FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213579272> ?p ?o ?g. }

• W3213579272 endingPage "1226" @default.
• W3213579272 startingPage "1226" @default.
• W3213579272 abstract "Background and Objectives: Sarcopenia is commonly associated with liver cirrhosis and predicts clinical outcome. Our aim was to identify the changes in skeletal muscle index (SMI) on computed tomography (CT) examination, as a quantitative marker of sarcopenia, in patients with HCV-related cirrhosis after direct acting antivirals (DAAs) treatment and to assess predictive factors for the evolution of SMI. Materials and Methods: This is a single center retrospective study in patients with HCV-related compensated cirrhosis who obtained sustained virological response (SVR) after DAAs. CT examinations were performed in 52 patients before and within 5-24 months after treatment. The total muscle area (TMA) of abdominal muscle at the level of third lumbar vertebra (L3) was measured at baseline and after SVR. The L3-SMI was calculated from TMA divided by body height squared (cm2/m2). We assessed changes in L3-SMI after SVR according to baseline body mass index (BMI) and laboratory data. Predictive factors were assessed by linear regression model. Results: Patients with L3-SMI above the gender-specific cut-off value at baseline had higher values of serum creatinine (median 0.73) compared to patients with low L3-SMI (median 0.68, p = 0.031). After SVR, 14 patients showed increase of L3-SMI, and 38 patients had a decrease of L3-SMI. BMI in the decreased L3-SMI group was significantly lower (median 26.17) than those without decreased L3-SMI (median 28.84, p = 0.021). ALT values in the decreased L3-SMI group (median 66.5) were significantly lower than those without a decrease in L3-SMI (median 88, p = 0.045). Conclusions: Low creatinine serum level correlates with sarcopenia. SMI was partially influenced by the viral clearance. Lower BMI and ALT serum levels at baseline were predictive for no benefit in terms of muscle mass dynamics. Understanding all the mechanisms involved in sarcopenia and identifying the most vulnerable patients could ensure optimal adapted care strategies." @default.
• W3213579272 created "2021-11-22" @default.
• W3213579272 creator A5002105855 @default.
• W3213579272 creator A5024799287 @default.
• W3213579272 creator A5039504054 @default.
• W3213579272 creator A5053560370 @default.
• W3213579272 creator A5055521342 @default.
• W3213579272 creator A5065124991 @default.
• W3213579272 creator A5066002081 @default.
• W3213579272 creator A5072498353 @default.
• W3213579272 creator A5078932458 @default.
• W3213579272 creator A5082162839 @default.
• W3213579272 creator A5084485316 @default.
• W3213579272 date "2021-11-10" @default.
• W3213579272 modified "2023-09-30" @default.
• W3213579272 title "L3 Skeletal Muscle Index Dynamics in Patients with HCV-Related Compensated Cirrhosis Following Sustained Virological Response after Direct Acting Antiviral Treatment" @default.
• W3213579272 cites W1914337164 @default.
• W3213579272 cites W1991870955 @default.
• W3213579272 cites W2013134494 @default.
• W3213579272 cites W2043161713 @default.
• W3213579272 cites W2107195787 @default.
• W3213579272 cites W2123770204 @default.
• W3213579272 cites W2135646847 @default.
• W3213579272 cites W2147601109 @default.
• W3213579272 cites W2261020375 @default.
• W3213579272 cites W2340307424 @default.
• W3213579272 cites W2341485436 @default.
• W3213579272 cites W2396013415 @default.
• W3213579272 cites W2507464717 @default.
• W3213579272 cites W2611928450 @default.
• W3213579272 cites W2614428059 @default.
• W3213579272 cites W2766252417 @default.
• W3213579272 cites W2888028761 @default.
• W3213579272 cites W2893179068 @default.
• W3213579272 cites W2926325446 @default.
• W3213579272 cites W2967446376 @default.
• W3213579272 cites W2981634288 @default.
• W3213579272 cites W2982005278 @default.
• W3213579272 cites W3012496552 @default.
• W3213579272 cites W3135679180 @default.
• W3213579272 cites W3157405114 @default.
• W3213579272 cites W3171853910 @default.
• W3213579272 cites W3194555987 @default.
• W3213579272 cites W878138526 @default.
• W3213579272 doi "https://doi.org/10.3390/medicina57111226" @default.
• W3213579272 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8623211" @default.
• W3213579272 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34833444" @default.
• W3213579272 hasPublicationYear "2021" @default.
• W3213579272 type Work @default.
• W3213579272 sameAs 3213579272 @default.
• W3213579272 citedByCount "3" @default.
• W3213579272 countsByYear W32135792722023 @default.
• W3213579272 crossrefType "journal-article" @default.
• W3213579272 hasAuthorship W3213579272A5002105855 @default.
• W3213579272 hasAuthorship W3213579272A5024799287 @default.
• W3213579272 hasAuthorship W3213579272A5039504054 @default.
• W3213579272 hasAuthorship W3213579272A5053560370 @default.
• W3213579272 hasAuthorship W3213579272A5055521342 @default.
• W3213579272 hasAuthorship W3213579272A5065124991 @default.
• W3213579272 hasAuthorship W3213579272A5066002081 @default.
• W3213579272 hasAuthorship W3213579272A5072498353 @default.
• W3213579272 hasAuthorship W3213579272A5078932458 @default.
• W3213579272 hasAuthorship W3213579272A5082162839 @default.
• W3213579272 hasAuthorship W3213579272A5084485316 @default.
• W3213579272 hasBestOaLocation W32135792721 @default.
• W3213579272 hasConcept C126322002 @default.
• W3213579272 hasConcept C126894567 @default.
• W3213579272 hasConcept C167135981 @default.
• W3213579272 hasConcept C2776214593 @default.
• W3213579272 hasConcept C2777214474 @default.
• W3213579272 hasConcept C2780073493 @default.
• W3213579272 hasConcept C2780221984 @default.
• W3213579272 hasConcept C2780306776 @default.
• W3213579272 hasConcept C71924100 @default.
• W3213579272 hasConcept C90924648 @default.
• W3213579272 hasConceptScore W3213579272C126322002 @default.
• W3213579272 hasConceptScore W3213579272C126894567 @default.
• W3213579272 hasConceptScore W3213579272C167135981 @default.
• W3213579272 hasConceptScore W3213579272C2776214593 @default.
• W3213579272 hasConceptScore W3213579272C2777214474 @default.
• W3213579272 hasConceptScore W3213579272C2780073493 @default.
• W3213579272 hasConceptScore W3213579272C2780221984 @default.
• W3213579272 hasConceptScore W3213579272C2780306776 @default.
• W3213579272 hasConceptScore W3213579272C71924100 @default.
• W3213579272 hasConceptScore W3213579272C90924648 @default.
• W3213579272 hasIssue "11" @default.
• W3213579272 hasLocation W32135792721 @default.
• W3213579272 hasLocation W32135792722 @default.
• W3213579272 hasLocation W32135792723 @default.
• W3213579272 hasLocation W32135792724 @default.
• W3213579272 hasOpenAccess W3213579272 @default.
• W3213579272 hasPrimaryLocation W32135792721 @default.
• W3213579272 hasRelatedWork W2612021623 @default.
• W3213579272 hasRelatedWork W2899447890 @default.
• W3213579272 hasRelatedWork W2946213312 @default.
• W3213579272 hasRelatedWork W3126505890 @default.
• W3213579272 hasRelatedWork W3130772142 @default.
• W3213579272 hasRelatedWork W3157109166 @default.

• next