Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213366643> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W3213366643 endingPage "06" @default.
- W3213366643 startingPage "01" @default.
- W3213366643 abstract "Zinc (Ⅱ)-immune pediatric virucidal activities for children with 2019-nCoV prevention and COVID-19 bronchitis and pneumonia are discussed, and these Zn2+-immune pediatric virucidal effects result in the following. Zinc intakes by zinc induced immunity are required 3 mg/day for 7 month to 3 years, 5 mg/day for 4~ 8 years, and 8 mg/day for 9 ~13 years in children. Zinc supplementation have been assessed, from 15 mg to 140 mg/week, with the upper range exceeding the recommended daily infection (RDI) for children of 2 mg/day for children less than one year of age and up to 7 mg/day for children between 1 to 3 years. Zinc induced pediatric preventing respiratory 2019-nCoV is required that supplementation with zinc gluconate 20 mg in Zn deficient children resulted in a nearly twofold reduction of acute lower respiratory infections as well as the time to recovery. Zinc supplementation in children is associated with a reduction in the incidence and prevalence of pneumonia. Preventing 2019-nCoV pneumonia is required that zinc supplementation alone (10 to 20 mg) for more than 3 months significantly reduces in the rate of pneumonia. Prophylactic zinc supplementation for two weeks may reduce the morbidity due to acute lower respiratory infections. Zinc gluconate supplement may result in significant reduction in respiratory morbidity among children with acute lower respiratory infections. In addition. as serum zinc level of Acute Respiratory Infection (ARI)-children was very low, higher zinc concentration treatments as low sociodemographic factors, poor nutritional status and male children were prevalently associated with higher incidence of acute respiratory infections. Adjuvant treatment with 20 mg zinc/day accelerates recovery from severe pneumonia in children. Primary outcome was recovery from pneumonia and 30 mg/day of zinc supplementation reduces pneumonia in children with chronic kidney disease (CKD). Zinc supplementation + Chloroquine (CQ)/hydroxychloroquine (HCQ) may be more effective in reducing COVID-19 morbidity and mortality than CQ or HCQ in monotherapy. The serum zinc level returned to a normal level (median, 53.20 μmol/L) on day 12±2 in the treatment. There was no statistical difference in the pediatric critic illness score, lung injury score, length of hospital stay, and duration of mechanical ventilation between the zinc treatments. The oxidative stress in pediatric diseases causes an oxidative burst that results in a respiratory burst and rapid ROS production. Thus, zinc pediatric intake may be required to be effective range 10~20 mg/d for 2019-CoV prevention, 10~30 mg/d for reduction of COVID-19 bronchitis, and 20~30 mg/d for recovery from COVID-19 pneumonia, in which Zn2+ could bind with viral surface proteins by Zn2+ions-centered tetrahedrally coordination pattern." @default.
- W3213366643 created "2021-11-22" @default.
- W3213366643 creator A5016398059 @default.
- W3213366643 date "2020-09-04" @default.
- W3213366643 modified "2023-09-26" @default.
- W3213366643 title "Zinc (?)-immune pediatric virucidal activities for 2019-nCoV prevention and therapeutic effects of COVID-19 bronchitis and pneumonia" @default.
- W3213366643 doi "https://doi.org/10.31579/2692-9406/012" @default.
- W3213366643 hasPublicationYear "2020" @default.
- W3213366643 type Work @default.
- W3213366643 sameAs 3213366643 @default.
- W3213366643 citedByCount "0" @default.
- W3213366643 crossrefType "journal-article" @default.
- W3213366643 hasAuthorship W3213366643A5016398059 @default.
- W3213366643 hasBestOaLocation W32133666431 @default.
- W3213366643 hasConcept C120665830 @default.
- W3213366643 hasConcept C121332964 @default.
- W3213366643 hasConcept C126322002 @default.
- W3213366643 hasConcept C178790620 @default.
- W3213366643 hasConcept C185592680 @default.
- W3213366643 hasConcept C203014093 @default.
- W3213366643 hasConcept C2777914695 @default.
- W3213366643 hasConcept C2779993553 @default.
- W3213366643 hasConcept C534529494 @default.
- W3213366643 hasConcept C535196362 @default.
- W3213366643 hasConcept C61511704 @default.
- W3213366643 hasConcept C71924100 @default.
- W3213366643 hasConcept C8891405 @default.
- W3213366643 hasConcept C90924648 @default.
- W3213366643 hasConceptScore W3213366643C120665830 @default.
- W3213366643 hasConceptScore W3213366643C121332964 @default.
- W3213366643 hasConceptScore W3213366643C126322002 @default.
- W3213366643 hasConceptScore W3213366643C178790620 @default.
- W3213366643 hasConceptScore W3213366643C185592680 @default.
- W3213366643 hasConceptScore W3213366643C203014093 @default.
- W3213366643 hasConceptScore W3213366643C2777914695 @default.
- W3213366643 hasConceptScore W3213366643C2779993553 @default.
- W3213366643 hasConceptScore W3213366643C534529494 @default.
- W3213366643 hasConceptScore W3213366643C535196362 @default.
- W3213366643 hasConceptScore W3213366643C61511704 @default.
- W3213366643 hasConceptScore W3213366643C71924100 @default.
- W3213366643 hasConceptScore W3213366643C8891405 @default.
- W3213366643 hasConceptScore W3213366643C90924648 @default.
- W3213366643 hasIssue "2" @default.
- W3213366643 hasLocation W32133666431 @default.
- W3213366643 hasOpenAccess W3213366643 @default.
- W3213366643 hasPrimaryLocation W32133666431 @default.
- W3213366643 hasRelatedWork W1580426574 @default.
- W3213366643 hasRelatedWork W2089620537 @default.
- W3213366643 hasRelatedWork W2116740923 @default.
- W3213366643 hasRelatedWork W2275480158 @default.
- W3213366643 hasRelatedWork W2371214482 @default.
- W3213366643 hasRelatedWork W2398656954 @default.
- W3213366643 hasRelatedWork W2413281042 @default.
- W3213366643 hasRelatedWork W2417363182 @default.
- W3213366643 hasRelatedWork W4238089809 @default.
- W3213366643 hasRelatedWork W4324309789 @default.
- W3213366643 hasVolume "1" @default.
- W3213366643 isParatext "false" @default.
- W3213366643 isRetracted "false" @default.
- W3213366643 magId "3213366643" @default.
- W3213366643 workType "article" @default.