sponges could be fine tuners in regulating skeletal muscle fiber composition and transition in horses, which will operate new protective measures of muscle disease and locomotor adaption for racehorses." @default.
- W3212912059 created "2021-11-22" @default.
- W3212912059 creator A5009451649 @default.
- W3212912059 creator A5027008179 @default.
- W3212912059 creator A5036029346 @default.
- W3212912059 creator A5039112913 @default.
- W3212912059 creator A5040781418 @default.
- W3212912059 creator A5040947460 @default.
- W3212912059 creator A5065649710 @default.
- W3212912059 creator A5068016541 @default.
- W3212912059 creator A5072275433 @default.
- W3212912059 creator A5072277102 @default.
- W3212912059 creator A5080867678 @default.
- W3212912059 creator A5085279249 @default.
- W3212912059 date "2022-03-01" @default.
- W3212912059 modified "2023-09-26" @default.
- W3212912059 title "Fast and slow myofiber-specific expression profiles are affected by noncoding RNAs in Mongolian horses" @default.
- W3212912059 cites W1775951641 @default.
- W3212912059 cites W1985130783 @default.
- W3212912059 cites W1987131090 @default.
- W3212912059 cites W1989862163 @default.
- W3212912059 cites W1994264655 @default.
- W3212912059 cites W2001548627 @default.
- W3212912059 cites W2036897871 @default.
- W3212912059 cites W2045736879 @default.
- W3212912059 cites W2045938670 @default.
- W3212912059 cites W2048194168 @default.
- W3212912059 cites W2054919793 @default.
- W3212912059 cites W2058835062 @default.
- W3212912059 cites W2061548680 @default.
- W3212912059 cites W2067786443 @default.
- W3212912059 cites W2068277549 @default.
- W3212912059 cites W2068837990 @default.
- W3212912059 cites W2074248426 @default.
- W3212912059 cites W2077112328 @default.
- W3212912059 cites W2090642023 @default.
- W3212912059 cites W2097649488 @default.
- W3212912059 cites W2099999808 @default.
- W3212912059 cites W2102278945 @default.
- W3212912059 cites W2108966129 @default.
- W3212912059 cites W2120456037 @default.
- W3212912059 cites W2125776406 @default.
- W3212912059 cites W2130025116 @default.
- W3212912059 cites W2130687298 @default.
- W3212912059 cites W2134193049 @default.
- W3212912059 cites W2134629862 @default.
- W3212912059 cites W2145931730 @default.
- W3212912059 cites W2148199891 @default.
- W3212912059 cites W2159675211 @default.
- W3212912059 cites W2164713351 @default.
- W3212912059 cites W2179438025 @default.
- W3212912059 cites W2464424326 @default.
- W3212912059 cites W2514724102 @default.
- W3212912059 cites W2522907865 @default.
- W3212912059 cites W2599812844 @default.
- W3212912059 cites W2607796168 @default.
- W3212912059 cites W2615786037 @default.
- W3212912059 cites W2765730818 @default.
- W3212912059 cites W2768941193 @default.
- W3212912059 cites W2791574629 @default.
- W3212912059 cites W2799541123 @default.
- W3212912059 cites W2889101109 @default.
- W3212912059 cites W2890460146 @default.
- W3212912059 cites W2892137891 @default.
- W3212912059 cites W2898118377 @default.
- W3212912059 cites W2900163929 @default.
- W3212912059 cites W2936212010 @default.
- W3212912059 cites W296898222 @default.
- W3212912059 cites W2984285153 @default.
- W3212912059 cites W2995527562 @default.
- W3212912059 cites W3138909083 @default.
- W3212912059 cites W4293767581 @default.
- W3212912059 doi "https://doi.org/10.1016/j.cbd.2021.100942" @default.
- W3212912059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34823143" @default.
- W3212912059 hasPublicationYear "2022" @default.
- W3212912059 type Work @default.
- W3212912059 sameAs 3212912059 @default.
- W3212912059 citedByCount "1" @default.
- W3212912059 countsByYear W32129120592022 @default.
- W3212912059 crossrefType "journal-article" @default.
- W3212912059 hasAuthorship W3212912059A5009451649 @default.
- W3212912059 hasAuthorship W3212912059A5027008179 @default.
- W3212912059 hasAuthorship W3212912059A5036029346 @default.
- W3212912059 hasAuthorship W3212912059A5039112913 @default.
- W3212912059 hasAuthorship W3212912059A5040781418 @default.
- W3212912059 hasAuthorship W3212912059A5040947460 @default.
- W3212912059 hasAuthorship W3212912059A5065649710 @default.
- W3212912059 hasAuthorship W3212912059A5068016541 @default.
- W3212912059 hasAuthorship W3212912059A5072275433 @default.
- W3212912059 hasAuthorship W3212912059A5072277102 @default.
- W3212912059 hasAuthorship W3212912059A5080867678 @default.
- W3212912059 hasAuthorship W3212912059A5085279249 @default.
- W3212912059 hasConcept C104317684 @default.
- W3212912059 hasConcept C105702510 @default.
- W3212912059 hasConcept C127716648 @default.
- W3212912059 hasConcept C145059251 @default.
- W3212912059 hasConcept C150194340 @default.
- W3212912059 hasConcept C162317418 @default.