FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213927780> ?p ?o ?g. }

• W3213927780 endingPage "101593" @default.
• W3213927780 startingPage "101593" @default.
• W3213927780 abstract "Fine particulate matter (PM2.5) from poultry houses has adverse effects on the health of animals and workers. Tert-butylhydroquinone (TBHQ), an antioxidant, is widely used in feed additives. The present study investigated the effects of TBHQ on broiler house PM2.5-induced damage in chicken primary alveolar epithelial cells (AECII) extracted from 16-day-old chicken embryos using the method of differential adhesion. AECII were exposed to PM2.5 and TBHQ alone or in combination, and then, cell membrane integrity, pyroptosis, and necroptosis were detected. Our results showed that PM2.5 from broiler houses caused cell rupture and loss of cell membrane integrity. This result was confirmed by the obvious increases in lactate dehydrogenase (LDH) release and propidium iodide (PI)-positive cells compared to the control group. In addition, the intracellular reactive oxygen species (ROS) levels and the expression levels of pyroptosis-related genes (NLRP3, IL-18, IL-1β) and necroptosis-related genes (RIPK3) were also significantly enhanced. However, TBHQ significantly inhibited intracellular ROS, improved cell viability, and reduced the release of LDH and the number of PI-positive cells compared to those in the PM2.5 group. The expression levels of pyroptosis-related genes (Caspase-1, NLRP3, IL-18, IL-1β) and necroptosis-related genes (RIPK3) were also significantly decreased in the co-treatment group. In summary, these results indicated that TBHQ can alleviate PM2.5-mediated cell pyroptosis and necroptosis in chicken AECII and provide a basis for overcoming the danger that air pollutants from broiler houses pose to the health of chickens." @default.
• W3213927780 created "2021-11-22" @default.
• W3213927780 creator A5010841246 @default.
• W3213927780 creator A5031550515 @default.
• W3213927780 creator A5063759402 @default.
• W3213927780 creator A5067453012 @default.
• W3213927780 creator A5070757563 @default.
• W3213927780 date "2022-02-01" @default.
• W3213927780 modified "2023-10-09" @default.
• W3213927780 title "TBHQ alleviates pyroptosis and necroptosis in chicken alveolar epithelial cells induced by fine particulate matter from broiler houses" @default.
• W3213927780 cites W1514094219 @default.
• W3213927780 cites W1523845694 @default.
• W3213927780 cites W1529674879 @default.
• W3213927780 cites W1785455093 @default.
• W3213927780 cites W1891826181 @default.
• W3213927780 cites W1972041291 @default.
• W3213927780 cites W1975667190 @default.
• W3213927780 cites W1981790437 @default.
• W3213927780 cites W2012672361 @default.
• W3213927780 cites W2016469998 @default.
• W3213927780 cites W2031456306 @default.
• W3213927780 cites W2038815580 @default.
• W3213927780 cites W2042558274 @default.
• W3213927780 cites W2044437167 @default.
• W3213927780 cites W2053108974 @default.
• W3213927780 cites W2078162308 @default.
• W3213927780 cites W2078896740 @default.
• W3213927780 cites W2091900102 @default.
• W3213927780 cites W2093582996 @default.
• W3213927780 cites W2103760631 @default.
• W3213927780 cites W2118395008 @default.
• W3213927780 cites W2120137661 @default.
• W3213927780 cites W2149853493 @default.
• W3213927780 cites W2160688028 @default.
• W3213927780 cites W2207241376 @default.
• W3213927780 cites W2319054200 @default.
• W3213927780 cites W2415223431 @default.
• W3213927780 cites W2417544724 @default.
• W3213927780 cites W2418456889 @default.
• W3213927780 cites W2590567160 @default.
• W3213927780 cites W2783543761 @default.
• W3213927780 cites W2789997601 @default.
• W3213927780 cites W2797873249 @default.
• W3213927780 cites W2810056263 @default.
• W3213927780 cites W2890663000 @default.
• W3213927780 cites W2922376273 @default.
• W3213927780 cites W2960695456 @default.
• W3213927780 cites W2972940744 @default.
• W3213927780 cites W2981236933 @default.
• W3213927780 cites W2990363633 @default.
• W3213927780 cites W3087297820 @default.
• W3213927780 doi "https://doi.org/10.1016/j.psj.2021.101593" @default.
• W3213927780 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34963088" @default.
• W3213927780 hasPublicationYear "2022" @default.
• W3213927780 type Work @default.
• W3213927780 sameAs 3213927780 @default.
• W3213927780 citedByCount "5" @default.
• W3213927780 countsByYear W32139277802022 @default.
• W3213927780 countsByYear W32139277802023 @default.
• W3213927780 crossrefType "journal-article" @default.
• W3213927780 hasAuthorship W3213927780A5010841246 @default.
• W3213927780 hasAuthorship W3213927780A5031550515 @default.
• W3213927780 hasAuthorship W3213927780A5063759402 @default.
• W3213927780 hasAuthorship W3213927780A5067453012 @default.
• W3213927780 hasAuthorship W3213927780A5070757563 @default.
• W3213927780 hasBestOaLocation W32139277801 @default.
• W3213927780 hasConcept C1491633281 @default.
• W3213927780 hasConcept C17172800 @default.
• W3213927780 hasConcept C181199279 @default.
• W3213927780 hasConcept C185592680 @default.
• W3213927780 hasConcept C190283241 @default.
• W3213927780 hasConcept C2777318727 @default.
• W3213927780 hasConcept C2780289900 @default.
• W3213927780 hasConcept C31573885 @default.
• W3213927780 hasConcept C31903555 @default.
• W3213927780 hasConcept C53227056 @default.
• W3213927780 hasConcept C55493867 @default.
• W3213927780 hasConcept C79879829 @default.
• W3213927780 hasConcept C94030615 @default.
• W3213927780 hasConceptScore W3213927780C1491633281 @default.
• W3213927780 hasConceptScore W3213927780C17172800 @default.
• W3213927780 hasConceptScore W3213927780C181199279 @default.
• W3213927780 hasConceptScore W3213927780C185592680 @default.
• W3213927780 hasConceptScore W3213927780C190283241 @default.
• W3213927780 hasConceptScore W3213927780C2777318727 @default.
• W3213927780 hasConceptScore W3213927780C2780289900 @default.
• W3213927780 hasConceptScore W3213927780C31573885 @default.
• W3213927780 hasConceptScore W3213927780C31903555 @default.
• W3213927780 hasConceptScore W3213927780C53227056 @default.
• W3213927780 hasConceptScore W3213927780C55493867 @default.
• W3213927780 hasConceptScore W3213927780C79879829 @default.
• W3213927780 hasConceptScore W3213927780C94030615 @default.
• W3213927780 hasFunder F4320321001 @default.
• W3213927780 hasIssue "2" @default.
• W3213927780 hasLocation W32139277801 @default.
• W3213927780 hasLocation W32139277802 @default.
• W3213927780 hasLocation W32139277803 @default.
• W3213927780 hasLocation W32139277804 @default.

• next