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- W3213352007 abstract "Background Port-wine stain (PWS) is a congenital capillary malformation that often occurs on the face. Feasible and quantitative evaluation of facial port-wine stain (FPWS) can significantly impact its clinical management and aid in future research. Aim To develop and validate an easy-to-use scoring system for FPWS evaluation. Methods A facial port-wine stain area and severity index (FSASI) scoring system was proposed. To determine the FSASI score, the face was divided into four regions: forehead, right malar, left malar, and perioral. The severity of FPWS in each region was evaluated by three factors: percentage of the area affected, lesion color, and thickness. To evaluate the intra- and inter-rater reliability of FSASI, two separate FSASI assessments on 111 clinical pictures were conducted by each rater in a one-week interval, and the results from 6 independent raters at different time points were compared. Validity of the FSASI scores was assessed by comparing it with physician global assessment (PGA) and traditional classification data. Validity of the area and color elements of FSASI was also determined. The changes in FSASI scores after vascular-targeted photodynamic therapy (V-PDT) were analyzed to evaluate the treatment effect. Results The FSASI scoring system showed good intra- and inter-rater reliability (ICC >0.75, p < 0.001) and was found to be comparable to PGA scores (Spearman's r = 0.752–0.907, p < 0.001) and traditional classification data (Spearman's r = 0.426–0.662, p < 0.001). Efficacy analysis indicated that FSASI scores decreased after V-PDT treatment. Conclusion The results of this study demonstrated the reliability and validity of FSASI, which may be applied to assess the severity of FPWS and to evaluate treatment effects in clinical practice and research." @default.
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- W3213352007 date "2021-11-06" @default.
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- W3213352007 title "A proposed scoring system for facial port‐wine stain evaluation: Facial port‐wine stain area and severity index" @default.
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- W3213352007 doi "https://doi.org/10.1111/jocd.14574" @default.
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