FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3213976693> ?p ?o ?g. }

• W3213976693 endingPage "13" @default.
• W3213976693 startingPage "1" @default.
• W3213976693 abstract "To systematically review the evidence about the effect of neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) with pure urothelial carcinoma (pUC) in radical cystectomy (RC) candidates affected by variant histology (VH) bladder cancer.A review of the current literature was conducted through the Medline and National Center for Biotechnology Information (NCBI) PubMed, Scopus databases in May 2020. The updated Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed for this systematic review. Keywords used were 'bladder cancer', 'bladder carcinoma', 'bladder tumour' and 'bladder cancer variants' and 'neoadjuvant chemotherapy'. Only original articles in English published after 2000 and reporting oncological outcomes a series of more than five patients with VH were included. We excluded series in which the oncological outcomes of patients with pUC and VH were undistinguishable.The literature search identified 2231 articles. A total of 51 full-text articles were assessed for eligibility, with 17 eventually considered for systematic review, for a cohort of 450,367 patients, of which 5010 underwent NAC + RC. The median age at initial diagnosis ranged from 61 to 71 years. Most patients received cisplatin-gemcitabine, methotrexate-vinblastine-adriamycin-cisplatin, or carboplatin-based chemotherapy. Only one study reported results of neoadjuvant immunotherapy. The median follow-up ranged from 1 to 120 months. The results showed that squamous cell carcinoma (SCC) is less sensitive to NAC than pUC and that SCC predicts poorer prognosis. NAC was found to be a valid approach in treating small cell carcinoma and may have potential benefit in micropapillary carcinoma.NAC showed the best oncological outcomes in small cell variants and micropapillary carcinoma, while NAC survival benefit for SCC and adenocarcinoma variants needs further studies. Drawing definite considerations on the efficacy of NAC in VH is complicated due to the heterogeneity of present literature. Present results need to be confirmed in randomised controlled trials." @default.
• W3213976693 created "2021-11-22" @default.
• W3213976693 creator A5018034940 @default.
• W3213976693 creator A5024761996 @default.
• W3213976693 creator A5040296751 @default.
• W3213976693 creator A5042883435 @default.
• W3213976693 creator A5049431084 @default.
• W3213976693 creator A5054516578 @default.
• W3213976693 creator A5062997136 @default.
• W3213976693 creator A5080474278 @default.
• W3213976693 creator A5088714640 @default.
• W3213976693 date "2021-11-07" @default.
• W3213976693 modified "2023-10-18" @default.
• W3213976693 title "The effect of neoadjuvant chemotherapy among patients undergoing radical cystectomy for variant histology bladder cancer: A systematic review" @default.
• W3213976693 cites W1558385747 @default.
• W3213976693 cites W1576738591 @default.
• W3213976693 cites W1581476904 @default.
• W3213976693 cites W1598602811 @default.
• W3213976693 cites W1828448189 @default.
• W3213976693 cites W1975918912 @default.
• W3213976693 cites W1984543160 @default.
• W3213976693 cites W2029132015 @default.
• W3213976693 cites W2033775272 @default.
• W3213976693 cites W2037929227 @default.
• W3213976693 cites W2045395111 @default.
• W3213976693 cites W2083397917 @default.
• W3213976693 cites W2097845786 @default.
• W3213976693 cites W2103561213 @default.
• W3213976693 cites W2156098321 @default.
• W3213976693 cites W2160320035 @default.
• W3213976693 cites W2163823502 @default.
• W3213976693 cites W2164791945 @default.
• W3213976693 cites W2166453367 @default.
• W3213976693 cites W2168846224 @default.
• W3213976693 cites W2286136178 @default.
• W3213976693 cites W2332342311 @default.
• W3213976693 cites W246286872 @default.
• W3213976693 cites W2473580126 @default.
• W3213976693 cites W2531269403 @default.
• W3213976693 cites W2533972019 @default.
• W3213976693 cites W2561202547 @default.
• W3213976693 cites W2561739294 @default.
• W3213976693 cites W2569407814 @default.
• W3213976693 cites W2737911811 @default.
• W3213976693 cites W2738951134 @default.
• W3213976693 cites W2804894884 @default.
• W3213976693 cites W2810579527 @default.
• W3213976693 cites W2903155409 @default.
• W3213976693 cites W2904555583 @default.
• W3213976693 cites W2910754226 @default.
• W3213976693 cites W2911525595 @default.
• W3213976693 cites W2912264066 @default.
• W3213976693 cites W2912973297 @default.
• W3213976693 cites W2988581606 @default.
• W3213976693 cites W3004971171 @default.
• W3213976693 cites W3023288864 @default.
• W3213976693 cites W3035230667 @default.
• W3213976693 cites W3043096196 @default.
• W3213976693 cites W4294215472 @default.
• W3213976693 cites W4377854801 @default.
• W3213976693 doi "https://doi.org/10.1080/2090598x.2021.1994230" @default.
• W3213976693 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35223104" @default.
• W3213976693 hasPublicationYear "2021" @default.
• W3213976693 type Work @default.
• W3213976693 sameAs 3213976693 @default.
• W3213976693 citedByCount "6" @default.
• W3213976693 countsByYear W32139766932022 @default.
• W3213976693 countsByYear W32139766932023 @default.
• W3213976693 crossrefType "journal-article" @default.
• W3213976693 hasAuthorship W3213976693A5018034940 @default.
• W3213976693 hasAuthorship W3213976693A5024761996 @default.
• W3213976693 hasAuthorship W3213976693A5040296751 @default.
• W3213976693 hasAuthorship W3213976693A5042883435 @default.
• W3213976693 hasAuthorship W3213976693A5049431084 @default.
• W3213976693 hasAuthorship W3213976693A5054516578 @default.
• W3213976693 hasAuthorship W3213976693A5062997136 @default.
• W3213976693 hasAuthorship W3213976693A5080474278 @default.
• W3213976693 hasAuthorship W3213976693A5088714640 @default.
• W3213976693 hasBestOaLocation W32139766931 @default.
• W3213976693 hasConcept C121608353 @default.
• W3213976693 hasConcept C126322002 @default.
• W3213976693 hasConcept C143998085 @default.
• W3213976693 hasConcept C2775910329 @default.
• W3213976693 hasConcept C2776694085 @default.
• W3213976693 hasConcept C2777132456 @default.
• W3213976693 hasConcept C2777546739 @default.
• W3213976693 hasConcept C2778239845 @default.
• W3213976693 hasConcept C2780258809 @default.
• W3213976693 hasConcept C2780352672 @default.
• W3213976693 hasConcept C2781451048 @default.
• W3213976693 hasConcept C71924100 @default.
• W3213976693 hasConceptScore W3213976693C121608353 @default.
• W3213976693 hasConceptScore W3213976693C126322002 @default.
• W3213976693 hasConceptScore W3213976693C143998085 @default.
• W3213976693 hasConceptScore W3213976693C2775910329 @default.
• W3213976693 hasConceptScore W3213976693C2776694085 @default.
• W3213976693 hasConceptScore W3213976693C2777132456 @default.
• W3213976693 hasConceptScore W3213976693C2777546739 @default.

• next