FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213757774> ?p ?o ?g. }

• W3213757774 abstract "Abstract Background and aims Chronic kidney disease (CKD) is a global public health problem with an increasing number of patients due to obesity, hypertension, diabetes, and aging. CKD is an independent risk factor for atrial fibrillation (AF) and the incidence of AF in patients with CKD is two- to threefold higher compared to the general population. The relationship between CKD and AF is bidirectional, and the incidence of renal insufficiency is higher in patients with AF. Both AF and CKD are associated with increased risk of stroke and systemic thromboembolism, as well as an increased bleeding risk. The Finnish AntiCoagulation in Atrial Fibrillation (FinACAF) study is a nationwide study among AF patients conducted as a retrospective register-based linkage study combining data from several Finnish health care registers. We aimed to characterize demographics and medications of patients with new-onset AF included FinACAF according to stages of renal function. Method The FinACAF study includes data from 411000 patients covering all Finnish AF patients from 1 January 2004 to 31 December 2018. Using national unique personal identification numbers, individual patients' data from ten nationwide population registries and six regional laboratory databases were linked together. The inclusion criteria of this substudy were all patients 20 years or older with a new-onset AF diagnosis between January 2010 and December 2018 and a measured estimated glomerular filtration rate (eGFR) within the proximity of the AF diagnosis. Drug purchases (date, Anatomical Therapeutic Chemical (ATC) codes, and amount) were obtained from the National Prescription Register upheld by the Social Insurance Institution of Finland. Results 147001 patients from the initial FinACAF cohort were included in this substudy. The mean age at the time of AF diagnosis was 73 years (range 20 to 107 years), 48.9% of the patients were female. The mean age of AF patients increased in various stages of glomerular filtration at the cohort entry during 2010–2018. Baseline medications are shown in Table. The use of nonsteroidal anti-inflammatory drugs (NSAIDs) at the cohort entry decreased from 27.4% to 22.1% during 2010–2018 (p&lt;0.001). Conclusions Medications were used increasingly with worsening renal function, except for NSAIDs. NSAIDs use remained remarkably high in all stages of renal function, albeit much less with the lowest eGFRs. The number of patients with lipid-lowering medication was unexpectedly low considering the high cardiovascular risk in patients with impaired renal function. Funding Acknowledgement Type of funding sources: Foundation. Main funding source(s): This work was supported by Aarne Koskelo Foundation, Yrjö Jahnsson Foundation, The Finnish Foundation for Cardiovascular Research, and Helsinki and Uusimaa Hospital District research fund (TYH2019309)." @default.
• W3213757774 created "2021-11-22" @default.
• W3213757774 creator A5004652809 @default.
• W3213757774 creator A5007412748 @default.
• W3213757774 creator A5012019308 @default.
• W3213757774 creator A5016637101 @default.
• W3213757774 creator A5019383683 @default.
• W3213757774 creator A5034908428 @default.
• W3213757774 creator A5054637221 @default.
• W3213757774 creator A5056075032 @default.
• W3213757774 creator A5056349946 @default.
• W3213757774 creator A5061445522 @default.
• W3213757774 creator A5066458327 @default.
• W3213757774 creator A5069864713 @default.
• W3213757774 creator A5074764762 @default.
• W3213757774 creator A5080377718 @default.
• W3213757774 creator A5085412058 @default.
• W3213757774 date "2021-10-01" @default.
• W3213757774 modified "2023-10-13" @default.
• W3213757774 title "Renal function and use of medication preceding new-onset atrial fibrillation – results from the nationwide FinACAF study" @default.
• W3213757774 doi "https://doi.org/10.1093/eurheartj/ehab724.0590" @default.
• W3213757774 hasPublicationYear "2021" @default.
• W3213757774 type Work @default.
• W3213757774 sameAs 3213757774 @default.
• W3213757774 citedByCount "0" @default.
• W3213757774 crossrefType "journal-article" @default.
• W3213757774 hasAuthorship W3213757774A5004652809 @default.
• W3213757774 hasAuthorship W3213757774A5007412748 @default.
• W3213757774 hasAuthorship W3213757774A5012019308 @default.
• W3213757774 hasAuthorship W3213757774A5016637101 @default.
• W3213757774 hasAuthorship W3213757774A5019383683 @default.
• W3213757774 hasAuthorship W3213757774A5034908428 @default.
