FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213232008> ?p ?o ?g. }

• W3213232008 abstract "While the etiology of hippocampal sclerosis (HS) in epilepsy patients remains unknown, distinct phenotypes of hippocampal subfield atrophy have been associated with different clinical presentations and surgical outcomes. The advent of novel techniques including ultra-high field 7T magnetic resonance imaging (MRI) and automated subfield volumetry have further enabled detection of hippocampal pathology in patients with epilepsy, however, studies combining both 7T MRI and automated segmentation in epilepsy patients with normal-appearing clinical MRI are limited. In this study, we present a novel application of the automated segmentation of hippocampal subfields (ASHS) software to determine subfield volumes of the CA1, CA2/3, CA4/DG, and the subiculum using ultra high-field 7T MRI scans, including T1-weighted MP2RAGE and T2-TSE sequences, in 27 patients with either mesial temporal lobe epilepsy (mTLE) or neocortical epilepsy (NE) compared to age and gender matched healthy controls. We found that 7T improved visualization of structural abnormalities not otherwise seen on clinical strength MRIs in patients with unilateral mTLE. Additionally, our automated segmentation algorithm was able to detect structural differences in volume and asymmetry across hippocampal subfields in unilateral mTLE patients compared to controls. Specifically, amongst unilateral mTLE patients with longer disease durations, volume loss was observed in the ipsilateral CA1 and CA2/3 subfields and contralateral CA1. There were no differences in subfield volumes in patients with NE compared to controls. We report the first application of 7T with automated segmentation to characterize the relationship between disease duration burden and asymmetry across specific hippocampal subfields in this population. Disease duration was found to have a statistically significant positive relationship with subfield asymmetry within the unilateral mTLE cohort. These findings highlight the ability of 7T MRI and automated segmentation to provide novel qualitative and quantitative information in epilepsy patients who are otherwise MRI-negative at clinical field strengths." @default.
• W3213232008 created "2021-11-22" @default.
• W3213232008 creator A5000818895 @default.
• W3213232008 creator A5002706376 @default.
• W3213232008 creator A5032134108 @default.
• W3213232008 creator A5036456024 @default.
• W3213232008 creator A5039529516 @default.
• W3213232008 creator A5043723831 @default.
• W3213232008 creator A5066252075 @default.
• W3213232008 creator A5073037534 @default.
• W3213232008 creator A5082877649 @default.
• W3213232008 creator A5090682916 @default.
• W3213232008 date "2021-11-15" @default.
• W3213232008 modified "2023-09-23" @default.
• W3213232008 title "Detection of Hippocampal Subfield Asymmetry at 7T With Automated Segmentation in Epilepsy Patients With Normal Clinical Strength MRIs" @default.
• W3213232008 cites W1464310731 @default.
• W3213232008 cites W1552531538 @default.
• W3213232008 cites W1739514309 @default.
• W3213232008 cites W1898603201 @default.
• W3213232008 cites W1968151197 @default.
• W3213232008 cites W1972696506 @default.
• W3213232008 cites W1974809694 @default.
• W3213232008 cites W1976992387 @default.
• W3213232008 cites W1998526664 @default.
• W3213232008 cites W2001944414 @default.
• W3213232008 cites W2007683591 @default.
• W3213232008 cites W2012150151 @default.
• W3213232008 cites W2015513895 @default.
• W3213232008 cites W2022866082 @default.
• W3213232008 cites W2044857503 @default.
• W3213232008 cites W2051950153 @default.
• W3213232008 cites W2052222853 @default.
• W3213232008 cites W2062383826 @default.
• W3213232008 cites W2089312730 @default.
• W3213232008 cites W2091036726 @default.
• W3213232008 cites W2144227215 @default.
• W3213232008 cites W2160381375 @default.
• W3213232008 cites W2227745747 @default.
• W3213232008 cites W2437128141 @default.
• W3213232008 cites W2516686925 @default.
• W3213232008 cites W2767415790 @default.
• W3213232008 cites W2888483565 @default.
• W3213232008 cites W2913802592 @default.
• W3213232008 cites W2922862354 @default.
• W3213232008 cites W4211013529 @default.
• W3213232008 doi "https://doi.org/10.3389/fneur.2021.682615" @default.
• W3213232008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34867703" @default.
• W3213232008 hasPublicationYear "2021" @default.
• W3213232008 type Work @default.
• W3213232008 sameAs 3213232008 @default.
• W3213232008 citedByCount "2" @default.
• W3213232008 countsByYear W32132320082023 @default.
• W3213232008 crossrefType "journal-article" @default.
• W3213232008 hasAuthorship W3213232008A5000818895 @default.
• W3213232008 hasAuthorship W3213232008A5002706376 @default.
• W3213232008 hasAuthorship W3213232008A5032134108 @default.
• W3213232008 hasAuthorship W3213232008A5036456024 @default.
• W3213232008 hasAuthorship W3213232008A5039529516 @default.
• W3213232008 hasAuthorship W3213232008A5043723831 @default.
• W3213232008 hasAuthorship W3213232008A5066252075 @default.
• W3213232008 hasAuthorship W3213232008A5073037534 @default.
• W3213232008 hasAuthorship W3213232008A5082877649 @default.
• W3213232008 hasAuthorship W3213232008A5090682916 @default.
• W3213232008 hasBestOaLocation W32132320081 @default.
• W3213232008 hasConcept C126322002 @default.
• W3213232008 hasConcept C126838900 @default.
• W3213232008 hasConcept C142724271 @default.
• W3213232008 hasConcept C143409427 @default.
• W3213232008 hasConcept C148762608 @default.
• W3213232008 hasConcept C15744967 @default.
• W3213232008 hasConcept C169760540 @default.
• W3213232008 hasConcept C2776464000 @default.
• W3213232008 hasConcept C2777597344 @default.
• W3213232008 hasConcept C2778186239 @default.
• W3213232008 hasConcept C2778499278 @default.
• W3213232008 hasConcept C2781099131 @default.
• W3213232008 hasConcept C2781172350 @default.
• W3213232008 hasConcept C2908647359 @default.
• W3213232008 hasConcept C71924100 @default.
• W3213232008 hasConcept C99454951 @default.
• W3213232008 hasConceptScore W3213232008C126322002 @default.
• W3213232008 hasConceptScore W3213232008C126838900 @default.
• W3213232008 hasConceptScore W3213232008C142724271 @default.
• W3213232008 hasConceptScore W3213232008C143409427 @default.
• W3213232008 hasConceptScore W3213232008C148762608 @default.
• W3213232008 hasConceptScore W3213232008C15744967 @default.
• W3213232008 hasConceptScore W3213232008C169760540 @default.
• W3213232008 hasConceptScore W3213232008C2776464000 @default.
• W3213232008 hasConceptScore W3213232008C2777597344 @default.
• W3213232008 hasConceptScore W3213232008C2778186239 @default.
• W3213232008 hasConceptScore W3213232008C2778499278 @default.
• W3213232008 hasConceptScore W3213232008C2781099131 @default.
• W3213232008 hasConceptScore W3213232008C2781172350 @default.
• W3213232008 hasConceptScore W3213232008C2908647359 @default.
• W3213232008 hasConceptScore W3213232008C71924100 @default.
• W3213232008 hasConceptScore W3213232008C99454951 @default.
• W3213232008 hasFunder F4320337346 @default.
• W3213232008 hasFunder F4320337359 @default.
• W3213232008 hasLocation W32132320081 @default.
• W3213232008 hasLocation W32132320082 @default.

• next