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- W3213202389 abstract "Most phages infect free-living bacteria but a few have been identified that infect heritable symbionts of insects or other eukaryotes. Heritable symbionts are usually specialized and isolated from other bacteria with little known about the origins of associated phages. Hamiltonella defensa is a heritable bacterial symbiont of aphids that is usually infected by a tailed, double-stranded DNA phage named APSE.We conducted comparative genomic and phylogenetic studies to determine how APSE is related to other phages and prophages.Each APSE genome was organized into four modules and two predicted functional units. Gene content and order were near-fully conserved in modules 1 and 2, which encode predicted DNA metabolism genes, and module 4, which encodes predicted virion assembly genes. Gene content of module 3, which contains predicted toxin, holin and lysozyme genes differed among haplotypes. Comparisons to other sequenced phages suggested APSE genomes are mosaics with modules 1 and 2 sharing similarities with Bordetella-Bcep-Xylostella fastidiosa-like podoviruses, module 4 sharing similarities with P22-like podoviruses, and module 3 sharing no similarities with known phages. Comparisons to other sequenced bacterial genomes identified APSE-like elements in other heritable insect symbionts (Arsenophonus spp.) and enteric bacteria in the family Morganellaceae.APSEs are most closely related to phage elements in the genus Arsenophonus and other bacteria in the Morganellaceae." @default.
- W3213202389 created "2021-11-22" @default.
- W3213202389 creator A5032598304 @default.
- W3213202389 creator A5033804998 @default.
- W3213202389 creator A5050516508 @default.
- W3213202389 creator A5080274937 @default.
- W3213202389 creator A5084556343 @default.
- W3213202389 date "2021-11-10" @default.
- W3213202389 modified "2023-09-30" @default.
- W3213202389 title "Evolutionary genomics of APSE: a tailed phage that lysogenically converts the bacterium Hamiltonella defensa into a heritable protective symbiont of aphids" @default.
- W3213202389 cites W1552724685 @default.
- W3213202389 cites W1833242130 @default.
- W3213202389 cites W1923633214 @default.
- W3213202389 cites W1948137225 @default.
- W3213202389 cites W1964517680 @default.
- W3213202389 cites W1969372407 @default.
- W3213202389 cites W1971178500 @default.
- W3213202389 cites W1976404084 @default.
- W3213202389 cites W1978069388 @default.
- W3213202389 cites W1978339035 @default.
- W3213202389 cites W1979655623 @default.
- W3213202389 cites W1986068618 @default.
- W3213202389 cites W1990515956 @default.
- W3213202389 cites W1992141349 @default.
- W3213202389 cites W1992783218 @default.
- W3213202389 cites W1995701890 @default.
- W3213202389 cites W1996864133 @default.
- W3213202389 cites W1996897262 @default.
- W3213202389 cites W2004418732 @default.
- W3213202389 cites W2004589024 @default.
- W3213202389 cites W2012897015 @default.
- W3213202389 cites W2013922167 @default.
- W3213202389 cites W201727952 @default.
- W3213202389 cites W2019833246 @default.
- W3213202389 cites W2026811552 @default.
- W3213202389 cites W2035677469 @default.
- W3213202389 cites W2037597719 @default.
- W3213202389 cites W2040323948 @default.
- W3213202389 cites W2041472479 @default.
- W3213202389 cites W2043522409 @default.
- W3213202389 cites W2044479234 @default.
- W3213202389 cites W2046861479 @default.
- W3213202389 cites W2049331273 @default.
- W3213202389 cites W2049787303 @default.
- W3213202389 cites W2050783903 @default.
- W3213202389 cites W2055043387 @default.
- W3213202389 cites W2055298722 @default.
- W3213202389 cites W2056380742 @default.
- W3213202389 cites W2060834037 @default.
- W3213202389 cites W2068613608 @default.
- W3213202389 cites W2069514794 @default.
- W3213202389 cites W2073037954 @default.
- W3213202389 cites W2074318148 @default.
- W3213202389 cites W2074578367 @default.
- W3213202389 cites W2075519966 @default.
- W3213202389 cites W2077432496 @default.
- W3213202389 cites W2078689375 @default.
- W3213202389 cites W2084192230 @default.
- W3213202389 cites W2085730012 @default.
- W3213202389 cites W2088522355 @default.
- W3213202389 cites W2090636516 @default.
- W3213202389 cites W2091030812 @default.
- W3213202389 cites W2091585799 @default.
- W3213202389 cites W2095724630 @default.
- W3213202389 cites W2099490952 @default.
- W3213202389 cites W2100152398 @default.
- W3213202389 cites W2104341696 @default.
- W3213202389 cites W2107954245 @default.
- W3213202389 cites W2108375187 @default.
- W3213202389 cites W2109721710 @default.
- W3213202389 cites W2111441915 @default.
- W3213202389 cites W2114853012 @default.
- W3213202389 cites W2123197495 @default.
- W3213202389 cites W2128880918 @default.
- W3213202389 cites W2129721986 @default.
- W3213202389 cites W2129733288 @default.
- W3213202389 cites W2130354150 @default.
- W3213202389 cites W2130747214 @default.
- W3213202389 cites W2135732088 @default.
- W3213202389 cites W2138093179 @default.
- W3213202389 cites W2141052558 @default.
- W3213202389 cites W2150570211 @default.
- W3213202389 cites W2154421188 @default.
- W3213202389 cites W2154793163 @default.
- W3213202389 cites W2156575704 @default.
- W3213202389 cites W2160378127 @default.
- W3213202389 cites W2162468551 @default.
- W3213202389 cites W2169641336 @default.
- W3213202389 cites W2170551349 @default.
- W3213202389 cites W2170661260 @default.
- W3213202389 cites W2173979572 @default.
- W3213202389 cites W2222488794 @default.
- W3213202389 cites W2345952626 @default.
- W3213202389 cites W2461450346 @default.
- W3213202389 cites W2555394080 @default.
- W3213202389 cites W2561455358 @default.
- W3213202389 cites W2563535234 @default.
- W3213202389 cites W2575283327 @default.
- W3213202389 cites W2580191062 @default.
- W3213202389 cites W2596857118 @default.