• W3213757774 hasAuthorship W3213757774A5054637221 @default.
• W3213757774 hasAuthorship W3213757774A5056075032 @default.
• W3213757774 hasAuthorship W3213757774A5056349946 @default.
• W3213757774 hasAuthorship W3213757774A5061445522 @default.
• W3213757774 hasAuthorship W3213757774A5066458327 @default.
• W3213757774 hasAuthorship W3213757774A5069864713 @default.
• W3213757774 hasAuthorship W3213757774A5074764762 @default.
• W3213757774 hasAuthorship W3213757774A5080377718 @default.
• W3213757774 hasAuthorship W3213757774A5085412058 @default.
• W3213757774 hasBestOaLocation W32137577741 @default.
• W3213757774 hasConcept C120665830 @default.
• W3213757774 hasConcept C121332964 @default.
• W3213757774 hasConcept C126322002 @default.
• W3213757774 hasConcept C127413603 @default.
• W3213757774 hasConcept C134018914 @default.
• W3213757774 hasConcept C159641895 @default.
• W3213757774 hasConcept C164705383 @default.
• W3213757774 hasConcept C167135981 @default.
• W3213757774 hasConcept C177713679 @default.
• W3213757774 hasConcept C187212893 @default.
• W3213757774 hasConcept C194828623 @default.
• W3213757774 hasConcept C2426938 @default.
• W3213757774 hasConcept C2776301958 @default.
• W3213757774 hasConcept C2778653478 @default.
• W3213757774 hasConcept C2779161974 @default.
• W3213757774 hasConcept C2780645631 @default.
• W3213757774 hasConcept C2908647359 @default.
• W3213757774 hasConcept C45827449 @default.
• W3213757774 hasConcept C50440223 @default.
• W3213757774 hasConcept C555293320 @default.
• W3213757774 hasConcept C61511704 @default.
• W3213757774 hasConcept C71924100 @default.
• W3213757774 hasConcept C78519656 @default.
• W3213757774 hasConcept C98274493 @default.
• W3213757774 hasConcept C99454951 @default.
• W3213757774 hasConceptScore W3213757774C120665830 @default.
• W3213757774 hasConceptScore W3213757774C121332964 @default.
• W3213757774 hasConceptScore W3213757774C126322002 @default.
• W3213757774 hasConceptScore W3213757774C127413603 @default.
• W3213757774 hasConceptScore W3213757774C134018914 @default.
• W3213757774 hasConceptScore W3213757774C159641895 @default.
• W3213757774 hasConceptScore W3213757774C164705383 @default.
• W3213757774 hasConceptScore W3213757774C167135981 @default.
• W3213757774 hasConceptScore W3213757774C177713679 @default.
• W3213757774 hasConceptScore W3213757774C187212893 @default.
• W3213757774 hasConceptScore W3213757774C194828623 @default.
• W3213757774 hasConceptScore W3213757774C2426938 @default.
• W3213757774 hasConceptScore W3213757774C2776301958 @default.
• W3213757774 hasConceptScore W3213757774C2778653478 @default.
• W3213757774 hasConceptScore W3213757774C2779161974 @default.
• W3213757774 hasConceptScore W3213757774C2780645631 @default.
• W3213757774 hasConceptScore W3213757774C2908647359 @default.
• W3213757774 hasConceptScore W3213757774C45827449 @default.
• W3213757774 hasConceptScore W3213757774C50440223 @default.
• W3213757774 hasConceptScore W3213757774C555293320 @default.
• W3213757774 hasConceptScore W3213757774C61511704 @default.
• W3213757774 hasConceptScore W3213757774C71924100 @default.
• W3213757774 hasConceptScore W3213757774C78519656 @default.
• W3213757774 hasConceptScore W3213757774C98274493 @default.
• W3213757774 hasConceptScore W3213757774C99454951 @default.
• W3213757774 hasIssue "Supplement_1" @default.
• W3213757774 hasLocation W32137577741 @default.
• W3213757774 hasOpenAccess W3213757774 @default.
• W3213757774 hasPrimaryLocation W32137577741 @default.
• W3213757774 hasRelatedWork W1983415041 @default.
• W3213757774 hasRelatedWork W2003235938 @default.
• W3213757774 hasRelatedWork W2081145557 @default.
• W3213757774 hasRelatedWork W2114223015 @default.

• next