FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3214545017> ?p ?o ?g. }

• W3214545017 abstract "OBJECTIVE: Thrombocytopenia is a common manifestation of cirrhosis. The aim of this study was to examine the relationship between serum thrombopoietin concentrations, circulating platelet levels, and the stage of hepatic fibrosis in patients with chronic viral hepatitis.METHODS: The study included 48 patients with chronic viral hepatitis (14 with stage 1 fibrosis; five with stage 2 fibrosis; three with stage 3 fibrosis; 26 with cirrhosis) and 30 healthy volunteers. Serum thrombopoietin levels were measured using an enzyme-linked immunosorbent assay. Spleen size, platelet counts, and prothrombin time were measured.RESULTS: Thrombopoietin levels of patients with fibrosis stage 1 (2.50 ± 1.60 fmol/ml) or stage 2 (1.89 ± 0.65) were significantly higher than those in patients with cirrhosis (1.21 ± 0.55) or healthy volunteers (1.26 ± 0.74). Mean platelet counts of patients with cirrhosis (8.0 ± 4.6 × 104/μl) were significantly lower than those with fibrosis stage 1 (18.6 ± 3.9) or stage 2 (16.0 ± 5.8), or healthy volunteers (24.5 ± 7.3). Patients with cirrhosis had larger spleens (30.9 ± 18.4 cm2) than those with fibrosis stage 1 (18.2 ± 6.4). Platelet counts showed a significant inverse relationship to spleen size (ρ = −0.51, p < 0.0005) and a significant positive relationship with thrombopoietin levels (ρ = 0.34, p < 0.02). Thrombopoietin levels were significantly correlated to prothrombin time (ρ = 0.45, p < 0.005).CONCLUSIONS: Serum thrombopoietin levels are elevated in patients with an early stage of chronic viral hepatitis. As the disease progresses from mild fibrosis to cirrhosis, decreased production of thrombopoietin may contribute to the further development of thrombocytopenia in cirrhosis." @default.
• W3214545017 created "2021-11-22" @default.
• W3214545017 creator A5003439613 @default.
• W3214545017 creator A5018016302 @default.
• W3214545017 creator A5025770439 @default.
• W3214545017 creator A5030273674 @default.
• W3214545017 creator A5035113984 @default.
• W3214545017 creator A5042331400 @default.
• W3214545017 creator A5044838871 @default.
• W3214545017 creator A5047669789 @default.
• W3214545017 creator A5055271043 @default.
• W3214545017 creator A5058303073 @default.
• W3214545017 creator A5063488239 @default.
• W3214545017 creator A5065901351 @default.
• W3214545017 creator A5082230048 @default.
• W3214545017 creator A5084522512 @default.
• W3214545017 date "1999-07-01" @default.
• W3214545017 modified "2023-10-15" @default.
• W3214545017 title "Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis" @default.
• W3214545017 doi "https://doi.org/10.1016/s0002-9270(99)00287-7" @default.
• W3214545017 hasPublicationYear "1999" @default.
• W3214545017 type Work @default.
• W3214545017 sameAs 3214545017 @default.
• W3214545017 citedByCount "5" @default.
• W3214545017 countsByYear W32145450172019 @default.
• W3214545017 crossrefType "journal-article" @default.
• W3214545017 hasAuthorship W3214545017A5003439613 @default.
• W3214545017 hasAuthorship W3214545017A5018016302 @default.
• W3214545017 hasAuthorship W3214545017A5025770439 @default.
• W3214545017 hasAuthorship W3214545017A5030273674 @default.
• W3214545017 hasAuthorship W3214545017A5035113984 @default.
• W3214545017 hasAuthorship W3214545017A5042331400 @default.
• W3214545017 hasAuthorship W3214545017A5044838871 @default.
• W3214545017 hasAuthorship W3214545017A5047669789 @default.
• W3214545017 hasAuthorship W3214545017A5055271043 @default.
• W3214545017 hasAuthorship W3214545017A5058303073 @default.
