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- W3214581036 endingPage "1658" @default.
- W3214581036 startingPage "1658" @default.
- W3214581036 abstract "Animal digestive systems host microorganism ecosystems, including integrated bacteria, viruses, fungi, and others, that produce a variety of compounds from different substrates with healthy properties. Among these substrates, α-galacto-oligosaccharides (GOS) are considered prebiotics that promote the grow of gut microbiota with a metabolic output of Short Chain Fatty Acids (SCFAs). In this regard, we evaluated Lupinus albus GOS (LA-GOS) as a natural prebiotic using different animal models. Therefore, the aim of this work was to evaluate the effect of LA-GOS on the gut microbiota, SCFA production, and intestinal health in healthy and induced dysbiosis conditions (an ulcerative colitis (UC) model). Twenty C57BL/6 mice were randomly allocated in four groups (n = 5/group): untreated and treated non-induced animals, and two groups induced with 2% dextran sulfate sodium to UC with and without LA-GOS administration (2.5 g/kg bw). We found that the UC treated group showed a higher goblet cell number, lower disease activity index, and reduced histopathological damage in comparison to the UC untreated group. In addition, the abundance of positive bacteria to butyryl-CoA transferase in gut microbiota was significantly increased by LA-GOS treatment, in healthy conditions. We measured the SCFA production with significant differences in the butyrate concentration between treated and untreated healthy groups. Finally, the pH level in cecum feces was reduced after LA-GOS treatment. Overall, we point out the in vivo health benefits of LA-GOS administration on the preservation of the intestinal ecosystem and the promotion of SCFA production." @default.
- W3214581036 created "2021-11-22" @default.
- W3214581036 creator A5005268045 @default.
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- W3214581036 creator A5060197758 @default.
- W3214581036 creator A5061617161 @default.
- W3214581036 creator A5081895979 @default.
- W3214581036 date "2021-11-09" @default.
- W3214581036 modified "2023-10-17" @default.
- W3214581036 title "In Vivo Healthy Benefits of Galacto-Oligosaccharides from Lupinus albus (LA-GOS) in Butyrate Production through Intestinal Microbiota" @default.
- W3214581036 cites W13022575 @default.
- W3214581036 cites W1596258860 @default.
- W3214581036 cites W1756520452 @default.
- W3214581036 cites W1932345506 @default.
- W3214581036 cites W1976808378 @default.
- W3214581036 cites W1988706813 @default.
- W3214581036 cites W1996933969 @default.
- W3214581036 cites W2000422049 @default.
- W3214581036 cites W2000517476 @default.
- W3214581036 cites W2007489219 @default.
- W3214581036 cites W2008505563 @default.
- W3214581036 cites W2020766218 @default.
- W3214581036 cites W2026240985 @default.
- W3214581036 cites W2029180586 @default.
- W3214581036 cites W2032230795 @default.
- W3214581036 cites W2037917079 @default.
- W3214581036 cites W2047216155 @default.
- W3214581036 cites W2052179475 @default.
- W3214581036 cites W2054186211 @default.
- W3214581036 cites W2060789691 @default.
- W3214581036 cites W2066209040 @default.
- W3214581036 cites W2080372464 @default.
- W3214581036 cites W2087435956 @default.
- W3214581036 cites W2090037571 @default.
- W3214581036 cites W2107277218 @default.
- W3214581036 cites W2110936821 @default.
- W3214581036 cites W2117595393 @default.
- W3214581036 cites W2120665071 @default.
- W3214581036 cites W2122292170 @default.
- W3214581036 cites W2122935354 @default.
- W3214581036 cites W2123770816 @default.
- W3214581036 cites W2128933212 @default.
- W3214581036 cites W2128992702 @default.
- W3214581036 cites W2129412558 @default.
- W3214581036 cites W2130902958 @default.
- W3214581036 cites W2133275312 @default.
- W3214581036 cites W2147790901 @default.
- W3214581036 cites W2158117887 @default.
- W3214581036 cites W2158198131 @default.
- W3214581036 cites W2160427027 @default.
- W3214581036 cites W2165971615 @default.
- W3214581036 cites W2166569595 @default.
- W3214581036 cites W2167084464 @default.
- W3214581036 cites W2236332835 @default.
- W3214581036 cites W2274927794 @default.
- W3214581036 cites W2282358425 @default.
- W3214581036 cites W2317733264 @default.
- W3214581036 cites W2337372962 @default.
- W3214581036 cites W2344885638 @default.
- W3214581036 cites W2470512478 @default.
- W3214581036 cites W2505068110 @default.
- W3214581036 cites W2507575989 @default.
- W3214581036 cites W2550084345 @default.
- W3214581036 cites W2559864085 @default.
- W3214581036 cites W2605052214 @default.
- W3214581036 cites W2627092521 @default.
- W3214581036 cites W2736345078 @default.
- W3214581036 cites W2744735757 @default.
- W3214581036 cites W2747022400 @default.
- W3214581036 cites W2763122985 @default.
- W3214581036 cites W2778416039 @default.
- W3214581036 cites W2782401411 @default.
- W3214581036 cites W2791904618 @default.
- W3214581036 cites W2794833162 @default.
- W3214581036 cites W2800205810 @default.
- W3214581036 cites W2808419754 @default.
- W3214581036 cites W2855536711 @default.
- W3214581036 cites W2899648148 @default.
- W3214581036 cites W2905115218 @default.
- W3214581036 cites W2919081348 @default.
- W3214581036 cites W2921966151 @default.
- W3214581036 cites W2929560527 @default.
- W3214581036 cites W2947889850 @default.
- W3214581036 cites W2951095666 @default.
- W3214581036 cites W2952564192 @default.
- W3214581036 cites W2952713182 @default.
- W3214581036 cites W2954879634 @default.
- W3214581036 cites W2955648171 @default.
- W3214581036 cites W2972558607 @default.
- W3214581036 cites W2974724150 @default.
- W3214581036 cites W2978085879 @default.
- W3214581036 cites W2978282877 @default.
- W3214581036 cites W2982628809 @default.
- W3214581036 cites W2989646405 @default.