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• W3214156939 abstract "We designed an efficient self-quenching fluorescence probe and constructed this probe-mediated exponential isothermal amplification system for miRNA detection. Owing to the significant improvement in the detective signal-to-background ratio, a wide dynamic range of 9 orders of magnitude and a limit of detection as low as 0.08 aM can be easily achieved in a single step. Furthermore, benefiting from the additional advantages of high specificity and biocompatibility, the proposed method has been demonstrated to be capable of accurately quantifying miRNA biomarkers in serum, which will provide promising perspectives for clinical diagnosis." @default.
• W3214156939 created "2021-11-22" @default.
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• W3214156939 date "2021-01-01" @default.
• W3214156939 modified "2023-09-30" @default.
• W3214156939 title "A self-quenching fluorescence probe-mediated exponential isothermal amplification system for highly sensitive and specific detection of microRNAs" @default.
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• W3214156939 doi "https://doi.org/10.1039/d1cc05522d" @default.
• W3214156939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34786586" @default.
• W3214156939 hasPublicationYear "2021" @default.
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