Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213151907> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3213151907 endingPage "121283" @default.
- W3213151907 startingPage "121283" @default.
- W3213151907 abstract "In current studies, the disintegration process of tablets has been studied by thermal imaging. The study covers two major aspects; first, new revelations in the mechanism of tablet disintegration, and second, the development of disintegration test as a multi-point test by new thermometric and non-thermometric methods. The study has been carried out on fexofenadine rapidly disintegrating tablets (FEX RDTs) in a dark room cabinet fitted with a Fluke thermal imager and using water as the disintegration medium. The studies exhibit the existence of endothermic peaks during the early penetration of water in FEX RDTs. These endotherms are prominent at the starting point when the disintegration has just started, or the tablet has been just exposed to the water. Such endotherms have not been reported earlier for tablets and can be considered as a part of the wicking mechanism during disintegration. In later stages, when the water has completely wet the tablet, the endotherms are superimposed by exotherms. The endotherms or exotherms have also been used as a measurement of disintegration in the form of a new thermometric parameter, area under temperature curve (AUTC). Non-thermometric disintegration profiling by residual and subtraction methods is also performed. Among these, disintegration by the residual method, i.e., disintegration (residual) is newly introduced. In the end, the principal component analysis (PCA) describes the relationship between various disintegration methods, particle size distribution, and dissolution. PCA reveals that AUTC is the best method for studying the disintegration behavior of FEX RDTs." @default.
- W3213151907 created "2021-11-22" @default.
- W3213151907 creator A5015588693 @default.
- W3213151907 creator A5061663473 @default.
- W3213151907 creator A5076171131 @default.
- W3213151907 creator A5082285311 @default.
- W3213151907 date "2022-01-01" @default.
- W3213151907 modified "2023-09-26" @default.
- W3213151907 title "New insights into the disintegration mechanism and disintegration profiling of rapidly disintegrating tablets (RDTs) by thermal imaging" @default.
- W3213151907 cites W1797382814 @default.
- W3213151907 cites W1869285760 @default.
- W3213151907 cites W1982779297 @default.
- W3213151907 cites W1984963931 @default.
- W3213151907 cites W1991182558 @default.
- W3213151907 cites W1996947306 @default.
- W3213151907 cites W2003886430 @default.
- W3213151907 cites W2006666143 @default.
- W3213151907 cites W2023152055 @default.
- W3213151907 cites W2028015729 @default.
- W3213151907 cites W2044572427 @default.
- W3213151907 cites W2049925761 @default.
- W3213151907 cites W2065709478 @default.
- W3213151907 cites W2110557656 @default.
- W3213151907 cites W2122000898 @default.
- W3213151907 cites W2125067283 @default.
- W3213151907 cites W2126304346 @default.
- W3213151907 cites W2129474261 @default.
- W3213151907 cites W2157902668 @default.
- W3213151907 cites W2167846952 @default.
- W3213151907 cites W2218320402 @default.
- W3213151907 cites W2269860517 @default.
- W3213151907 cites W2507551820 @default.
- W3213151907 cites W2592176131 @default.
- W3213151907 cites W2611940725 @default.
- W3213151907 cites W2625394790 @default.
- W3213151907 cites W2799702325 @default.
- W3213151907 cites W2889188593 @default.
- W3213151907 cites W3021974825 @default.
- W3213151907 doi "https://doi.org/10.1016/j.ijpharm.2021.121283" @default.
- W3213151907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34775042" @default.
- W3213151907 hasPublicationYear "2022" @default.
- W3213151907 type Work @default.
- W3213151907 sameAs 3213151907 @default.
- W3213151907 citedByCount "4" @default.
- W3213151907 countsByYear W32131519072022 @default.
- W3213151907 countsByYear W32131519072023 @default.
- W3213151907 crossrefType "journal-article" @default.
- W3213151907 hasAuthorship W3213151907A5015588693 @default.
- W3213151907 hasAuthorship W3213151907A5061663473 @default.
- W3213151907 hasAuthorship W3213151907A5076171131 @default.
- W3213151907 hasAuthorship W3213151907A5082285311 @default.
- W3213151907 hasConcept C119292831 @default.
- W3213151907 hasConcept C121332964 @default.
- W3213151907 hasConcept C147789679 @default.
- W3213151907 hasConcept C178790620 @default.
- W3213151907 hasConcept C185592680 @default.
- W3213151907 hasConcept C192562407 @default.
- W3213151907 hasConcept C199289684 @default.
- W3213151907 hasConcept C2776124570 @default.
- W3213151907 hasConcept C39519442 @default.
- W3213151907 hasConcept C88380143 @default.
- W3213151907 hasConcept C97355855 @default.
- W3213151907 hasConceptScore W3213151907C119292831 @default.
- W3213151907 hasConceptScore W3213151907C121332964 @default.
- W3213151907 hasConceptScore W3213151907C147789679 @default.
- W3213151907 hasConceptScore W3213151907C178790620 @default.
- W3213151907 hasConceptScore W3213151907C185592680 @default.
- W3213151907 hasConceptScore W3213151907C192562407 @default.
- W3213151907 hasConceptScore W3213151907C199289684 @default.
- W3213151907 hasConceptScore W3213151907C2776124570 @default.
- W3213151907 hasConceptScore W3213151907C39519442 @default.
- W3213151907 hasConceptScore W3213151907C88380143 @default.
- W3213151907 hasConceptScore W3213151907C97355855 @default.
- W3213151907 hasLocation W32131519071 @default.
- W3213151907 hasLocation W32131519072 @default.
- W3213151907 hasOpenAccess W3213151907 @default.
- W3213151907 hasPrimaryLocation W32131519071 @default.
- W3213151907 hasRelatedWork W1524106559 @default.
- W3213151907 hasRelatedWork W1983780679 @default.
- W3213151907 hasRelatedWork W1984907921 @default.
- W3213151907 hasRelatedWork W2045020781 @default.
- W3213151907 hasRelatedWork W2054045083 @default.
- W3213151907 hasRelatedWork W2055282179 @default.
- W3213151907 hasRelatedWork W2567992649 @default.
- W3213151907 hasRelatedWork W2802584363 @default.
- W3213151907 hasRelatedWork W2895345201 @default.
- W3213151907 hasRelatedWork W2899084033 @default.
- W3213151907 hasVolume "611" @default.
- W3213151907 isParatext "false" @default.
- W3213151907 isRetracted "false" @default.
- W3213151907 magId "3213151907" @default.
- W3213151907 workType "article" @default.