Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213370512> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3213370512 abstract "Emergency medical services (EMS) patients with acute dyspnea require prompt treatment. Limited data describe out-of-hospital dyspnea treatment with non-invasive, positive-pressure ventilation (NIPPV), including continuous positive airway pressure (CPAP) or bi-level positive air pressure (BPAP). We sought to determine the course and outcomes of out-of-hospital acute dyspnea patients treated with NIPPV.We analyzed retrospective data on 1289 EMS agencies from the ESO Data Collaborative (ESO, Inc., Austin, TX) between January and December 2018. We defined acute dyspnea as adults with an initial respiratory rate ≥ 30 breaths/min (bpm), with a primary or secondary EMS subjective impression of a respiratory condition, who received oxygen and/or a respiratory medication and had 2 or more recordings of respiratory rate (RR). We excluded patients with trauma and those with altered mental status. We identified cases receiving care with and without NIPPV. The primary outcome was change in respiratory rate (RR), censored at 90 minutes of treatment. We compared baseline characteristics between NIPPV and non-NIPPV patients. We compared RR changes between NIPPV and non-NIPPV patients at 20 and 40 minutes of treatment. Using mixed linear, fractional polynomial, and multiple spline models, we examined the association of out-of-hospital NIPPV with overall change in RR. Secondary outcomes included whether the patient received advanced airway treatment (intubation, supraglottic airway device, and/or cricothyroidotomy).We analyzed 33,585 EMS encounters for patients with acute dyspnea, including 8,750 (26.1%) NIPPV and 24,835 (73.9%) non-NIPPV encounters. Median treatment duration was similar between NIPPV and non-NIPPV (23.3 minutes vs 23.6 minutes, rank-sum P = 0.266). Common concurrent treatments included albuterol (NIPPV, 48.8%; non-NIPPV, 46.2%), ipratropium bromide (27.9%, 24.8%), and methylprednisolone (24.9%, 18.5%). At 20 minutes, mean RR change was slightly lower for the NIPPV group than non-NIPPV; -6.0 versus -6.8 breaths/min. At 40 minutes, mean RR change was similar between NIPPV and non-NIPPV groups; -7.7 versus -7.9 breaths/min. On linear mixed modeling adjusted for age, sex, incident location, race, ethnicity, agency type, initial RR, and medication use, NIPPV was associated with a smaller RR decrease across time than NIPPV; [NIPPV × time] interaction P < 0.001. Out-of-hospital advanced airway placement (endotracheal intubation or supraglottic airway insertion) was higher for NIPPV than non-NIPPV group (2.3% vs 1.3%, odds ratio = 2.23, 95% confidence interval = 2.01-2.47).NIPPV has been proven to be an effective treatment for out-of-hospital patients experiencing acute dyspnea through prior studies. Our findings provide detailed insight into characteristics and use of NIPPV and highlight the commonality of this treatment modality with use in over 1 in 4 patients in respiratory distress." @default.
- W3213370512 created "2021-11-22" @default.
- W3213370512 creator A5008212320 @default.
- W3213370512 creator A5017301837 @default.
- W3213370512 creator A5027386000 @default.
- W3213370512 creator A5027935411 @default.
- W3213370512 creator A5072244544 @default.
- W3213370512 creator A5073527721 @default.
- W3213370512 date "2021-11-04" @default.
- W3213370512 modified "2023-10-10" @default.
- W3213370512 title "Out‐of‐hospital, non‐invasive, positive‐pressure ventilation for acute dyspnea" @default.
- W3213370512 cites W1966887017 @default.
- W3213370512 cites W2078280157 @default.
- W3213370512 cites W2099872392 @default.
- W3213370512 cites W2145617074 @default.
- W3213370512 cites W2344783184 @default.
- W3213370512 cites W2407300608 @default.
- W3213370512 cites W3000096259 @default.
- W3213370512 cites W3042529073 @default.
- W3213370512 doi "https://doi.org/10.1002/emp2.12542" @default.
- W3213370512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8567746" @default.
- W3213370512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34761248" @default.
- W3213370512 hasPublicationYear "2021" @default.
- W3213370512 type Work @default.
- W3213370512 sameAs 3213370512 @default.
- W3213370512 citedByCount "2" @default.
- W3213370512 countsByYear W32133705122022 @default.
- W3213370512 crossrefType "journal-article" @default.
- W3213370512 hasAuthorship W3213370512A5008212320 @default.
- W3213370512 hasAuthorship W3213370512A5017301837 @default.
- W3213370512 hasAuthorship W3213370512A5027386000 @default.
- W3213370512 hasAuthorship W3213370512A5027935411 @default.
- W3213370512 hasAuthorship W3213370512A5072244544 @default.
- W3213370512 hasAuthorship W3213370512A5073527721 @default.
- W3213370512 hasBestOaLocation W32133705123 @default.
- W3213370512 hasConcept C105922876 @default.
- W3213370512 hasConcept C194828623 @default.
- W3213370512 hasConcept C2775867611 @default.
- W3213370512 hasConcept C2776006263 @default.
- W3213370512 hasConcept C2776888751 @default.
- W3213370512 hasConcept C2778716859 @default.
- W3213370512 hasConcept C2779547634 @default.
- W3213370512 hasConcept C2992376330 @default.
- W3213370512 hasConcept C42219234 @default.
- W3213370512 hasConcept C71924100 @default.
- W3213370512 hasConceptScore W3213370512C105922876 @default.
- W3213370512 hasConceptScore W3213370512C194828623 @default.
- W3213370512 hasConceptScore W3213370512C2775867611 @default.
- W3213370512 hasConceptScore W3213370512C2776006263 @default.
- W3213370512 hasConceptScore W3213370512C2776888751 @default.
- W3213370512 hasConceptScore W3213370512C2778716859 @default.
- W3213370512 hasConceptScore W3213370512C2779547634 @default.
- W3213370512 hasConceptScore W3213370512C2992376330 @default.
- W3213370512 hasConceptScore W3213370512C42219234 @default.
- W3213370512 hasConceptScore W3213370512C71924100 @default.
- W3213370512 hasIssue "6" @default.
- W3213370512 hasLocation W32133705121 @default.
- W3213370512 hasLocation W32133705122 @default.
- W3213370512 hasLocation W32133705123 @default.
- W3213370512 hasLocation W32133705124 @default.
- W3213370512 hasLocation W32133705125 @default.
- W3213370512 hasOpenAccess W3213370512 @default.
- W3213370512 hasPrimaryLocation W32133705121 @default.
- W3213370512 hasRelatedWork W1967491365 @default.
- W3213370512 hasRelatedWork W1980062584 @default.
- W3213370512 hasRelatedWork W1986167255 @default.
- W3213370512 hasRelatedWork W2332379536 @default.
- W3213370512 hasRelatedWork W2348727334 @default.
- W3213370512 hasRelatedWork W2357143860 @default.
- W3213370512 hasRelatedWork W3028787224 @default.
- W3213370512 hasRelatedWork W3117439638 @default.
- W3213370512 hasRelatedWork W3176304498 @default.
- W3213370512 hasRelatedWork W4386231388 @default.
- W3213370512 hasVolume "2" @default.
- W3213370512 isParatext "false" @default.
- W3213370512 isRetracted "false" @default.
- W3213370512 magId "3213370512" @default.
- W3213370512 workType "article" @default.