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• W3213570395 abstract "A wealth of research is dedicated to understanding how resistance against parasites is conferred and how parasite-driven pathology is regulated. This research is in part driven by the hope to better treatments for parasitic diseases of humans and livestock, and in part by immunologists who use parasitic infections as biomedical tools to evoke physiological immune responses. Much of the current mechanistic knowledge has been discovered in laboratory studies using model organisms, especially the laboratory mouse. However, wildlife are also hosts to a range of parasites. Through the study of host-parasite interactions in these non-laboratory systems we can gain a deeper understanding of parasite immunology in a more natural, complex environment. With a focus on helminth parasites, we here explore the insights gained into parasite-induced immune responses through (for immunologists) non-conventional experimental systems, and how current core findings from laboratory studies are reflected in these more natural conditions. The quality of the immune response is undoubtedly a central player in susceptibility versus resistance, as many laboratory studies have shown. Yet, in the wild, parasite infections tend to be chronic diseases. Whilst reading our review, we encourage the reader to consider the following questions which may (only) be answered by studying naturally occurring parasites in the wild: a) what type of immune responses are mounted against parasites in different hosts in the wild, and how do they vary within an individual over time, between individuals of the same species and between species? b) can we use wild or semi-wild study systems to understand the evolutionary drivers for tolerance versus resistance towards a parasite? c) what determines the ability of the host to cope with an infection and is there a link with the type of immune response mounted? d) can we modulate environmental factors to manipulate a wild animal's immune response to parasitic infections, with translation potential for humans, wildlife, and livestock? and e) in context of this special issue, what lessons for Type 2 immunity can we glean from studying animals in their natural environments? Further, we aim to integrate some of the knowledge gained in semi-wild and wild settings with knowledge gained from traditional laboratory-based research, and to raise awareness for the opportunities (and challenges) that come with integrating a multitude of naturally-occurring variables into immunoparasitological research." @default.
• W3213570395 created "2021-11-22" @default.
• W3213570395 creator A5001122976 @default.
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• W3213570395 date "2021-03-01" @default.
• W3213570395 modified "2023-10-03" @default.
• W3213570395 title "Embracing nature’s complexity: Immunoparasitology in the wild" @default.
• W3213570395 cites W102561129 @default.
• W3213570395 cites W1552673739 @default.
• W3213570395 cites W1581349283 @default.
• W3213570395 cites W1805101691 @default.
• W3213570395 cites W1910954834 @default.
• W3213570395 cites W1911175303 @default.
• W3213570395 cites W1960800379 @default.
• W3213570395 cites W1968254266 @default.
• W3213570395 cites W1969554943 @default.
• W3213570395 cites W1969843422 @default.
• W3213570395 cites W1970497524 @default.
• W3213570395 cites W1972922050 @default.
• W3213570395 cites W1973408564 @default.
• W3213570395 cites W1974805591 @default.
• W3213570395 cites W1980694247 @default.
• W3213570395 cites W1983255128 @default.
• W3213570395 cites W1987604598 @default.
• W3213570395 cites W1991688936 @default.
• W3213570395 cites W1996905075 @default.
• W3213570395 cites W1999046139 @default.
• W3213570395 cites W2002682820 @default.
• W3213570395 cites W2005379242 @default.
• W3213570395 cites W2019870550 @default.
• W3213570395 cites W2024995104 @default.
• W3213570395 cites W2025891236 @default.
• W3213570395 cites W2026182023 @default.
• W3213570395 cites W2026574632 @default.
• W3213570395 cites W2026691681 @default.
• W3213570395 cites W2027154900 @default.
• W3213570395 cites W2029286150 @default.
• W3213570395 cites W2030714357 @default.
• W3213570395 cites W2032199586 @default.
• W3213570395 cites W2037309013 @default.
• W3213570395 cites W2042738268 @default.
• W3213570395 cites W2043424477 @default.
• W3213570395 cites W2052466505 @default.
• W3213570395 cites W2067049479 @default.
• W3213570395 cites W2069802425 @default.
• W3213570395 cites W2071509106 @default.
• W3213570395 cites W2077865652 @default.
• W3213570395 cites W2083231575 @default.
• W3213570395 cites W2089086808 @default.
• W3213570395 cites W2094495174 @default.
• W3213570395 cites W2096387106 @default.
• W3213570395 cites W2096478498 @default.
• W3213570395 cites W2100534111 @default.
• W3213570395 cites W2102499150 @default.
• W3213570395 cites W2103442971 @default.
• W3213570395 cites W2104941073 @default.
• W3213570395 cites W2107949025 @default.
• W3213570395 cites W2111593745 @default.
• W3213570395 cites W2111982541 @default.
• W3213570395 cites W2113041180 @default.
• W3213570395 cites W2115199664 @default.
• W3213570395 cites W2115694713 @default.
• W3213570395 cites W2122517838 @default.
• W3213570395 cites W2123939899 @default.
• W3213570395 cites W2125078295 @default.
• W3213570395 cites W2126512026 @default.
• W3213570395 cites W2128427264 @default.
• W3213570395 cites W2135166271 @default.
• W3213570395 cites W2138076785 @default.
• W3213570395 cites W2138274153 @default.
• W3213570395 cites W2138946046 @default.
• W3213570395 cites W2141718280 @default.
• W3213570395 cites W2143944942 @default.
• W3213570395 cites W2144204310 @default.
• W3213570395 cites W2144682968 @default.
• W3213570395 cites W2147455644 @default.
• W3213570395 cites W2149717051 @default.
• W3213570395 cites W2152184106 @default.
• W3213570395 cites W2152281275 @default.
• W3213570395 cites W2156288642 @default.
• W3213570395 cites W2158300991 @default.
• W3213570395 cites W2158427893 @default.
• W3213570395 cites W2159982153 @default.
• W3213570395 cites W2163120110 @default.
• W3213570395 cites W2163991393 @default.
• W3213570395 cites W2166232290 @default.
• W3213570395 cites W2166674462 @default.
• W3213570395 cites W2169029547 @default.
• W3213570395 cites W2169331095 @default.
• W3213570395 cites W2170121306 @default.
• W3213570395 cites W2175625373 @default.
• W3213570395 cites W2272245044 @default.
• W3213570395 cites W2321889575 @default.
• W3213570395 cites W2322006229 @default.
• W3213570395 cites W2323579874 @default.

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