Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213303650> ?p ?o ?g. }
- W3213303650 endingPage "1310" @default.
- W3213303650 startingPage "1310" @default.
- W3213303650 abstract "Acupuncture at acupoints Baihui (GV20) and Dazhui (GV14) has been shown to promote functional recovery after stroke. However, the contribution of the contralateral primary sensory cortex (S1) to recovery remains unclear. In this study, unilateral local ischemic infarction of the primary motor cortex (M1) was induced by photothrombosis in a mouse model. Electroacupuncture (EA) was subsequently performed at acupoints GV20 and GV14 and neuronal activity and functional connectivity of contralateral S1 and M1 were detected using in vivo and in vitro electrophysiological recording techniques. Our results showed that blood perfusion and neuronal interaction between contralateral M1 and S1 is impaired after unilateral M1 infarction. Intrinsic neuronal excitability and activity were also disturbed, which was rescued by EA. Furthermore, the effectiveness of EA treatment was inhibited after virus-mediated neuronal ablation of the contralateral S1. We conclude that neuronal activity of the contralateral S1 is important for EA-mediated recovery after focal M1 infarction. Our study provides insight into how the S1-M1 circuit might be involved in the mechanism of EA treatment of unilateral cerebral infarction. The animal experiments were approved by the Committee for Care and Use of Research Animals of Guangzhou University of Chinese Medicine (approval No. 20200407009) April 7, 2020." @default.
- W3213303650 created "2021-11-22" @default.
- W3213303650 creator A5000862371 @default.
- W3213303650 creator A5014097455 @default.
- W3213303650 creator A5031459543 @default.
- W3213303650 creator A5034530650 @default.
- W3213303650 creator A5051674026 @default.
- W3213303650 creator A5052251380 @default.
- W3213303650 creator A5078505569 @default.
- W3213303650 creator A5089360021 @default.
- W3213303650 date "2022-01-01" @default.
- W3213303650 modified "2023-10-01" @default.
- W3213303650 title "Contralateral S1 function is involved in electroacupuncture treatment-mediated recovery after focal unilateral M1 infarction" @default.
- W3213303650 cites W1496587751 @default.
- W3213303650 cites W1774728488 @default.
- W3213303650 cites W1895896934 @default.
- W3213303650 cites W1963614821 @default.
- W3213303650 cites W1977100729 @default.
- W3213303650 cites W1988993555 @default.
- W3213303650 cites W1989687497 @default.
- W3213303650 cites W1992415357 @default.
- W3213303650 cites W2007788304 @default.
- W3213303650 cites W2008284899 @default.
- W3213303650 cites W2010967559 @default.
- W3213303650 cites W2016236205 @default.
- W3213303650 cites W2021271087 @default.
- W3213303650 cites W2027045997 @default.
- W3213303650 cites W2027916217 @default.
- W3213303650 cites W2031024798 @default.
- W3213303650 cites W2032773159 @default.
- W3213303650 cites W2045421141 @default.
- W3213303650 cites W2046219703 @default.
- W3213303650 cites W2054423368 @default.
- W3213303650 cites W2056571449 @default.
- W3213303650 cites W2086664483 @default.
- W3213303650 cites W2099512174 @default.
- W3213303650 cites W2106158457 @default.
- W3213303650 cites W2111106809 @default.
- W3213303650 cites W2120628526 @default.
- W3213303650 cites W2125119949 @default.
- W3213303650 cites W2126597767 @default.
- W3213303650 cites W2132878222 @default.
- W3213303650 cites W2145481295 @default.
- W3213303650 cites W2151718948 @default.
- W3213303650 cites W2156315816 @default.
- W3213303650 cites W2164031120 @default.
- W3213303650 cites W2341685500 @default.
- W3213303650 cites W2394624041 @default.
- W3213303650 cites W2414038626 @default.
- W3213303650 cites W2467519109 @default.
- W3213303650 cites W2504058217 @default.
- W3213303650 cites W2517858288 @default.
- W3213303650 cites W2601781076 @default.
- W3213303650 cites W2605567492 @default.
- W3213303650 cites W2696053297 @default.
- W3213303650 cites W2766518246 @default.
- W3213303650 cites W2785332246 @default.
- W3213303650 cites W2800758050 @default.
- W3213303650 cites W2887187234 @default.
- W3213303650 cites W2894224653 @default.
- W3213303650 cites W2896772708 @default.
- W3213303650 cites W2905003219 @default.
- W3213303650 cites W2945870049 @default.
- W3213303650 cites W2951347353 @default.
- W3213303650 cites W2992657753 @default.
- W3213303650 cites W3009731615 @default.
- W3213303650 cites W3011513896 @default.
- W3213303650 cites W3033782703 @default.
- W3213303650 cites W3033897926 @default.
- W3213303650 cites W3037921247 @default.
- W3213303650 cites W3088966414 @default.
- W3213303650 cites W783001870 @default.
- W3213303650 doi "https://doi.org/10.4103/1673-5374.327355" @default.
- W3213303650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34782576" @default.
- W3213303650 hasPublicationYear "2022" @default.
- W3213303650 type Work @default.
- W3213303650 sameAs 3213303650 @default.
- W3213303650 citedByCount "4" @default.
- W3213303650 countsByYear W32133036502022 @default.
- W3213303650 countsByYear W32133036502023 @default.
- W3213303650 crossrefType "journal-article" @default.
- W3213303650 hasAuthorship W3213303650A5000862371 @default.
- W3213303650 hasAuthorship W3213303650A5014097455 @default.
- W3213303650 hasAuthorship W3213303650A5031459543 @default.
- W3213303650 hasAuthorship W3213303650A5034530650 @default.
- W3213303650 hasAuthorship W3213303650A5051674026 @default.
- W3213303650 hasAuthorship W3213303650A5052251380 @default.
- W3213303650 hasAuthorship W3213303650A5078505569 @default.
- W3213303650 hasAuthorship W3213303650A5089360021 @default.
- W3213303650 hasBestOaLocation W32133036501 @default.
- W3213303650 hasConcept C126322002 @default.
- W3213303650 hasConcept C127413603 @default.
- W3213303650 hasConcept C142724271 @default.
- W3213303650 hasConcept C150903083 @default.
- W3213303650 hasConcept C15744967 @default.
- W3213303650 hasConcept C164705383 @default.
- W3213303650 hasConcept C169760540 @default.
- W3213303650 hasConcept C204787440 @default.