• W3214545017 hasAuthorship W3214545017A5063488239 @default.
• W3214545017 hasAuthorship W3214545017A5065901351 @default.
• W3214545017 hasAuthorship W3214545017A5082230048 @default.
• W3214545017 hasAuthorship W3214545017A5084522512 @default.
• W3214545017 hasConcept C109159458 @default.
• W3214545017 hasConcept C126322002 @default.
• W3214545017 hasConcept C146357865 @default.
• W3214545017 hasConcept C151730666 @default.
• W3214545017 hasConcept C2777072776 @default.
• W3214545017 hasConcept C2777075537 @default.
• W3214545017 hasConcept C2777214474 @default.
• W3214545017 hasConcept C2777863708 @default.
• W3214545017 hasConcept C2780434524 @default.
• W3214545017 hasConcept C2780559512 @default.
• W3214545017 hasConcept C2780931953 @default.
• W3214545017 hasConcept C28328180 @default.
• W3214545017 hasConcept C54355233 @default.
• W3214545017 hasConcept C71924100 @default.
• W3214545017 hasConcept C86803240 @default.
• W3214545017 hasConcept C89560881 @default.
• W3214545017 hasConcept C90924648 @default.
• W3214545017 hasConceptScore W3214545017C109159458 @default.
• W3214545017 hasConceptScore W3214545017C126322002 @default.
• W3214545017 hasConceptScore W3214545017C146357865 @default.
• W3214545017 hasConceptScore W3214545017C151730666 @default.
• W3214545017 hasConceptScore W3214545017C2777072776 @default.
• W3214545017 hasConceptScore W3214545017C2777075537 @default.
• W3214545017 hasConceptScore W3214545017C2777214474 @default.
• W3214545017 hasConceptScore W3214545017C2777863708 @default.
• W3214545017 hasConceptScore W3214545017C2780434524 @default.
• W3214545017 hasConceptScore W3214545017C2780559512 @default.
• W3214545017 hasConceptScore W3214545017C2780931953 @default.
• W3214545017 hasConceptScore W3214545017C28328180 @default.
• W3214545017 hasConceptScore W3214545017C54355233 @default.
• W3214545017 hasConceptScore W3214545017C71924100 @default.
• W3214545017 hasConceptScore W3214545017C86803240 @default.
• W3214545017 hasConceptScore W3214545017C89560881 @default.
• W3214545017 hasConceptScore W3214545017C90924648 @default.
• W3214545017 hasLocation W32145450171 @default.
• W3214545017 hasOpenAccess W3214545017 @default.
• W3214545017 hasPrimaryLocation W32145450171 @default.
• W3214545017 hasRelatedWork W139735588 @default.
• W3214545017 hasRelatedWork W1516563659 @default.
• W3214545017 hasRelatedWork W1587937581 @default.
• W3214545017 hasRelatedWork W2093476267 @default.
• W3214545017 hasRelatedWork W2154379810 @default.
• W3214545017 hasRelatedWork W2333213874 @default.
• W3214545017 hasRelatedWork W2353005066 @default.
• W3214545017 hasRelatedWork W2353009008 @default.
• W3214545017 hasRelatedWork W2360189088 @default.
• W3214545017 hasRelatedWork W2370167788 @default.
• W3214545017 hasRelatedWork W2375460246 @default.
• W3214545017 hasRelatedWork W2377818387 @default.
• W3214545017 hasRelatedWork W2379566638 @default.
• W3214545017 hasRelatedWork W2380346096 @default.
• W3214545017 hasRelatedWork W2408920451 @default.
• W3214545017 hasRelatedWork W2411957024 @default.
• W3214545017 hasRelatedWork W2503956684 @default.
• W3214545017 hasRelatedWork W2791880342 @default.
• W3214545017 hasRelatedWork W2940418684 @default.
• W3214545017 hasRelatedWork W2988069598 @default.
• W3214545017 isParatext "false" @default.
• W3214545017 isRetracted "false" @default.
• W3214545017 magId "3214545017" @default.

• next