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• W3213041024 abstract "Astragali Radix (AR) is widely used because of its dual use in medicine and food. Wild Astragali Radix from Hunyuan county of Shanxi province in China is accepted as a geo-authentic medicine with high quality and good medicinal effects. Multi-elements of Astragali Radix partially reflect its efficacy and safety. However, there has been no systemic research about the elemental analysis of geo-authentic Astragali Radix until now.In this paper, multi-elemental profiling of Astragali Radix from Gansu, Jilin, Inner Mongolia, Shaanxi and Shanxi provinces in China was carried out.A microwave digestion coupled with inductively coupled plasma-MS (ICP-MS), principal component analysis (PCA), and partial-least square-discriminate analysis (PLS-DA) were used for analysis of the unique elemental accumulation ability of Shanxi wild AR.Compared to the samples from Gansu, Jilin, Inner Mongolia, Shaanxi provinces, and the cultivated samples from Shanxi, for 53 stably detected elements, the concentrations of most elements (Ba, Cs, Ga, La, Pr, and so on) were significantly higher while a few (Cd, Cu, P, W and Zn) were significantly lower in wild Astragali Radix from Shanxi. After binary logistic regression, combinational variable Ba-P was found to be a good marker to distinguish wild Astragali Radix of Shanxi province from the samples with other origins, and the total positive prediction probability of the test samples, both bought from the market and gathered from their original field, could reach 93.8% through external validation using the model.Multi-elemental analysis coupled with PCA, PLS-DA, nonparametric analysis and binary logistic regression can be a good tool for the identification of wild Astragali Radix from Shanxi province.An ICP-MS method was developed and validated for multi-elements. Fifty-three elements in Astragali Radix from samples with different origins were compared. The wild Astragali Radix from Shanxi had unique elemental characteristics. Combinational variable Ba-P is a good marker to identify wild AR from Shanxi." @default.
• W3213041024 created "2021-11-22" @default.
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• W3213041024 date "2021-11-08" @default.
• W3213041024 modified "2023-09-27" @default.
• W3213041024 title "Study of the Unique Characteristics of Multi-Elements of the Wild Astragali Radix from Shanxi Province by Inductively Coupled Plasma Mass Spectrometry" @default.
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• W3213041024 doi "https://doi.org/10.1093/jaoacint/qsab144" @default.
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