Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213017895> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3213017895 endingPage "4756" @default.
- W3213017895 startingPage "4751" @default.
- W3213017895 abstract "Curcuma singularis Gagnep is a Vietnamese medicinal plant which has been commonly used in traditional and folk medicines for the treatment of different diseases. The goals of the present study are to investigate chemical composition and anti-proliferative activity of Curcuma singularis rhizome extract (CSE). The in vitro cytotoxicity of CSE was evaluated using WST-1 and LDH assays. The apoptosis induction was determined using nuclei DAPI staining and FACS assays. The main compounds of extract were identified and quantitatively analyzed using the validated HPLC method. The extract showed cytotoxic effects in various liver and breast cancer cells but had minimal effects on normal cells. It induced apoptosis on both Hep3B and SKBR3 cells in a dose-dependent manner. In addition, three sesquiterpene compounds, such as germacrone (3.25 ± 0.32 mg/g), ar-turmerone (1.12 ± 0.24 mg/g), and curcumol (0.31 ± 0.12 mg/g) were found as the main components of CSE. This is the first report on the in vitro cytotoxic effect of Curcuma singularis rhizomes against cancer cells." @default.
- W3213017895 created "2021-11-22" @default.
- W3213017895 creator A5006496190 @default.
- W3213017895 creator A5020833933 @default.
- W3213017895 creator A5025723093 @default.
- W3213017895 creator A5029329883 @default.
- W3213017895 creator A5045826726 @default.
- W3213017895 creator A5060311920 @default.
- W3213017895 creator A5064371685 @default.
- W3213017895 creator A5070759315 @default.
- W3213017895 creator A5077864512 @default.
- W3213017895 creator A5088651556 @default.
- W3213017895 date "2021-11-18" @default.
- W3213017895 modified "2023-09-23" @default.
- W3213017895 title "Investigation of bioactive chemical constituents and anti-cancer activity of ethanol extract of <i>Curcuma singularis</i> Gagnep rhizomes" @default.
- W3213017895 cites W1937118646 @default.
- W3213017895 cites W1985239808 @default.
- W3213017895 cites W2006328466 @default.
- W3213017895 cites W2008757142 @default.
- W3213017895 cites W2042714987 @default.
- W3213017895 cites W2059008362 @default.
- W3213017895 cites W2075339470 @default.
- W3213017895 cites W2087580878 @default.
- W3213017895 cites W2089490944 @default.
- W3213017895 cites W2102338652 @default.
- W3213017895 cites W2140316468 @default.
- W3213017895 cites W2161325793 @default.
- W3213017895 cites W2161845004 @default.
- W3213017895 cites W2336467840 @default.
- W3213017895 cites W2355299061 @default.
- W3213017895 cites W2579569650 @default.
- W3213017895 cites W2772652039 @default.
- W3213017895 cites W2782022622 @default.
- W3213017895 cites W2790067038 @default.
- W3213017895 cites W2809828975 @default.
- W3213017895 cites W2888926122 @default.
- W3213017895 cites W4241052211 @default.
- W3213017895 doi "https://doi.org/10.1080/14786419.2021.2005595" @default.
- W3213017895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34794366" @default.
- W3213017895 hasPublicationYear "2021" @default.
- W3213017895 type Work @default.
- W3213017895 sameAs 3213017895 @default.
- W3213017895 citedByCount "3" @default.
- W3213017895 countsByYear W32130178952023 @default.
- W3213017895 crossrefType "journal-article" @default.
- W3213017895 hasAuthorship W3213017895A5006496190 @default.
- W3213017895 hasAuthorship W3213017895A5020833933 @default.
- W3213017895 hasAuthorship W3213017895A5025723093 @default.
- W3213017895 hasAuthorship W3213017895A5029329883 @default.
- W3213017895 hasAuthorship W3213017895A5045826726 @default.
- W3213017895 hasAuthorship W3213017895A5060311920 @default.
- W3213017895 hasAuthorship W3213017895A5064371685 @default.
- W3213017895 hasAuthorship W3213017895A5070759315 @default.
- W3213017895 hasAuthorship W3213017895A5077864512 @default.
- W3213017895 hasAuthorship W3213017895A5088651556 @default.
- W3213017895 hasConcept C109316439 @default.
- W3213017895 hasConcept C134550120 @default.
- W3213017895 hasConcept C154317977 @default.
- W3213017895 hasConcept C185592680 @default.
- W3213017895 hasConcept C190283241 @default.
- W3213017895 hasConcept C202751555 @default.
- W3213017895 hasConcept C2776789170 @default.
- W3213017895 hasConcept C2777230291 @default.
- W3213017895 hasConcept C55493867 @default.
- W3213017895 hasConcept C556039675 @default.
- W3213017895 hasConcept C71924100 @default.
- W3213017895 hasConceptScore W3213017895C109316439 @default.
- W3213017895 hasConceptScore W3213017895C134550120 @default.
- W3213017895 hasConceptScore W3213017895C154317977 @default.
- W3213017895 hasConceptScore W3213017895C185592680 @default.
- W3213017895 hasConceptScore W3213017895C190283241 @default.
- W3213017895 hasConceptScore W3213017895C202751555 @default.
- W3213017895 hasConceptScore W3213017895C2776789170 @default.
- W3213017895 hasConceptScore W3213017895C2777230291 @default.
- W3213017895 hasConceptScore W3213017895C55493867 @default.
- W3213017895 hasConceptScore W3213017895C556039675 @default.
- W3213017895 hasConceptScore W3213017895C71924100 @default.
- W3213017895 hasFunder F4320313223 @default.
- W3213017895 hasIssue "18" @default.
- W3213017895 hasLocation W32130178951 @default.
- W3213017895 hasLocation W32130178952 @default.
- W3213017895 hasOpenAccess W3213017895 @default.
- W3213017895 hasPrimaryLocation W32130178951 @default.
- W3213017895 hasRelatedWork W1998501735 @default.
- W3213017895 hasRelatedWork W2021109709 @default.
- W3213017895 hasRelatedWork W2165931391 @default.
- W3213017895 hasRelatedWork W2236434600 @default.
- W3213017895 hasRelatedWork W2317950032 @default.
- W3213017895 hasRelatedWork W2554611263 @default.
- W3213017895 hasRelatedWork W2754962382 @default.
- W3213017895 hasRelatedWork W2991875780 @default.
- W3213017895 hasRelatedWork W3156921146 @default.
- W3213017895 hasRelatedWork W2185682558 @default.
- W3213017895 hasVolume "36" @default.
- W3213017895 isParatext "false" @default.
- W3213017895 isRetracted "false" @default.
- W3213017895 magId "3213017895" @default.
- W3213017895 workType "article" @default.