Matches in SemOpenAlex for { <https://semopenalex.org/work/W3214072256> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3214072256 endingPage "24" @default.
- W3214072256 startingPage "16" @default.
- W3214072256 abstract "Label-free measurements using impedance sensing could enable microfluidic chip electrophoresis (ME) to be used in point-of-care (POC) diagnostics. However, impedance sensing methods reported in this field need considerable optimisation. GOAL: Develop a novel design process for optimising tetrapolar electrical impedance measurement (TEIM) sensor performance in ME applications through a systematic investigation a) of the impact of a TEIM sensor’s design parameters on its performance in ME and b) of the relationship between the above parameters with those of the microfluidic channel and the sample to be sensed. METHODS: 3D FEM sensitivity simulations, verified experimentally, were carried out to study the impact of sensor and channel parameters on the measured impedance and their interrelationship. Subsequently, the impact of sensor parameters on sensing a sample band’s conductivity and size was investigated. RESULTS: The impact of channel dimensions on transfer impedance measurements is significant. The non-linearity reported for transfer impedance measurement of volume conductors can be manipulated by appropriate sensor parameter design. The sensor performance can be optimised by designing electrode length and measurement electrode distance in relation to the channel height and sample band length, respectively. The sensor performance is not affected by the injection electrode distance. CONCLUSION: There is a relationship between sensor, channel and band parameters and this warrants establishing a systematic design process of TEIM sensors in ME. SIGNIFICANCE: This paper presents a novel approach to optimising the design of TEIM sensors in ME potentially providing significant performance improvements and thus allowing for label-free POC electrophoresis diagnostics." @default.
- W3214072256 created "2021-11-22" @default.
- W3214072256 creator A5032300904 @default.
- W3214072256 creator A5057258184 @default.
- W3214072256 date "2022-01-01" @default.
- W3214072256 modified "2023-09-25" @default.
- W3214072256 title "Optimisation of an Electrical Impedance Sensor for Use in Microfluidic Chip Electrophoresis" @default.
- W3214072256 cites W1946581574 @default.
- W3214072256 cites W1966154027 @default.
- W3214072256 cites W1970522261 @default.
- W3214072256 cites W1979724394 @default.
- W3214072256 cites W1982830963 @default.
- W3214072256 cites W2027118734 @default.
- W3214072256 cites W2029352896 @default.
- W3214072256 cites W2036207072 @default.
- W3214072256 cites W2038386319 @default.
- W3214072256 cites W2052955597 @default.
- W3214072256 cites W2054483093 @default.
- W3214072256 cites W2057591581 @default.
- W3214072256 cites W2064330536 @default.
- W3214072256 cites W2066323414 @default.
- W3214072256 cites W2070461025 @default.
- W3214072256 cites W2091551132 @default.
- W3214072256 cites W2092132796 @default.
- W3214072256 cites W2116881503 @default.
- W3214072256 cites W2146007440 @default.
- W3214072256 cites W2153697803 @default.
- W3214072256 cites W2617877002 @default.
- W3214072256 cites W2749683872 @default.
- W3214072256 cites W2887155146 @default.
- W3214072256 cites W2898762551 @default.
- W3214072256 cites W2910366781 @default.
- W3214072256 cites W3080314515 @default.
- W3214072256 doi "https://doi.org/10.1109/jsen.2021.3127320" @default.
- W3214072256 hasPublicationYear "2022" @default.
- W3214072256 type Work @default.
- W3214072256 sameAs 3214072256 @default.
- W3214072256 citedByCount "1" @default.
- W3214072256 countsByYear W32140722562023 @default.
- W3214072256 crossrefType "journal-article" @default.
- W3214072256 hasAuthorship W3214072256A5032300904 @default.
- W3214072256 hasAuthorship W3214072256A5057258184 @default.
- W3214072256 hasConcept C119599485 @default.
- W3214072256 hasConcept C127162648 @default.
- W3214072256 hasConcept C127413603 @default.
- W3214072256 hasConcept C165005293 @default.
- W3214072256 hasConcept C171250308 @default.
- W3214072256 hasConcept C17829176 @default.
- W3214072256 hasConcept C192562407 @default.
- W3214072256 hasConcept C21200559 @default.
- W3214072256 hasConcept C24326235 @default.
- W3214072256 hasConcept C77170095 @default.
- W3214072256 hasConcept C8673954 @default.
- W3214072256 hasConceptScore W3214072256C119599485 @default.
- W3214072256 hasConceptScore W3214072256C127162648 @default.
- W3214072256 hasConceptScore W3214072256C127413603 @default.
- W3214072256 hasConceptScore W3214072256C165005293 @default.
- W3214072256 hasConceptScore W3214072256C171250308 @default.
- W3214072256 hasConceptScore W3214072256C17829176 @default.
- W3214072256 hasConceptScore W3214072256C192562407 @default.
- W3214072256 hasConceptScore W3214072256C21200559 @default.
- W3214072256 hasConceptScore W3214072256C24326235 @default.
- W3214072256 hasConceptScore W3214072256C77170095 @default.
- W3214072256 hasConceptScore W3214072256C8673954 @default.
- W3214072256 hasIssue "1" @default.
- W3214072256 hasLocation W32140722561 @default.
- W3214072256 hasOpenAccess W3214072256 @default.
- W3214072256 hasPrimaryLocation W32140722561 @default.
- W3214072256 hasRelatedWork W1977501065 @default.
- W3214072256 hasRelatedWork W2035445439 @default.
- W3214072256 hasRelatedWork W2090769959 @default.
- W3214072256 hasRelatedWork W2159855468 @default.
- W3214072256 hasRelatedWork W2296761060 @default.
- W3214072256 hasRelatedWork W2594343900 @default.
- W3214072256 hasRelatedWork W2727522171 @default.
- W3214072256 hasRelatedWork W2897894601 @default.
- W3214072256 hasRelatedWork W4200025276 @default.
- W3214072256 hasRelatedWork W4312719148 @default.
- W3214072256 hasVolume "22" @default.
- W3214072256 isParatext "false" @default.
- W3214072256 isRetracted "false" @default.
- W3214072256 magId "3214072256" @default.
- W3214072256 workType "article" @default.